Variability in the Relationship Between Velocity Loss and Percentage of Completed Repetitions During Horizontal Leg Press and Bench Press in Postmenopausal Women.

ABSTRACT: Iglesias-Soler, E, Rial-Vázquez, J, Nine, I, Fariñas, J, Revuelta-Lera, B, and García-Ramos, A. Variability in the relationship between velocity loss and percentage of completed repetitions during horizontal leg press and bench press in postmenopausal women. J Strength Cond Res XX(X): 000-000, 2024-This study aimed to analyze the intersubject variability in the relationship between percentage of velocity loss (%VL) and percentage of repetitions performed out of maximum possible (%MNR) in postmenopausal women. Thirty-five postmenopausal active women (58 ± 3 years) performed sets leading to muscular failure, completing 10-13 repetitions, in both leg press (LP) and bench press (BP). Mean lift velocity of each repetition was expressed as a percentage of the fastest repetition, and repetitions were quantified as a percentage of the maximum number of repetitions completed in the set. Given the hierarchical structure of the data, %VL-%MNR relationships were fitted by linear mixed model regressions. A significant intersubject variability in the intercept (i.e., %MNR associated with 0%VL) was detected (p < 0.001 in both LP and BP), even when centered values of the completed repetitions were included in the models. The estimated variance in the intercept for LP (117.39; SE: 45.41) was almost double that for BP (67.47; SE: 20.27). The variability observed in the intercept entailed variability in the estimated %MNR for specific %VL values. The use of velocity loss thresholds for estimating the intensity of effort in active postmenopausal women does not overcome uncertainty of more traditional methods.

Are Young Female Basketball Players Adequately Prepared for a Force-Velocity Jumping and Sprinting Assessment?

PURPOSE: The aim of this study was to explore the interday reliability of mechanical variables obtained from the horizontal and vertical force-velocity (FV) profiles in adolescent female basketball players. If found to be reliable, the associations between FV parameters (theoretical maximal force, velocity, and power), squat jump (SJ) height, 30-m sprint, and change of direction (COD) times were evaluated. METHODS: After familiarization, SJ against incremental loads, 30-m sprint, and 505-COD tests were obtained twice in 36 adolescent female basketball players (age = 15.4 [1.2] y). RESULTS: Reliability for vertical FV parameters was unacceptable, whereas 505-COD times and FV horizontal parameters (except for theoretical maximal power) showed a moderate to high reliability. 505-COD time was correlated with FV horizontal parameters (range: r = -.821, -.451), and a large association was observed with both SJ height (r = -.678, -.600) and 30-m sprint time (r = .813, .858). CONCLUSIONS: Due to low levels of strength, our athletes were not adequately prepared to obtain a reliable vertical FV profile. Practitioners can expect acceptable reliability of the horizontal FV profile. Given the association between COD performance and SJ height and 30-m sprint time, we encouraged practitioners with limited equipment at their disposal to use COD and/or 30-m sprint tests.

Outcome prioritization and preferences among older adults with cancer starting chemotherapy in a randomized clinical trial.

INTRODUCTION: Older adults with cancer facing competing treatments must prioritize between various outcomes. This study assessed health outcome prioritization among older adults with cancer starting chemotherapy. METHODS: Secondary analysis of a randomized trial addressing vulnerabilities in older adults with cancer. Patients completed three validated outcome prioritization tools: 1) Health Outcomes Tool: prioritizes outcomes (survival, independence, symptoms) using a visual analog scale; 2) Now vs. Later Tool: rates the importance of quality of life at three times-today versus 1 or 5 years in the future; and 3) Attitude Scale: rates agreement with outcome-related statements. The authors measured the proportion of patients prioritizing various outcomes and evaluated their characteristics. RESULTS: A total of 219 patients (median [range] age 71 [65-88], 68% with metastatic disease) were included. On the Health Outcomes Tool, 60.7% prioritized survival over other outcomes. Having localized disease was associated with choosing survival as top priority. On the Now vs. Later Tool, 50% gave equal importance to current versus future quality of life. On the Attitude Scale, 53.4% disagreed with the statement "the most important thing to me is living as long as I can, no matter what my quality of life is"; and 82.2% agreed with the statement "it is more important to me to maintain my thinking ability than to live as long as possible". CONCLUSION: Although survival was the top priority for most participants, some older individuals with cancer prioritize other outcomes, such as cognition and function. Clinicians should elicit patient-defined priorities and include them in decision-making.

