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Acta Neurol Belg ; 121(6): 1463-1468, 2021 Dec.
Article in English | MEDLINE | ID: mdl-32246319

ABSTRACT

Wide-spread visualization methods which are computed tomography (CT) and magnetic resonance imaging (MRI) are not sensitive to mild traumatic brain injury (mTBI). However, mTBI may cause changes of cerebral microstructure that could be found using diffusion-tensor imaging. The aim of this study is to reveal the impact of acute mTBI (no more than 3 days after trauma) on diffusion parameters in corpus callosum, corticospinal tract, and thalamus in children (aged 14-18). Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were analyzed. Significant increase in FA and decrease in ADC were observed in thalamus. The trend to an increase in FA is observed in corpus callosum.


Subject(s)
Brain Concussion/diagnostic imaging , Corpus Callosum/diagnostic imaging , Diffusion Tensor Imaging/trends , Thalamus/diagnostic imaging , Water , Adolescent , Anisotropy , Brain Concussion/metabolism , Child , Corpus Callosum/metabolism , Diffusion , Diffusion Tensor Imaging/methods , Female , Humans , Male , Thalamus/metabolism , Water/metabolism
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