1.
Bull Exp Biol Med
; 166(2): 293-296, 2018 Dec.
Article
in English
| MEDLINE
| ID: mdl-30488198
ABSTRACT
We propose an in vitro model of chronic oxidative stress based on the use of glucose oxidase. Oxidative stress modeling leads to a significant increase in the number of dead cells in culture. It was shown that the glial cell-derived neurotrophic factor exhibits a pronounced anti-oxidant effect. Preventive application of 1 ng/ml glial cell-derived neurotrophic factor significantly reduced the percentage of dead cells in culture.