ABSTRACT
Epidemiologic studies have suggested that vagotomy increases subsequent colorectal cancer risk. This hypothesis was investigated in the rat 1,2 dimethylhydrazine (DMH) colorectal carcinogenesis model. Eighty-five rats were divided into four groups having either truncal vagotomy and Heineke-Mickulicz pyloroplasty, pyloroplasty alone, laparotomy alone, and anesthesia alone. After recovery from the procedures, colon tumors were induced with five injections of DMH. Results of carcinogenesis show a trend towards increased incidence and yield of colorectal and duodenal tumors after vagotomy, though this was not statistically significant, perhaps because the high postoperative mortality from vagotomy diminished the power of the study.
Subject(s)
Colorectal Neoplasms/etiology , Pylorus/surgery , Vagotomy/adverse effects , 1,2-Dimethylhydrazine , Analysis of Variance , Animals , Body Weight , Carcinogens , Colorectal Neoplasms/chemically induced , Dimethylhydrazines , Male , Postoperative Complications , Random Allocation , Rats , Rats, Sprague-Dawley , Risk FactorsABSTRACT
Experience with 43 duodenoplasties as a complementary procedure of proximal gastric vagotomy used in peptic duodenal stenosis was reviewed. After a rigid protocol aimed at treating the metabolic imbalance, gastric dilation, and activity of the ulcer, the cases were very similar to elective ones. Two types of duodenoplasty were most commonly employed: anterior duodenectomy with a transverse duodenorrhaphy (26 cases) and Finney's duodenoplasty (15 cases). No deaths or serious complications were reported. The only operative accident was a splenic lesion with splenectomy. Two recurrences were observed. The patients were followed up from January 1978.
Subject(s)
Duodenal Obstruction/surgery , Duodenum/surgery , Peptic Ulcer/surgery , Vagotomy, Proximal Gastric , Duodenal Obstruction/etiology , Female , Humans , Male , Methods , Peptic Ulcer/complications , Postoperative Complications , Vagotomy, Proximal Gastric/methodsABSTRACT
Os autores tecem comentarios a respeito da necessidade de uma sistematizacao no atendimento extra-hospitalar do politraumatizado e, em particular, do traumatizado de torax e do abdome. Enfantizam a necessidade de um melhor treinamento para todos aqueles que se propoem a esse tipo de atendimento, alem das melhorias das ambulancias no tocante a seus recursos terapeuticos disponiveis.Chamam tambem atencao quanto a importancia da comunicacao, em tadas as fases do atendimento, do medico com o setor de emergencia
