[Dispensary-diagnostic department in the system of emergency surgical care]. / Konsul'tativno-diagnosticheskoe otdelenie v sisteme okazaniia ékstrennoé khirurgicheskoi pomoshchi.

3-year experience of dispensary-diagnostic department (DDD) working at the Center of emergency surgical care is analyzed. DDD activity consists of 2 types: dispensary-diagnostic and curative-prophylactic. Department has 5 beds where patients with indeterminate diagnosis are hospitalized (2737 patients over 3 years). Diagnostic beds permit to make diagnosis and select patients with parallel therapeutic procedures. 503 patients were discharged from DDD over 3 years. 534 patients were transferred to surgery department, 97 patients--in internal medicine department. 2% patients required 1-3 hours for final diagnosis, 17%--3-6 hours, 29%--12-24 hours, and only 4%--over twenty-four hours. In 1998--30% patients didn't require hospital treatment, in 1999--38.5%, in 2000--48.5%. A significant cost-effect was achieved.

[Reaction capabilities and structure of poly(rG) and poly(rG)-poly(rC) in solution by the method of the kinetics of hydrogen ion exchange]. / Issledovanie reaktsionnoi sposobnosti i struktury poli(rG) i poli(rG).poli(rC) v rastvore metodom kinetiki izotopnogo obmena vodoroda

Data on the kinetics of 1H greater than 3H exchange between water and C(8)H groups of guanylic residues in the poly(rG) and poly poly(rG)-poly(rC) are presented. Furthermore, optical properties (CD spectra and hyperchromism) of neutral solutions of these polymers from 20 to 100 degrees C are described. It is shown that the exchange in poly(rG) within the temperature range from 20 to 80 degrees C proceeds faster than in rGMP. Within the temperature range from 20 to 40 degrees C such an acceleration of the exchange is observed also in poly(rG)-poly(rC). According to the ylide mechanism of the exchange reaction the observed accleration of the exchanged in in C(8)H groups of guanylic residues is considered as a consequence of an increase of the positive charge at N(7) atoms. This effect is due to formation of additional hydrogen bonds in which N(7) atoms take part. The exchange in poly(rG)-poly(rG) at temperatures hihger than 75 degrees C, when these additional hydrogen bonds are absent, proceeds more slowly than in rGMP. Such picture is usual in other previously studied polynucleotides whose structure in solution is stabilized only by Watson - Crick hydrogen bonds and stacking interactions. The data obtained support a Guschelbauer's model of the four-stranded stranded poly(rG). They also indicate the posibility of associates formation in poly(rG)-poly(rC) solutions at temperature lower than 40 degrees C being stabilized by hydrogen bonds in which N(7) atoms of guanylic residues take part.

[Surgical treatment of post-thrombophlebitic disease]. / Khirurgicheskoe lechenie posttromboflebiticheskoi bolezni

A compression-functional test is recommended to determine indications to the Ascar-Zelenin operation and in selecting the optimum compression of crural muscles. The suggested complex of operative procedures involves: radical operation in the oval fossa region, partial of total removal of the great saphenous vein trunk, and, if indicated, also small saphenous vein, the Kocher and Crokett operation, duplication of the crural aponeurosis in the authors' modification with production of an additional dosaged pressure in the crural aponeurotic sheath. Late results followed up to 2 years were good and satisfactory in 94.4%, and poor--in 5.6% of the operated objects.