Development of an automated amplicon-based next-generation sequencing pipeline for rapid detection of bacteria and fungi directly from clinical specimens.

The timely identification of microbial pathogens is essential to guide targeted antimicrobial therapy and ultimately, successful treatment of an infection. However, the yield of standard microbiology testing (SMT) is directly related to the duration of antecedent antimicrobial therapy as SMT culture methods are dependent on the recovery of viable organisms, the fastidious nature of certain pathogens, and other pre-analytic factors. In the last decade, metagenomic next-generation sequencing (mNGS) has been successfully utilized as a diagnostic tool for various applications within the clinical laboratory. However, mNGS is resource, time, and labor-intensive-requiring extensive laborious preliminary benchwork, followed by complex bioinformatic analysis. We aimed to address these shortcomings by developing a largely Automated targeted Metagenomic next-generation sequencing (tmNGS) PipeLine for rapId inFectIous disEase Diagnosis (AMPLIFIED) to detect bacteria and fungi directly from clinical specimens. Therefore, AMPLIFIED may serve as an adjunctive approach to complement SMT. This tmNGS pipeline requires less than 1 hour of hands-on time before sequencing and less than 2 hours of total processing time, including bioinformatic analysis. We performed tmNGS on 50 clinical specimens with concomitant cultures to assess feasibility and performance in the hospital laboratory. Of the 50 specimens, 34 (68%) were from true clinical infections. Specimens from cases of true infection were more often tmNGS positive compared to those from the non-infected group (82.4% vs 43.8%, respectively, P = 0.0087). Overall, the clinical sensitivity of AMPLIFIED was 54.6% with 85.7% specificity, equating to 70.6% and 75% negative and positive predictive values, respectively. AMPLIFIED represents a rapid supplementary approach to SMT; the typical time from specimen receipt to identification of potential pathogens by AMPLIFIED is roughly 24 hours which is markedly faster than the days, weeks, and months required to recover bacterial, fungal, and mycobacterial pathogens by culture, respectively. IMPORTANCE: To our knowledge, this represents the first application of an automated sequencing and bioinformatics pipeline in an exclusively pediatric population. Next-generation sequencing is time-consuming, labor-intensive, and requires experienced personnel; perhaps contributing to hesitancy among clinical laboratories to adopt such a test. Here, we report a strong case for use by removing these barriers through near-total automation of our sequencing pipeline.

Corrigendum: Deciphering decidual leukocyte traffic with serial intravascular staining.

[This corrects the article DOI: 10.3389/fimmu.2023.1332943.].

Decidual leukocytes respond to African lineage Zika virus infection with mild anti-inflammatory changes during acute infection in rhesus macaques.

Zika virus (ZIKV) can be vertically transmitted during pregnancy resulting in a range of adverse pregnancy outcomes. The decidua is commonly found to be infected by ZIKV, yet the acute immune response to infection remains understudied in vivo. We hypothesized that in vivo African-lineage ZIKV infection induces a pro-inflammatory response in the decidua. To test this hypothesis, we evaluated the decidua in pregnant rhesus macaques within the first two weeks following infection with an African-lineage ZIKV and compared our findings to gestationally aged-matched controls. Decidual leukocytes were phenotypically evaluated using spectral flow cytometry, and cytokines and chemokines were measured in tissue homogenates from the decidua, placenta, and fetal membranes. The results of this study did not support our hypothesis. Although ZIKV RNA was detected in the decidual tissue samples from all ZIKV infected dams, phenotypic changes in decidual leukocytes and differences in cytokine profiles suggest that the decidua undergoes mild anti-inflammatory changes in response to that infection. Our findings emphasize the immunological state of the gravid uterus as a relatively immune privileged site that prioritizes tolerance of the fetus over mounting a pro-inflammatory response to clear infection.

