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Phys Med Biol ; 64(24): 245007, 2019 12 13.
Article in English | MEDLINE | ID: mdl-31652422

ABSTRACT

The Sculptura™ is a new high-dose-rate electronic brachytherapy system developed by Sensus Healthcare. By combining a steerable electron beam with a partitioned diamond-tungsten x-ray target, the x-ray source of the Sculptura™ is capable of producing highly anisotropic dose distributions, thus achieving true 3D beam directionality. This article reports the spectral and dosimetric characterization of the Sculptura™ x-ray source through a combination of measurements and Monte Carlo simulations for operating points between 50-100 kV. Excellent agreement (~5% discrepancy) between the simulations and measurements was obtained for in-air dose rate characterization. The validated simulations were then used to calculate the dose distribution in water. Dose rates of >2 cGy/min/µA can be produced at 100 kV, thus delivering 10 Gy in 1 min for typical operating conditions. The dose distributions are sharply peaked, with a full-width at half-maximum azimuth of about 100°.


Subject(s)
Brachytherapy/instrumentation , Brachytherapy/methods , Diamond , Electronics , Electrons , Humans , Monte Carlo Method , Radiometry , Radiotherapy Dosage , Tungsten , X-Rays
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