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J Chemother ; 9(3): 238-40, 1997 Jun.
Article in English | MEDLINE | ID: mdl-9210009

ABSTRACT

Two seriously neutropenic patients (a 23-year-old man with a promyelocytic acute myeloid leukemia [AML-M3] and a 77-year old male with an immature acute myeloid leukemia [AML-M1] diagnosis) with severe infections caused by Stenotrophomonas maltophilia were treated with aztreonam/clavulanic acid (2:1) combination. In the first patient the infection was caused by a multiresistant strain and in the second, by a strain with poor response to trimethoprim-sulfamethoxazole and other antimicrobial agents. After treatment with aztreonam/clavulanic acid both patients evolved favorably.


Subject(s)
Aztreonam/therapeutic use , Clavulanic Acids/therapeutic use , Drug Therapy, Combination/therapeutic use , Gram-Negative Bacterial Infections/drug therapy , Neutropenia/etiology , Xanthomonas/drug effects , Adult , Aged , Clavulanic Acid , Drug Resistance, Multiple , Gram-Negative Bacterial Infections/complications , Humans , Leukemia, Myeloid/complications , Male
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