Adeno-Associated Virus Type 9-Mediated Gene Therapy of Choline Acetyltransferase-Deficient Mice.

The enzyme choline acetyltransferase (ChAT) synthesizes acetylcholine from acetyl-CoA and choline at the neuromuscular junction and at the nerve terminals of cholinergic neurons. Mutations in the ChAT gene (CHAT) result in a presynaptic congenital myasthenic syndrome (CMS) that often associates with life-threatening episodes of apnea. Knockout mice for Chat (Chat-/-) die at birth. To circumvent the lethality of this model, we crossed mutant mice possessing loxP sites flanking Chat exons 4 and 5 with mice that expressed Cre-ERT2. Injection of tamoxifen (Tx) at postnatal (P) day 11 in these mice induced downregulation of Chat, autonomic failure, weakness, and death. However, a proportion of Chatflox/flox-Cre-ERT2 mice receiving at birth an intracerebroventricular injection of 2 × 1013 vg/kg adeno-associated virus type 9 (AAV9) carrying human CHAT (AAV9-CHAT) survived a subsequent Tx injection and lived to adulthood without showing signs of weakness. Likewise, injection of AA9-CHAT by intracisternal injection at P28 after the onset of weakness also resulted in survival to adulthood. The expression of Chat in spinal motor neurons of Chatflox/flox-Cre-ERT2 mice injected with Tx was markedly reduced, but AAV-injected mice showed a robust recovery of ChAT expression, which was mainly translated by the human CHAT RNA. The biodistribution of the viral genome was widespread but maximal in the spinal cord and brain of AAV-injected mice. No significant histopathological changes were observed in the brain, liver, and heart of AAV-injected mice after 1 year follow-up. Thus, AAV9-mediated gene therapy may provide an effective and safe treatment for patients severely affected with CHAT-CMS.

Cotyledon-Specific Flow Evaluation of Rhesus Macaque Placental Injury Using Ferumoxytol Dynamic Contrast-Enhanced MRI.

BACKGROUND: Recently, dynamic contrast-enhanced (DCE) MRI with ferumoxytol as contrast agent has recently been introduced for the noninvasive assessment of placental structure and function throughout. However, it has not been demonstrated under pathological conditions. PURPOSE: To measure cotyledon-specific rhesus macaque maternal placental blood flow using ferumoxytol DCE MRI in a novel animal model for local placental injury. STUDY TYPE: Prospective animal model. SUBJECTS: Placental injections of Tisseel (three with 0.5 mL and two with 1.5 mL), monocyte chemoattractant protein 1 (three with 100 µg), and three with saline as controls were performed in a total of 11 rhesus macaque pregnancies at approximate gestational day (GD 101). DCE MRI scans were performed prior (GD 100) and after (GD 115 and GD 145) the injection (term = GD 165). FIELD STRENGTH/SEQUENCE: 3 T, T1-weighted spoiled gradient echo sequence (product sequence, DISCO). ASSESSMENT: Source images were inspected for motion artefacts from the mother or fetus. Placenta segmentation and DCE processing were performed for the dynamic image series to measure cotyledon specific volume, flow, and normalized flow. Overall placental histopathology was conducted for controls, Tisseel, and MCP-1 animals and regions of tissue infarctions and necrosis were documented. Visual inspections for potential necrotic tissue were conducted for the two Tisseelx3 animals. STATISTICAL TESTS: Wilcoxon rank sum test, significance level P < 0.05. RESULTS: No motion artefacts were observed. For the group treated with 1.5 mL of Tisseel, significantly lower cotyledon volume, flow, and normalized flow per cotyledon were observed for the third gestational time point of imaging (day ~145), with mean normalized flow of 0.53 minute-1 . Preliminary histopathological analysis shows areas of tissue necrosis from a selected cotyledon in one Tisseel-treated (single dose) animal and both Tisseelx3 (triple dose) animals. DATA CONCLUSION: This study demonstrates the feasibility of cotyledon-specific functional analysis at multiple gestational time points and injury detection in a placental rhesus macaque model through ferumoxytol-enhanced DCE MRI. LEVEL OF EVIDENCE: NA TECHNICAL EFFICACY: Stage 2.

