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1.
Nurse Educ Today ; 27(6): 597-601, 2007 Aug.
Article in English | MEDLINE | ID: mdl-17081657

ABSTRACT

Psychological distress and poor adjustment among a significant number of nursing students is an important issue facing nursing education. The concerns need to be studied in detail and solutions need to be built into the nursing course in order to help students with such difficulty. This study used a cross-sectional survey design to study psychological distress, personality and adjustment among nursing students attending the College of Nursing, Christian Medical College, Vellore, India. One hundred and forty five nursing students were assessed using the General Health Questionnaire 12, the Eysenck Personality Questionnaire, and the Bell's Adjustment Inventory to investigate psychological distress, personality profile and adjustment, respectively. Thirty participants (20.7%) of the 145 students assessed reported high scores on the General Health Questionnaire. Psychological distress was significantly associated with having neurotic personality and adjustment difficulties in different areas of functioning.


Subject(s)
Adaptation, Psychological , Attitude of Health Personnel , Burnout, Professional/psychology , Personality , Social Adjustment , Students, Nursing/psychology , Adult , Analysis of Variance , Burnout, Professional/diagnosis , Burnout, Professional/epidemiology , Burnout, Professional/prevention & control , Chi-Square Distribution , Cross-Sectional Studies , Education, Nursing, Baccalaureate , Female , Health Services Needs and Demand , Humans , India/epidemiology , Linear Models , Logistic Models , Morbidity , Nursing Methodology Research , Personality Inventory , Risk Factors , Severity of Illness Index , Socioeconomic Factors , Surveys and Questionnaires
2.
Am J Psychiatry ; 163(3): 494-9, 2006 Mar.
Article in English | MEDLINE | ID: mdl-16513872

ABSTRACT

OBJECTIVE: Antipsychotic-induced erectile dysfunction is a significant clinical problem and is a common reason for poor medication compliance. This report studied the efficacy and tolerability of sildenafil citrate in patients with antipsychotic-induced erectile dysfunction. METHOD: The study design was a randomized, double-blind, placebo-controlled, flexible-dose, two-way crossover trial carried out at a tertiary referral center. Thirty-two married male outpatients with schizophrenia or delusional disorder and antipsychotic-induced erectile dysfunction were recruited for the trial. Sexual function was assessed from patient logs of sexual activity. RESULTS: Thirty-two subjects and their spouses, who agreed to take part in the study, were included in the crossover trial. Thirty-one (96.9%) completed the trial. There was no significant period effect or treatment-period interaction. Patients reported significant improvement while taking sildenafil in the number of adequate erections, satisfaction with sexual intercourse, and the duration of erections over 2 weeks. The odds ratios for adequate erections and for satisfactory sexual intercourse with sildenafil were 4.07 and 3.77, respectively. The effect of sildenafil remained significant even after adjustment for period and week effects and treatment-period interaction with Poisson regression analysis. There were no major side effects or adverse drug interactions. CONCLUSIONS: Sildenafil citrate is safe and effective in the treatment of antipsychotic-induced erectile dysfunction. It is also well tolerated.


Subject(s)
3',5'-Cyclic-GMP Phosphodiesterases/therapeutic use , Antipsychotic Agents/adverse effects , Erectile Dysfunction/chemically induced , Erectile Dysfunction/drug therapy , Piperazines/therapeutic use , Adult , Comorbidity , Cross-Over Studies , Dose-Response Relationship, Drug , Double-Blind Method , Drug Administration Schedule , Erectile Dysfunction/epidemiology , Follow-Up Studies , Humans , Male , Middle Aged , Placebos , Prolactin/blood , Purines , Regression Analysis , Schizophrenia/drug therapy , Schizophrenia/epidemiology , Schizophrenia, Paranoid/drug therapy , Schizophrenia, Paranoid/epidemiology , Schizophrenia, Paranoid/psychology , Sexual Behavior/psychology , Sildenafil Citrate , Sulfones , Treatment Outcome
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