ABSTRACT
Sporotrichosis is a cosmopolitan, chronic granulomatous mycosis, acquired by traumatic inoculation and caused by Sporothrix schenckii complex. Several methods of diagnostic are available, from KOH to molecular biology. In this review, we describe from the simplest (clinical diagnosis) to the most advanced diagnostic techniques (molecular biology).
ABSTRACT
Myopericytoma is a soft-tissue tumor of perivascular cells (pericytes). It is slow-growing, usually asymptomatic, and generally benign, although a malignant variant has been described. The etiology is unknown, but it has been associated with local trauma. The most common location is on the distal extremities. Histologically, it is characterized by a well-circumscribed, non-encapsulated proliferation of spindle shaped cells similar to myofibroblasts with oval nuclei and eosinophilic cytoplasm, arranged in perivascular concentric rings. There are few mitoses and no necrosis is reported. The immunohistochemical analysis is positive for smooth muscle actin and negative or weakly positive for desmin. A low Ki-67 proliferation index is typical. Treatment is surgical excision with free margins. Recurrences after adequate excision are uncommon. We describe a 48-year-old woman with a myopericytoma in an unusual location (next to the inner corner of her left eye) who was treated with surgical excision; there has been no recurrence after 5 years of follow up.
Subject(s)
Facial Neoplasms/diagnosis , Myofibroma/diagnosis , Neoplasm Recurrence, Local/surgery , Skin Neoplasms/diagnosis , Eye , Facial Neoplasms/pathology , Facial Neoplasms/surgery , Female , Humans , Middle Aged , Myofibroma/pathology , Myofibroma/surgery , Pericytes/pathology , Skin Neoplasms/pathology , Skin Neoplasms/surgeryABSTRACT
INTRODUCTION: Renal cell carcinoma (RCC) accounts for 2-3% of adult solid malignancies. About 25-30% develop metastasis at the time of diagnosis and 60% corresponds to clear cell type. CASE PRESENTATION: A 66-year-old man, with a personal history of left radical nephrectomy, presents with an asymptomatic skin tumor he noticed one month earlier. Histopathologic study reported metastatic cutaneous infiltration of clear cell carcinoma, suggestive of a primary renal carcinoma. DISCUSSION: Cutaneous metastasis of RCC represents 6.0-6.8% of all cutaneous metastases. These patients have poor prognosis and, therefore, their treatment is palliative. It is essential to perform a complete periodic dermatologic examination for proper restaging and treatment.
Subject(s)
Carcinoma, Renal Cell/secondary , Kidney Neoplasms/pathology , Skin Neoplasms/secondary , Aged , Humans , MaleSubject(s)
Foot Dermatoses/diagnosis , Foot Dermatoses/therapy , Skin Care , Foot Dermatoses/etiology , Humans , Odorants , RecurrenceABSTRACT
AIM: To determine the prevalence of oral lesions (OL) in patients with psoriasis, and compare these findings with the ones found in patients without this condition. MATERIALS AND METHODS: In the present observational and comparative study, we evaluated 207 patients, with and without psoriasis, attending the dermatological consulting service of a concentration hospital in Mexico City. The possible association between OL and psoriasis was analyzed through a logistic regression model; the Odds Ratio (OR) and its Confidence Interval (CI) was calculated to be 95%. RESULTS: Two hundred and seven cases were examined (80 with psoriasis and 127 without psoriasis). Of these, 75 (36.2%) were men and 132 (63.7%) women. Oral lesions were found in 54 (67.5%) psoriatic patients and in 63 (49.6%) of the comparative group (p <0.012). Fissured tongue (FT) was present in 47.5 % of the patients with psoriasis and in 20.4 % of the group without psoriasis, (OR=3.46, 95% CI [1.14, 10.5], p=0.001). Geographic tongue (GT) was present in 12.5 % of the group with psoriasis and 4.7 % in the group without this disease (OR=3.54 95 % CI [1.97, 6.79], p=0.028). Likewise, six patients (7.5 %) with psoriasis and 3 (2.36 %) from the comparative group presented simultaneously GT and FT (p = 0.0776). The most frequent type of psoriasis was the vulgar psoriasis (90 %), in which a higher prevalence of FT (p <0.05) was present. There were no differences between both groups (p>0.05) regarding the use of tobacco. Alcohol consumption was greater (55.0%) among patients with psoriasis than among those without psoriasis (26.7%) (p<0.05), but when the association with GT and FT was analyzed, no significant differences were found among consumers and not consumers of tobacco and alcohol (p> 0.05). CONCLUSIONS: The high prevalence of GT and FT in patients with psoriasis suggests that these lesions should be taken into account in new studies as possible predictors or markers of the severity of this dermatosis, in order to confirm the association of these entities.
Subject(s)
Mouth Diseases/epidemiology , Mouth Diseases/etiology , Psoriasis/complications , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Prevalence , Young AdultABSTRACT
Congenital generalized terminal hypertrichosis is a rare disease, especially when associated with gingival hyperplasia. Congenital hypertrichosis can be a clinical feature of several syndromes, so these patients must be studied by a multidisciplinary team that should include a dermatologist, geneticist, psychologist, odontologist, and an endocrinologist. We report a 7-year-old girl with congenital generalized hypertrichosis and gingival hyperplasia, and analyze the clinical approach, differential diagnosis, and treatment.
Subject(s)
Gingival Hyperplasia/congenital , Hypertrichosis/congenital , Child , Female , Gingival Hyperplasia/complications , Gingival Hyperplasia/surgery , Humans , Hypertrichosis/complications , Hypertrichosis/pathologyABSTRACT
Se comunica un caso de carcinoma de la glándula de Meibomio en una mujer de 82 años de edad. Este tumor es poco frecuente y puede condundirse clínica e histológicamente con un carcinoma epidermoide.
Subject(s)
Humans , Female , Aged , Carcinoma, Squamous Cell/diagnosis , Carcinoma/diagnosis , Diagnosis, Differential , Meibomian Glands/pathology , Eyelid Neoplasms/diagnosis , Carcinoma/classificationABSTRACT
Se presenta el caso de una paciente del sexo femenino de 75 años de edad, que presentaba en talón derecho un melanoma amelánico, diagnosticado por medio de estudio citológico, se efectuó corroboración histológica. Se describen los hallazgos citológicos.
Subject(s)
Humans , Female , Aged , Cell Biology , Diagnosis , Melanoma/diagnosisABSTRACT
Presentamos el caso de una paciente del sexo femenino de 29 años de edad, que tenía en región preauricular derecha un nevo sebáceo de Jadassohn, sobre el que se desarrolló un carcinoma basocelular, poroma ecrino e hidrocistomas apócrinos. La asociación del nevo sebáceo con el poroma ecrino no había sido descrita previamente.
Subject(s)
Humans , Female , Adult , Carcinoma, Basal Cell/pathology , Nevus/pathology , Sebaceous Gland Neoplasms/pathology , Sweat Gland Neoplasms/pathology , Apocrine Glands/pathology , Eccrine Glands/pathology , Mexico , Neoplasms, Multiple Primary/pathologyABSTRACT
Se reporta el caso de un paciente masculino con queilitis granulomatosa y lengua escrotal, tratado con queilectomía, con resultados favorables