Sedentary behavior and physical inactivity from a comprehensive perspective.

OBJECTIVE: To characterize the prevalence of physical activity in the population aged ≥16 years integrating sedentarism and physical inactivity. METHOD: A cross-sectional study using data from the Galician Risk Behavior Data System (n=12,928) was conducted. The population was classified into four categories: physically active (active and non-sedentary), active but sedentary (active and sedentary), lightly active (inactive and non-sedentary), and extremely sedentary (inactive and sedentary). Prevalences were calculated for each category and a multinomial logistic regression model was fitted. RESULTS: 58.0% of the population was physically active and the remaining 42.0% presented some degree of sedentarism and/or physical inactivity. Men were more likely to be extremely sedentary. The risk of sedentarism decreased with age, and workers and/or students were prone to a higher risk of extreme sedentarism in comparison to those who reported other status. Extremely sendentary behaviors were also more common in people with higher educational levels, individuals living alone, residents of urban environments, and smokers. CONCLUSIONS: Joint evaluation of sedentarism and physical inactivity provides a more comprehensive and realistic picture of population behaviors related with physical activity. Since sedentarism is the most prevalent behavior, this study recommends that interventions be conducted at work and at academic environments.

[Perception of dating violence among adolescents. Transversal study.] / Percepción de violencia en el noviazgo entre los adolescentes. Estudio transversal.

OBJECTIVE: The violence produced in the context of dating is known as dating violence. Currently, it is a widespread problem in adolescence and there is a great lack of knowledge about the beliefs/attitudes that help perpetuate this phenomenon. This study aimed to assess how adolescents perceive dating violence. Additionally, to estimate the observed frequency of exposure of adolescents to different dating violence items, assessing the differences according to sex and educational level. METHODS: A cross-sectional study was carried out in 2022 among high school students coming from Spain (Galician Region) The data was collected by means of an anonymous online questionnaire. A descriptive analysis of the data obtained was conducted. The observed frequency of adolescents' exposure to different items of dating violence and identification of violence was estimated. Fisher's exact test was used to compare the proportions according to sex and educational level. RESULTS: 410 students were included. 99% of the women perceived that it is not normal to control their partner's clothing compared to 88% of the men; in relation to the control of friendships these percentages were 87.6% and 73.1% and with respect to criticism of the partner 54.7% vs 67.9%, respectively in women and men. 46.8% of the students admitted knowing of cases in which they sent several messages a day to find out what their partner was doing. 21.7% referred to be aware of cases who felt fear of the partner. CONCLUSIONS: The perception of dating violence by women is higher. The largest differences between men and women are in the items of the control domain.

