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1.
Panel backs new NIH center devoted to translational medicine.
Vastag, Brian.
Nat Med ; 17(1): 5, 2011 Jan.
Article in English | MEDLINE | ID: mdl-21217653

Subject(s)
National Institutes of Health (U.S.) , Rare Diseases/therapy , Translational Research, Biomedical/trends , Humans , National Institute of Allergy and Infectious Diseases (U.S.) , United States
2.
Biotechnology: Crossing the barrier.
Vastag, Brian.
Nature ; 466(7309): 916-8, 2010 Aug 19.
Article in English | MEDLINE | ID: mdl-20725015

Subject(s)
Blood-Brain Barrier/metabolism , Brain Diseases/drug therapy , Proteins/pharmacokinetics , Proteins/therapeutic use , Animals , Catheters, Indwelling , Clinical Trials as Topic , Glial Cell Line-Derived Neurotrophic Factor/administration & dosage , Glial Cell Line-Derived Neurotrophic Factor/pharmacokinetics , Glial Cell Line-Derived Neurotrophic Factor/therapeutic use , Humans , Injections, Intraventricular , Neurturin/administration & dosage , Neurturin/genetics , Neurturin/therapeutic use , Parkinson Disease/drug therapy , Proteins/administration & dosage , Proteins/adverse effects
3.
New trial data do not end the PSA screening debate.
Vastag, Brian.
J Natl Cancer Inst ; 101(12): 844-5, 2009 Jun 16.
Article in English | MEDLINE | ID: mdl-19509364

Subject(s)
Mass Screening , Prostate-Specific Antigen/blood , Prostatic Neoplasms/immunology , Prostatic Neoplasms/mortality , Adult , Age Factors , Aged , Androgen Antagonists/adverse effects , Antineoplastic Agents, Hormonal/adverse effects , Clinical Trials as Topic , Comorbidity , Decision Making , Europe/epidemiology , Humans , Male , Mass Screening/adverse effects , Mass Screening/methods , Mass Screening/standards , Middle Aged , Patient Participation , Prostatectomy/adverse effects , Prostatic Neoplasms/therapy , Time Factors , United States/epidemiology
4.
Nutrients for prevention: negative trials send researchers back to drawing board.
Vastag, Brian.
J Natl Cancer Inst ; 101(7): 446-8, 451, 2009 Apr 01.
Article in English | MEDLINE | ID: mdl-19318633

Subject(s)
Micronutrients/pharmacology , Neoplasms/prevention & control , Calcium/pharmacology , Clinical Trials as Topic , Folic Acid/pharmacology , Food-Drug Interactions , Humans , Research Design , Selenium/pharmacology , Trace Elements/pharmacology , Treatment Failure , Vitamin B 12/pharmacology , Vitamin B 6/pharmacology , Vitamin D/pharmacology , Vitamin E/pharmacology , Vitamins/pharmacology , beta Carotene/pharmacology
5.
Frontiers in science. How did life on Earth get started?
Vastag, Brian.
US News World Rep ; 145(3): 43-4, 2008.
Article in English | MEDLINE | ID: mdl-18756666

Subject(s)
Earth, Planet , Science
6.
Frontiers in science. Will we soon find life in the heavens?
Vastag, Brian.
US News World Rep ; 145(3): 50, 52, 2008.
Article in English | MEDLINE | ID: mdl-18756669

Subject(s)
Life , Science , Space Flight
7.
Preventing prostate cancer: new analyses put finasteride back on the map.
Vastag, Brian.
J Natl Cancer Inst ; 100(16): 1132-3, 2008 Aug 20.
Article in English | MEDLINE | ID: mdl-18695128

Subject(s)
Anticarcinogenic Agents , Carcinogens , Finasteride , Prostatic Neoplasms/chemically induced , Prostatic Neoplasms/prevention & control , 5-alpha Reductase Inhibitors , Anticarcinogenic Agents/administration & dosage , Anticarcinogenic Agents/adverse effects , Azasteroids/therapeutic use , Bias , Biopsy, Needle , Confounding Factors, Epidemiologic , Drug Approval , Dutasteride , Enzyme Inhibitors/administration & dosage , Enzyme Inhibitors/adverse effects , Finasteride/administration & dosage , Finasteride/adverse effects , Humans , Incidence , Male , Patents as Topic , Prostatic Hyperplasia/drug therapy , Prostatic Neoplasms/epidemiology , Prostatic Neoplasms/pathology , Severity of Illness Index , United States/epidemiology , United States Food and Drug Administration
8.
Unproven treatments.
Vastag, Brian.
US News World Rep ; 144(13): 50, 2008 May 12.
Article in English | MEDLINE | ID: mdl-18655696

Subject(s)
Adult Stem Cells/transplantation , Humans , Quackery , Quality of Health Care/standards
9.
Assembly work.
Vastag, Brian.
Nature ; 453(7193): 422-3, 2008 May 15.
Article in English | MEDLINE | ID: mdl-18574870

Subject(s)
Education, Graduate , Research Personnel/education , Research/education , Education, Graduate/trends , Group Processes , Humans , Internationality , Research/trends , Workforce
10.
RNA interference provides new approach for finding cancer genes.
Vastag, Brian.
J Natl Cancer Inst ; 100(11): 766-7, 2008 Jun 04.
Article in English | MEDLINE | ID: mdl-18505959

Subject(s)
Genes, Neoplasm , RNA Interference , Animals , Breast Neoplasms/genetics , Female , Humans , I-kappa B Kinase/genetics , Male
11.
EPA feels heat over flame retardant.
Vastag, Brian.
Nature ; 452(7187): 513, 2008 Apr 03.
Article in English | MEDLINE | ID: mdl-18385696

