ABSTRACT
Inflammatory pseudotumor of the lymph nodes is a little-known condition characterized mainly by cervical lymph node enlargement, hematological manifestations, and major constitutional symptoms in most patients. The diagnosis is histological, after surgical removal of an involved lymph node. Histologically, stromal proliferation and neovascularity are present, as well as lymphocytic infiltration. This disease is considered benign because of its tendency toward spontaneous resolution, even though symptoms are usually intense. A male patient presented cervical lymph node enlargement, constitutional syndrome, and hematological manifestations, including oscillating thrombocytopenia, leukopenia, and increased ESR. The diagnosis was inflammatory pseudotumor of the lymph nodes, a rare disease. The evolution is torpid but the prognosis is good. This disease should be considered in the differential diagnosis of tumors of the neck region.
Subject(s)
Granuloma, Plasma Cell/pathology , Lymphatic Diseases/pathology , Aged , Diagnosis, Differential , Humans , Male , NeckABSTRACT
A randomized study was made of 125 patients with chronic middle ear infection. The most frequently isolated microorganisms were: Pseudomonas aeruginosa, Staphylococcus aureus and Enterobacteriaceae. Ciprofloxacin is very active against the microorganisms usually isolated and it has been shown to provide effective therapy in ear infections. In order to study the effectiveness of ciprofloxacin in chronic otitis media, we selected four different treatment groups: oral ciprofloxacin (500 mg/12 h); 0.5 and 0.2% topical solutions of ciprofloxacin (3 drops/8 h), and oral ciprofloxacin plus 0.2% topical solution. Topical polymyxin and neomycin were used as controls. Topical ciprofloxacin (0.2%) was the most effective regimen of those tested for the treatment of chronic otitis media.