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2.
3.
Vopr Onkol ; 45(1): 72-6, 1999.
Article in Russian | MEDLINE | ID: mdl-10941371

ABSTRACT

6,212 lung cancer patients have been examined and treated. The data on surgical and combined treatment of 2,702 patients have been analyzed. Postoperative complication incidence has dropped to 5.4% in recent years. End results have improved due to use of organ-saving, reconstructive and plastic procedures for the bronchi and trachea in conjunction with radiotherapy.


Subject(s)
Lung Neoplasms/radiotherapy , Lung Neoplasms/surgery , Adult , Aged , Female , Humans , Incidence , Male , Middle Aged , Postoperative Complications/etiology , Radiotherapy, Adjuvant , Retrospective Studies , Survival Analysis , Treatment Outcome
5.
Vopr Onkol ; 41(1): 75-8, 1995.
Article in Russian | MEDLINE | ID: mdl-7667949

ABSTRACT

The study group included 2161 patients operated on in 1968-1990. Tumors stage I were morphologically confirmed in 910 cases (T1S-3, T1-375 and T2-532). 827 patients survived 5 years (90.9%); 551 patients-10 years (60.3%). Primary multiple neoplasms (PMN) of different localization were detected in 96 (10.6%) patients with stage I tumors. Thirteen patients (13.5%) died of progression of a second tumor; 17 (17%)-of other causes. Average 5-year survival was 65%, 10 years-53%. These indices in 96 patients with PMNs were 73 and 53%, respectively. Relative risk of PMN in lung cancer was found to be in direct correlation with survival time and to depend, to a large degree, on tumor extension. When PMNs are detected early and treated radically, new primary tumors emergence does not significantly in lung cancer stage I. Preliminary results showed chemotherapy (neoadjuvant one included) to lower the risk of PMN in lung cancer stage I. The most plausible causes of enhanced survival of patients with PMNs are discussed.


Subject(s)
Lung Neoplasms/mortality , Lung Neoplasms/pathology , Neoplasms, Multiple Primary/mortality , Neoplasms, Multiple Primary/pathology , Female , Humans , Lung Neoplasms/therapy , Male , Middle Aged , Neoplasm Staging , Neoplasms, Multiple Primary/therapy , Survival Analysis
6.
Klin Med (Mosk) ; 71(3): 34-6, 1993.
Article in Russian | MEDLINE | ID: mdl-8015212

ABSTRACT

The paper presents concentrations of atrial sodium-uretic hormone (AH) in the plasma of hypertensive subjects during a hypertensive crisis and in stable blood pressure, in healthy subjects (12, 19 and 7 females, respectively). AH levels were the highest in hypertensives in the crisis. Mean AH concentrations in the crisis and short after the pressure normalization did not differ much. Mechanisms of these phenomena are discussed, relations between AH levels, clinical and hemodynamic characteristics of hypertensive crises are considered.


Subject(s)
Atrial Natriuretic Factor/blood , Hypertension/blood , Aged , Blood Pressure , Female , Hemodynamics , Humans , Hypertension/physiopathology , Middle Aged
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