Sex determination using mandibular anthropometric parameters in subadult Iranian samples.

INTRODUCTION: Sex determination is the first step in the identification of corpses and skeletal remains. The mandible is the largest and strongest bone of the face and has high durability. It is known that skeletal features vary by population, thus the need to establish population-specific standards. In this study, for the first time, we investigated mandibular anthropometric parameters for sex determination in subadult Iranian cadavers. METHODS: Eight mandibular anthropometric parameters were measured in 45 Iranian cadavers below the age of 20 (23 males and 22 females corpses), and the relationships of these variables with gender were determined. Collected data were analyzed using descriptive analysis, ROC curve, cross tabulation and discriminant analysis in SPSS 13. RESULTS: No significant statistical difference was seen in the mandibular anthropometric values between the two genders in samples below the age of 12. In the 12-19 age group, accuracy of symphysial height and bigonial breadth in differentiation of gender was 69% and 86.2% respectively. CONCLUSION: Although mandibular anthropometric parameters are not helpful in sex determination below the age of 12, if for some reasons such as explosions, air disasters and other accidents, only the mandible is available, symphysial height and mandibular bigonial breadth could be used to determine the gender with high accuracy.

Is there a role for progesterone in the management of acute organophosphate poisoning during pregnancy?

Organophosphates are commonly used pesticides and cause about one million unintentional and 2 million suicidal exposures with up to 300,000 fatalities every year around the world. Toxicity of organophosphates is due to inhibition cholinesterase activity and prolonging the effects of acetylcholine in the receptor site. Clinical features of organophosphate poisoning are defecation, urination, miosis, bronchorrhea, emesis, lacrimation and salivation. Spontaneous abortion reported some when in pregnant patients. Intravenous administration of benzodiazepines, atropine and pralidoxime is the formal treatment of this toxicity. Atropine and pralidoxime have been assigned to pregnancy class C by the FDA and should be recommended for use in pregnant women clinically suffer organophosphate poisoning. Benzodiazepines have been assigned to pregnancy class D and should be avoided during pregnancy. Clinical experiments suggest transplacental transfer of organophosphates is possible, and fetal sensitivity is probable, but a single acute overdose most likely don't make any physical deformities, therefore termination of pregnancy is not imperative. Nonetheless, no definite strategy focused on maintaining pregnancy. Here we propose an idea that in any female case of acute organophosphate poisoning in childbearing range of age, maternal serum Beta-HCG should be tested for pregnancy and prophylactic progesterone should be used in pregnant cases of organophosphate poisoning.