Subject(s)
Flame Retardants/adverse effects , Flame Retardants/toxicity , Phenyl Ethers/adverse effects , Phenyl Ethers/toxicity , Polybrominated Biphenyls/adverse effects , Polybrominated Biphenyls/toxicity , United States Environmental Protection Agency/legislation & jurisprudence , Animals , Brain/drug effects , Brain/embryology , Conflict of Interest/legislation & jurisprudence , Drug Approval , Halogenated Diphenyl Ethers , Hazardous Substances/adverse effects , Hazardous Substances/toxicity , Humans , Maine , United States , United States Environmental Protection Agency/ethics
12.
Reviewer leaked Avandia study to drug firm.
Vastag, Brian.
Nature ; 451(7178): 509, 2008 Jan 31.
Article in English | MEDLINE | ID: mdl-18235464

Subject(s)
Diabetes Mellitus/drug therapy , Drug Industry , Myocardial Infarction/chemically induced , Peer Review, Research/ethics , Thiazolidinediones/adverse effects , Truth Disclosure , Drug Industry/economics , Ethics, Professional , Humans , Meta-Analysis as Topic , Rosiglitazone , Thiazolidinediones/economics , Thiazolidinediones/therapeutic use , Truth Disclosure/ethics
13.
Soy and prostate cancer study results mixed.
Vastag, Brian.
J Natl Cancer Inst ; 99(18): 1364-5, 2007 Sep 19.
Article in English | MEDLINE | ID: mdl-17848664

Subject(s)
Anticarcinogenic Agents/pharmacology , Feeding Behavior , Phytoestrogens/pharmacology , Prostatic Neoplasms/epidemiology , Prostatic Neoplasms/prevention & control , Soy Foods , Equol , Genistein/pharmacology , Humans , Intestines/microbiology , Isoflavones/metabolism , Isoflavones/pharmacology , Japan/epidemiology , Male , Phytoestrogens/metabolism
14.
Telemedicine's adolescent angst.
Vastag, Brian.
Hosp Health Netw ; 81(6): 66, 68, 70, 2007 Jun.
Article in English | MEDLINE | ID: mdl-17695169

ABSTRACT

Ten years after telemedicine hit the mainstream, growing pains are evident, robotic surgery and other "wows" relatively rare. But home-based care is set to explode.


Subject(s)
Diffusion of Innovation , Robotics/trends , Telemedicine/trends , Fiber Optic Technology/instrumentation , Home Care Services , Humans , Insurance, Health, Reimbursement , Licensure, Medical , Monitoring, Ambulatory/instrumentation , Robotics/instrumentation , Specialties, Surgical/instrumentation , Specialties, Surgical/trends , Telemedicine/economics , Telemedicine/instrumentation , United States , United States Agency for Healthcare Research and Quality , United States National Aeronautics and Space Administration
15.
US aims to tighten rules on direct-to-consumer drug ads.
Vastag, Brian.
Nat Biotechnol ; 25(3): 267, 2007 Mar.
Article in English | MEDLINE | ID: mdl-17344868

Subject(s)
Advertising/legislation & jurisprudence , Consumer Behavior , Drug Industry/legislation & jurisprudence , Legislation, Drug , Humans , Policy Making , Politics , United States , United States Food and Drug Administration/legislation & jurisprudence
16.
H&HN--eight decades of health care: 80th anniversary. CIOs input key to creating seamless infrastructures.
Vastag, Brian.
Hosp Health Netw ; 81(2): 16, 2007 Feb.
Article in English | MEDLINE | ID: mdl-17380609

Subject(s)
Biomedical Engineering/organization & administration , Computer Communication Networks/organization & administration , Equipment and Supplies/standards , Hospital Information Systems/organization & administration , Information Management/trends , Professional Role , Systems Integration , Interdepartmental Relations , Purchasing, Hospital/trends , United States
17.
Patient care. A new way of treating today's wounded soldiers.
Vastag, Brian S.
Hosp Health Netw ; 81(1): 16, 2007 Jan.
Article in English | MEDLINE | ID: mdl-17302127

Subject(s)
Hospitals, Veterans/organization & administration , Multiple Trauma/epidemiology , Multiple Trauma/rehabilitation , Trauma Centers/organization & administration , Warfare , Blast Injuries/epidemiology , Blast Injuries/therapy , Humans , Iraq , United States/epidemiology , United States Department of Veterans Affairs
18.
The policy outlook from the Hill.
Vastag, Brian.
Nat Biotechnol ; 25(1): 13-6, 2007 Jan.
Article in English | MEDLINE | ID: mdl-17211381

Subject(s)
Biotechnology/economics , Biotechnology/legislation & jurisprudence , Drug Industry/economics , Drug Industry/legislation & jurisprudence , Federal Government , Public Policy , United States
19.
US marijuana laws clamping the lid on pot research.
Vastag, Brian.
Nat Med ; 12(12): 1335, 2006 Dec.
Article in English | MEDLINE | ID: mdl-17151675

Subject(s)
Drug and Narcotic Control/legislation & jurisprudence , Legislation, Drug , Marijuana Smoking/legislation & jurisprudence , California , Federal Government , Humans , State Government
20.
HSP-90 inhibitors promise to complement cancer therapies.
Vastag, Brian.
Nat Biotechnol ; 24(11): 1307, 2006 Nov.
Article in English | MEDLINE | ID: mdl-17093460

Subject(s)
HSP90 Heat-Shock Proteins/antagonists & inhibitors , Neoplasms/drug therapy , Benzoquinones/pharmacology , Clinical Trials as Topic , Drug Industry , Enzyme Inhibitors/pharmacology , Humans , Lactams, Macrocyclic/pharmacology
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