OBJETIVO: La violencia en la pareja que se produce en adolescentes se conoce con el nombre de violencia en el noviazgo. Actualmente, es un problema generalizado en la adolescencia y existe un gran desconocimiento al respecto de las creencias/actitudes que están ayudando a perpetuar este fenómeno. El objetivo de este estudio fue conocer la percepción de los adolescentes sobre esta violencia y estimar la frecuencia observada de exposición a diferentes ítems de violencia en el noviazgo, valorando las diferencias según sexo y nivel educativo. METODOS: Se realizó en 2022 un estudio transversal en cuatro centros educativos públicos de Galicia (España) que impartían Educación Secundaria Obligatoria y Bachillerato. El muestreo de los centros fue de conveniencia. Se invitó a los estudiantes a contestar un cuestionario anónimo. Se estimó la frecuencia observada de exposición del estudiantado a diferentes ítems de violencia en el noviazgo y de identificación de la violencia. Para comparar las proporciones en función del sexo y del nivel educativo se empleó la prueba exacta de Fisher. RESULTADOS: Se incluyeron 410 estudiantes. El 99% de las mujeres percibieron que no es normal controlar la vestimenta de la pareja frente al 88% de los hombres; en relación con el control de las amistades, estos porcentajes fueron del 87,6% y el 73,1%, en mujeres y hombres, respectivamente. Con respecto a las críticas a la pareja, estos porcentajes fueron del 54,7% frente al 67,9%, respectivamente en mujeres y hombres. El 46,8% del estudiantado admitió conocer casos que enviaban varios mensajes al día para saber qué estaba haciendo la pareja. El 21,7% refirió conocer casos que sentían miedo de su pareja. CONCLUSIONES: La percepción de violencia en el noviazgo es mayor por parte de las mujeres. Las mayores diferencias entre hombres y mujeres se observan en los ítems del dominio control.

Face Masks at the Gymnasium: Physiological Responses and Mechanical Performance Are Not Compromised by Wearing Surgical or Filtering Facepiece 2 Masks in Healthy Subjects.

ABSTRACT: Rial-Vázquez, J, Nine, I, Guerrero-Moreno, JM, Rúa-Alonso, M, Fariñas, J, Márquez, G, Giráldez-García, MA, Méndez-Bouza, KY, López-Pillado, H, Coutado-Sánchez, E, Losada-Rodríguez, A, and Iglesias-Soler, E. Face masks at the gym: physiological responses and mechanical performance are not compromised by wearing surgical or filtering facepiece 2 masks in healthy subjects. J Strength Cond Res 37(7): 1404-1410, 2023-This study explored the effects of wearing 2 types of face masks on mechanical performance and physiological responses during high-intensity resistance exercise. Twelve healthy men performed 3 workout protocols in a randomized order: wearing a surgical or filtering facepiece 2 (FFP2) mask or without a mask. Each workout consisted of 3 sets of 10 repetitions of bench press (BP) and parallel squat (SQ) with a 12 repetition maximum load, including 2 minutes of recovery between sets and exercises. Mechanical performance was evaluated through the mean propulsive velocity and the number of repetitions completed during each session. Physiological responses were the oxygen saturation (SpO2), blood lactate concentration, heart rate (HR), and HR variability. Perceived exertion was recorded after each set, and The Beck Anxiety Inventory scale was completed at the end of each workout. The number of repetitions completed and the session mean propulsive velocity {(BP [m·s-1]: surgical: 0.35 ± 0.05; FFP2: 0.36 ± 0.04; nonmask: 0.38 ± 0.06) and (SQ: surgical: 0.43 ± 0.05; FFP2: 0.40 ± 0.07; nonmask: 0.41 ± 0.05)} were similar between conditions (p > 0.05). Heart rate recorded during sessions was similar across conditions: surgical: 119 ± 14, FFP2: 117 ± 13, and nonmask: 118 ± 10 bpm (p = 0.919). Face masks had no effect on SpO2, blood lactate concentration, HR variability, perceived exertion, and anxiety values (p > 0.05). Face masks do not compromise strength performance, physiological parameters, and perceived comfort of young and healthy individuals during a high-intensity resistance training session.

[Short version of the Minnesota Leisure Time Physical Activity Questionnaire for general population: MLTPAQ 9+2]. / Versión reducida del Minnesota Leisure Time Physical Activity Questionnaire para población general: MLTPAQ 9+2.

