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Radiats Biol Radioecol ; 34(2): 236-9, 1994.
Article in Russian | MEDLINE | ID: mdl-8193714

ABSTRACT

It has been studied the influence of translam-beta-1,3; 1,6-glucan, extracted from seaweed Laminaria, on the isolation of E. coli from spleen and on the functional activity of peritoneal macrophages of sublethal irradiated and infected mice. It has been shown the reduction of the number of microbes, isolated from spleen and stimulation of ingestive and digestive activity of macrophages following the introduction of translam in mice. This results show about the increase of natural resistance of irradiated organism under translam action and characterise this glucan as effective stimulator of immunity.


Subject(s)
Adjuvants, Immunologic/therapeutic use , Glucans/therapeutic use , Radiation Injuries, Experimental/drug therapy , Radiation-Protective Agents/therapeutic use , Animals , Drug Evaluation, Preclinical , Escherichia coli Infections/drug therapy , Escherichia coli Infections/immunology , Gamma Rays , Immunity, Innate/drug effects , Laminaria , Mice , Phagocytosis/drug effects , Radiation Injuries, Experimental/complications , Radiation Injuries, Experimental/immunology , Time Factors
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