ABSTRACT
In fixed Wistar line rats, neuronal activity of the ventromedial hypothalamus was studied in conditions of acute emotional stress elicited by electric stimulation of the ventromedial hypothalamus stochastically alternating with electrocutaneous stimuli. Distinctions were revealed in neuronal activity of the animals with different stress resistance. The pattern of neuronal impulse activity proved to be the most informative one.
Subject(s)
Hypothalamus, Middle/physiopathology , Stress, Psychological/physiopathology , Action Potentials , Acute Disease , Animals , Brain Mapping , Disease Susceptibility , Electric Stimulation , Humans , Male , Rats , Rats, Inbred StrainsABSTRACT
Irregularity of the rhythm of breathing, the breathing rate, blood pressure and heart rate were studied in rats under acute emotional stress induced by non-periodic stimulation of the skin and ventromedial hypothalamus. The irregularity of the rhythm of breathing was substantially increased during stimulation of the hypothalamus up to short-term respiratory arrests in animals predisposed to emotional stress. Disturbances of the rhythm of breathing may be one of objective prognostic criteria of the animals' survival or lethality under emotional stress.