The aim of this study was to propose a short version of the Minnesota Leisure Time Physical Activity Questionnaire (MLTPAQ) to estimate the prevalence of physical inactivity. MLTPAQ was included in the Galician Risk Behavior Information System survey. Each activity was associated with an intensity code, in multiples of 1 MET, and a weekly energy expenditure of less than 1000kcal was defined as physically inactive. The prevalence of physical inactivity was calculated with the complete and short list (nine activities are performed by at least 10% of the population). The complete and short list classify physical inactivity with an agreement of 98,8%. Misclassified people do one or two more activities, so two open response items were included. This study proposes a short version (9+2 items), suitable for inclusion in a general adult population health survey.

Proteogenomic and V(D)J Analysis of Human Decidual T Cells Highlights Unique Transcriptional Programming and Clonal Distribution.

Immunological tolerance toward the semiallogeneic fetus is one of many maternal adaptations required for a successful pregnancy. T cells are major players of the adaptive immune system and balance tolerance and protection at the maternal-fetal interface; however, their repertoire and subset programming are still poorly understood. Using emerging single-cell RNA sequencing technologies, we simultaneously obtained transcript, limited protein, and receptor repertoire at the single-cell level, from decidual and matched maternal peripheral human T cells. The decidua maintains a tissue-specific distribution of T cell subsets compared with the periphery. We find that decidual T cells maintain a unique transcriptome programming, characterized by restraint of inflammatory pathways by overexpression of negative regulators (DUSP, TNFAIP3, ZFP36) and expression of PD-1, CTLA-4, TIGIT, and LAG3 in some CD8 clusters. Finally, analyzing TCR clonotypes demonstrated decreased diversity in specific decidual T cell populations. Overall, our data demonstrate the power of multiomics analysis in revealing regulation of fetal-maternal immune coexistence.

[Physical activity in the regional health plans in Spain: a review of proposals]. / La actividad física en los planes de salud autonómicos de España. Una revisión de propuestas.

OBJECTIVE: To identify if the regional government health plans in Spain include specific objectives and measures related to physical activity. METHOD: Institutional websites were scanned to identify the most recent health plan of each regional government. The information included in the health plans on objectives and measures and the population groups targeted by these measures was extracted. The search was completed on 24 January 2022. RESULTS: Sixteen health plans were identified of which six are in force in 2022; 15 of these have incorporated specific objectives and measures on physical activity. Most of the actions are focus on general population, children-adolescents and elderly population. The plans of Cantabria, the Comunitat Valenciana and País Vasco cover physical activity more widely, proposing measures for seven of the eight identified population groups. CONCLUSIONS: Most of the health plans include measures related to physical activity and target two or more population groups. The objectives, specific measures and population groups were highly heterogeneous. This study could serve to prompt regional governments to review their health plans, update them and improve them in terms of physical activity. It seems advisable that the different health plans should have a homogeneous framework of proposals related to the promotion of physical activity.

Clinical utility of SARS-CoV-2 subgenomic RT-PCR in a pediatric quaternary care setting.

BACKGROUND: During active transcription, SARS-CoV-2 generates subgenomic regions of viral RNA. While standard SARS-CoV-2 RT-PCR amplifies region(s) of genomic RNA, it cannot distinguish active infection from remnant viral genomic material. However, screening for subgenomic RNA (sgRNA) by RT-PCR may aid in the determination of actively transcribing virus. OBJECTIVES: To evaluate the clinical utility of SARS-CoV-2 sgRNA RT-PCR testing in a pediatric population. STUDY DESIGN: Retrospective analysis was performed on inpatients from February-September 2022 positive for SARS-CoV-2 by RT-PCR with a concomitant order for sgRNA RT-PCR. Chart abstractions were conducted to determine clinical outcomes, management, and infection prevention and control (IPC) practices. RESULTS: Of 95 SARS-CoV-2 positive samples from 75 unique patients, 27 (28.4%) were positive by sgRNA RT-PCR. A negative sgRNA RT-PCR test allowed for de-isolation in 68 (71.6%) patient episodes. Regardless of age or sex, a positive sgRNA RT-PCR result significantly correlated with disease severity (P = 0.007), generalized COVID-19 symptoms (P = 0.012), hospitalization for COVID-19 (P = 0.019), and immune status (P = 0.024). Moreover, sgRNA RT-PCR results prompted changes in management in 28 patients (37.3%); specifically, therapeutic escalation in 13/27 (48.1%) positives and de-escalation in 15/68 (22.1%) negatives. CONCLUSIONS: Taken together, these findings underscore the clinical utility of sgRNA RT-PCR testing in a pediatric population as we report significant associations between sgRNA RT-PCR results and clinical parameters related to COVID-19. These findings align with the proposed use of sgRNA RT-PCR testing to guide patient management and IPC practices in the hospital setting.

