ABSTRACT
The present study introduces an active macroscopic mixing device for aqueous sanitizer preparation. It operates on a piezoelectrically actuated oscillating cantilever beam appropriate for disparate feature liquid-liquid mixing. A piezoelectric actuated cantilever beam at the third bending mode vibration frequency produces extreme vibrations when excited by a suitable voltage. Potent mixing occurs as the robust vibration energy is sent from the beam to the container's test liquid. In this work, different glycerol concentrations were mixed with deionized (DI) water and ethanol at 25 â. The mixer's performance to mix DI water-glycerol, ethanol-glycerol, and DI water-ethanol-glycerol considered a sanitizer was tested. The sanitizer mixture's measured density, viscosity, and surface tension values were 0.7502 g cm-3, 1.8906 cp, 34.7893 dyne cm-1, respectively. The measured aqueous-based glycerol mixture's density and viscosity values were validated with the computed values by previous researcher's models and formulas. The observed density reading of the aqueous-based 25% glycerol concentration mixture agreed with the estimated value of a density model having ± 1.1290% deviation. Supplementary Information: The online version contains supplementary material available at 10.1007/s11696-021-01886-3.
Subject(s)
Acidosis, Lactic , Pyruvate Dehydrogenase (Lipoamide)/genetics , Pyruvate Dehydrogenase Complex Deficiency Disease , Acidosis, Lactic/etiology , Acidosis, Lactic/genetics , Exons/genetics , Heterozygote , Humans , Infant , Mutation , Pyruvate Dehydrogenase Complex Deficiency Disease/diagnosis , Pyruvate Dehydrogenase Complex Deficiency Disease/geneticsABSTRACT
OBJECTIVES: To document the epidemiological, clinical and laboratory profile of all children with scrub typhus at a tertiary care centre in Chennai between September 2010 and June 2011. METHODS: The case records of all children admitted and diagnosed with scrub typhus between September 2010 and June 2011 were analysed to look for salient clinical and laboratory parameters. RESULTS: During the study period, 52 children were admitted with scrub typhus in the authors' hospital. The presenting complaints included fever in all cases. Other symptoms included swelling of legs (50 %) and vomiting (45 %). 13 % presented with CNS symptoms. The commonest physical findings included eschar (67 %), hepatomegaly (94 %), splenomegaly (73 %) and third spacing (67 %). Salient lab parameters included packed cell volume (PCV) <30 (48 %), leucocytosis (56 %), positive C-reactive protein (CRP) (92 %), hypoalbuminemia (79 %). Common complications included acute kidney injury (10 %) and peripheral gangrene (4 %). There was no mortality in the present case series. CONCLUSIONS: The clinical profile of children with scrub typhus in a tertiary care centre is reported. Eschar and hepatosplenomegaly with a high CRP value is helpful in diagnosis. All patients responded well to the treatment.
