ABSTRACT
The purpose of this study was to assess the human papillomavirus (HPV) prevalence in cervical, oropharyngeal and anal samples of the high-risk population of Hungarian female sex workers (FSWs). HPV testing of swab specimens from FSWs (n = 34) using polymerase chain reaction (PCR) methodology was performed. Results were compared with control group (n = 52) matched for age. Questionnaires were used to obtain data regarding participants' sexual behaviour. Data were analysed using SPSS. HPV DNA was detected in at least one location in a great majority of FSWs (82.4%), compared with 46.2% of the general female population (P < 0.05). Both the cervical and the anal samples of sex workers showed higher infection rates than those of controls (64.7% vs. 34.6% and 50.0% vs. 15.4%, respectively, P < 0.05). High-risk HPV prevalence was also significantly higher in sex workers (55.9% vs. 25.0%, P < 0.05). A significantly higher proportion of FSWs had a history of genital warts (26.5% vs. 3.8%, P < 0.05). The results suggest that condom use may not result in adequate protection from HPV infection. The high infection rates among FSWs should be viewed as a priority group for HPV and cervical cancer prevention programmes since they are sources of HPV infection for the general population.
Subject(s)
Papillomavirus Infections/epidemiology , Sex Workers/statistics & numerical data , Sexually Transmitted Diseases, Viral/epidemiology , Adolescent , Adult , Anal Canal/virology , Case-Control Studies , Cervix Uteri/virology , DNA, Viral/analysis , Female , Genotype , Humans , Hungary/epidemiology , Middle Aged , Oropharynx/virology , Papillomaviridae/genetics , Prevalence , Risk Factors , Sexual Behavior/statistics & numerical data , Surveys and Questionnaires , Young AdultABSTRACT
A 10-year-old boy with vesicles and eroded lesions on his labia, oral mucosa, and trunk was diagnosed as having pemphigus vulgaris. The diagnosis was confirmed by histopathologic and immunofluorescence studies. The patient was successfully treated systemically with methylprednisolone and azathioprine. After 4.5 years the therapy was discontinued and the patient has had no relapse over the last 4 years.
Subject(s)
Lip Diseases/diagnosis , Pemphigus/diagnosis , Abdomen , Azathioprine/therapeutic use , Child , Diagnosis, Differential , Humans , Lip Diseases/drug therapy , Lip Diseases/pathology , Male , Methylprednisolone/therapeutic use , Mouth Mucosa , Pemphigus/drug therapy , Pemphigus/pathologyABSTRACT
We report on an asymmetric maculopapular exanthem of early childhood. One hundred eighty seven patients (111 girls, 76 boys) were examined over a four-year period, mainly in winter and spring. The first skin lesions appeared on the trunk or in the large flexures of the limbs. They spread centrifugally, often to the contralateral side, over two to four weeks, and disappeared with slight itching and moderate desquamation within another two to four weeks. Virologic studies were carried out in 34 cases; parainfluenzavirus 2, parainfluenzavirus 3, and adenoviral infection were diagnosed in two patients each. The chances of a causal relation between the viral infection and the skin symptoms were slight; only an incidental connection is likely to exist between the skin disorders and the viral infection.