Actividad física en el embarazo y puerperio: prevalencia y recomendaciones de los profesionales sanitarios / Physical activity during pregnancy and postpartum: prevalence and healthcare professionals recommendations

Objetivo: Valorar los cambios en la realización de actividad física (AF) en el embarazo y después del parto y explorarlo en función de la edad y el nivel de estudios. Analizar si los profesionales sanitarios dieron recomendaciones sobre la AF. Diseño: Estudio observacional. Sitio: La información procede del Sistema de Información sobre Conductas de Riesgo de Galicia. Participantes: La población objetivo fueron mujeres gallegas (18-49 años) que dieron a luz entre septiembre-2015 y agosto-2016. Medidas principales: Se estimó la prevalencia de realización de caminatas, ejercicio físico (EF) y recomendaciones de realización de la AF en tres momentos (pre-embarazo, embarazo y tras parto). Resultados: Las caminatas aumentaron 34,0% durante el embarazo y el ejercicio disminuyó 21,0%. Tras el parto las caminatas disminuyeron 37,0% y el ejercicio 32,0%, en comparación con el embarazo. Las mujeres de menor edad y con menor nivel educativo son las que realizan menos AF; 72,6 y 22,1% de las mujeres declaró que un profesional sanitario les recomendó AF durante el embarazo y tras el parto, respectivamente. Conclusión: La AF realizada durante el embarazo es fundamentalmente la caminata, y preocupa su abandono tras el parto. Los profesionales sanitarios recomiendan AF principalmente durante el embarazo, pero poco tras el parto. Para mejorar estas prevalencias sería conveniente el refuerzo de la acción sanitaria.(AU)

Objective: To assess changes in physical activity (PA) during pregnancy and after giving birth and to explore this according to age and educational level. To analyze whether the health professionals gave recommendations on PA. Design: Observational study. Site: Information is derived from the Galician Risk Behavior Information System. Participants: The target population was Galician women (aged 18-49 years) who delivered between september-2015 and august-2016. Main measurements: The prevalence of walking, physical exercise and PA recommendations were estimated for three moments (pre-pregnancy, pregnancy and after delivery). Results: Walking during pregnancy increased by 34,0% and the performance of physical exercise decreased by 21,0%. After delivery, walking decreased by 37,0% and physical exercise decreased by 32,0% compared to pregnancy. Women of younger age and lower educational level were those who performed less PA. 72,6% and 22,1% of women declared that a healthcare professional recommended PA during pregnancy and after delivery, respectively. Conclusion: The PA performed by women during pregnancy is mainly walking, and there is a concern about the abandonment of PA practice after delivery. Healthcare professionals recommend PA mainly during pregnancy, but little is recommended after delivery. It may be desirable for the improvement of this prevalence to reinforce health action.(AU)

Cross education is modulated by set configuration in knee extension exercise.

