Survey of trainee attitudes to skill development and simulation training in trauma and orthopaedics.

Background: Simulation training in surgery is widespread and allows surgeons to practise novel operative techniques and acquaint themselves with unfamiliar surgical procedures. The use of box or virtual reality simulators in many surgical specialities is established; however, its use within trauma and orthopaedics (T&O) in the UK and the attitudes of trainee towards it are not known. The aim of this study is to explore the experiences and opinions of T&O trainees towards simulation training. Methods: An electronic survey consisting of 11 questions on the experiences of simulation training and attitudes towards it was sent to all T&O speciality trainees in London. Results: Fewer than 10% of the responders had used or had ready access to simulators to prepare for unfamiliar operations, with almost 90% preferring to read about them in a journal or watch them on an online video site. Over half had only seen simulators on courses or been aware of them. Over 75% of the responders believed that simulators should be available for trainees, but most did not feel that they should be used as part of formal assessments. Conclusions: Methods for preparing for new operations have expanded over the past 20 years, yet the use of simulator machines is not widespread. Many trainees believe current machines are not widely available nor realistic enough to be useful, with most preferring online videos and operative technique books for preparing for an unfamiliar operation.

Reliable and highly sensitive biosensor from suspended MoS2 atomic layer on nano-gap electrodes.

The uneven morphology and the trapped charges at the surface of the traditionally used supporting substrate-based 2D biosensors produces a scattering effect, which leads to a irregular signals from individually fabricated devices. Though suspended 2D channel material has the potential to overcome scattering effects from the substrates but achieving reliability and selectivity, have been limiting the using of this biosensor technology. Here, we have demonstrated nanogap electrodes fabrication by using the self-assembly technique, which provides suspension to the 2D-MoS2. These nano-spacing electrodes not only give suspension but also provide robustness strength to the atomic layer, which remains freestanding after coating of the Hafnium oxide (HfO2) as well as linkers and antibodies. For evaluating the electrical characteristics of suspended MoS2 FET, gating potential was applied through an electrolyte on the suspended MoS2 transistor. This helped in achieved a lower subthreshold swing 70 mV/dec and ON/OFF ratio 107. Later, pH detection was conducted at room temperature, which showed an impressive sensitivity of ~880 by changing 1 unit of pH. We have also successfully shown Escherichia coli (E. coli) bacteria sensing from the suspended MoS2 transistor by functionalizing dielectric layer with E. coli antibodies. The reported biosensor has shown the ~9% of conductance changes with a lower concentration of E. coli (10 CFU/mL; colony-forming unit per mL) as well as maintain the constant sensitivity in three fabricated devices. The obtained enhancement in the sensitivity of devices and its effect on biomolecules detection can be extened to other biomolecules and this type of architecture has the potential to detect COVID-19 viruses based biomolecules.

Experimental Studies and Numerical Simulation of Polypyrrole Trilayer Actuators.

Conducting polymer actuators have shown wide application prospects in the field of biomedical sensors and micro-/nanorobotics. In order to explore more applications in biomedical sensing and robotics, it is essential to understand the actuator static behavior from an engineering perspective, before incorporating them into a design. In this article, we have established the mathematical model of a trilayer polypyrrole (PPy) cantilever actuator and validated it experimentally. The model helps in enhancing the efficiency and in improving the performance, predictability, and control of the actuator. The thermal expansion analogy, which is similar to volume change of the multilayer PPy actuator due to ion migration, has been considered to develop a mathematical model in COMSOL Multiphysics. To further validate the actuator deformation predicted by the mathematical modeling, a multilayer PPy actuator was fabricated by electrochemical synthesis and the experimentally determined deflection of the actuator was compared to simulation data. Both the theoretical and experimental results depict that the model is effective for predicting the bending behavior of multilayer PPy actuators at different input voltages.