OBJECTIVES: The main aim of this study was to determine the effects of set configuration during five weeks of unilateral knee extension resistance training on untrained knee extensors performance. METHODS: Thirty-five subjects were randomly assigned to traditional training (TTG; n=14), rest-redistribution (RRG; n=10) and control group (CON; n=11). TTG and RRG groups trained the dominant knee extensors twice a week with the 10-repetition maximum (RM) load. TTG performed four sets of eight repetitions with three min-rest between sets and RRG 32 repetitions with 17.4 seconds of rest between each one. Before and after interventions, anthropometry, muscle thickness (MT), pennation angle (PA), 1RM, number of repetitions with 10RM pretest load (N10RM), maximum propulsive power (MPP) and maximum voluntary isometric contraction (MVIC) were measured. RESULTS: 1RM of the untrained leg increased only in the TTG group (p<0.001, 10.3% compared with Pre-test). 1RM, MPP and N10RM increased in the trained leg in both TTG (p<0.001) and RRG (p<0.001). No changes occurred in MT or PA. CONCLUSIONS: These results suggest that, when it is not possible to perform bilateral exercises (e.g., leg injury), traditional set configurations should be recommended to improve maximal voluntary force in the untrained leg.

[Physical activity during pregnancy and postpartum: prevalence and healthcare professionals recommendations]. / Actividad física en el embarazo y puerperio: prevalencia y recomendaciones de los profesionales sanitarios.

OBJECTIVE: To assess changes in physical activity (PA) during pregnancy and after giving birth and to explore this according to age and educational level. To analyze whether the health professionals gave recommendations on PA. DESIGN: Observational study. SITE: Information is derived from the Galician Risk Behavior Information System. PARTICIPANTS: The target population was Galician women (aged 18-49 years) who delivered between september-2015 and august-2016. MAIN MEASUREMENTS: The prevalence of walking, physical exercise and PA recommendations were estimated for three moments (pre-pregnancy, pregnancy and after delivery). RESULTS: Walking during pregnancy increased by 34,0% and the performance of physical exercise decreased by 21,0%. After delivery, walking decreased by 37,0% and physical exercise decreased by 32,0% compared to pregnancy. Women of younger age and lower educational level were those who performed less PA. 72,6% and 22,1% of women declared that a healthcare professional recommended PA during pregnancy and after delivery, respectively. CONCLUSION: The PA performed by women during pregnancy is mainly walking, and there is a concern about the abandonment of PA practice after delivery. Healthcare professionals recommend PA mainly during pregnancy, but little is recommended after delivery. It may be desirable for the improvement of this prevalence to reinforce health action.

Heart Rate Responses and Cardiovascular Adaptations to Resistance Training Programs Differing in Set Configuration: A Randomized Controlled Trial.

Purpose: This study explored the changes in blood pressure and cardiac autonomic modulation after training programs differin in set configuration. Methods: Thirty-nine individuals were randomly assigned to a traditional, rest-redistribution, or control group. Throughout five weeks, the traditional and rest-redistribution groups performed 10 sessions of four exercises with the same load, number of repetitions, and total rest time, but with different inter-set rest duration and frequency (traditional group: 4 sets of 8 repetitions, 10 repetition maximum load, 5 min rest between sets and exercises; rest-redistribution group: 16 sets of 2 repetitions, 1 min rest between sets, 5 min rest between exercises). Heart rate and heart rate recovery were recorded during each training session, and heart rate variability, baroreflex sensitivity and effectiveness, blood pressure, and blood pressure variability were evaluated at rest bedore and after the interventions. Results: During the sessions, traditional sets entailed greater peak heart rate compared to rest-redistribution (P = .018) but mean heart rate, minimum heart rate, and heart rate recovery were similar between training programs (P >.05). Baroreflex effectiveness was reduced after the traditional intervention (P = .013). No changes were detected for the rest of the cardiovascular variables obtained at rest after intervention (P > .05). Conclusions: Despite some differences in heart rate response during exercise, neither traditional nor rest-redistribution resistance training protocols produced changes in cardiac autonomic modulation, sympathetic vasomotor tone, and cardiac baroreflex sensitivity of young healthy active individuals. However, traditional sets affected the baroreflex effectiveness.