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1.
Arch Esp Urol ; 54(4): 370-4, 2001 May.
Article in Spanish | MEDLINE | ID: mdl-11455774

ABSTRACT

OBJECTIVE: To report a case of Wilms' tumor in an adult patient. METHODS: The records of an adult patient with renal tumor is reviewed. RESULTS: A 23-year-old male consulted for hematuria. Physical examination and patient assessment by ultrasound and CT showed a solid tumor in the right kidney. The patient was submitted to radical surgery. Pathological analysis demonstrated a biphasic nephroblastoma (Wilms' tumor) with infiltration of renal hilar fat (stage II). After surgery, adjuvant chemotherapy with vincristine-actinomycin D was administered for 60 weeks. CONCLUSIONS: Although rare in adults, Wilms' tumor should be included in the differential diagnosis of all renal tumors. Treatment is usually by surgery and chemotherapy with or without radiotherapy, depending on tumor stage.


Subject(s)
Kidney Neoplasms/pathology , Wilms Tumor/pathology , Adult , Humans , Male
3.
N Engl J Med ; 339(4): 268-9, 1998 Jul 23.
Article in English | MEDLINE | ID: mdl-9687252
4.
An Med Interna ; 15(9): 487-9, 1998 Sep.
Article in Spanish | MEDLINE | ID: mdl-10079542

ABSTRACT

We present an AIDs patient who was admitted to our hospital because of dry cough, pleuritic chest pain, fever and bilateral lung nodules on the chest X-ray. An open lung biopsy was diagnostic for Lymphomatoid Granulomatosis (GL). We review the literature of the clinical manifestations, anatomopathological and pathogenetic features, roentgenographic and laboratory findings, as well as treatment strategies of these patients. The GL has been described in association with AIDS, although in spite of the high prevalence of AIDS in our days, the association between these two entities is not frequent according to the few references in the literature.


Subject(s)
Acquired Immunodeficiency Syndrome/complications , Lymphomatoid Granulomatosis/complications , Adult , Humans , Lymphomatoid Granulomatosis/diagnosis , Lymphomatoid Granulomatosis/therapy , Male
5.
Rev Neurol ; 25 Suppl 3: S269-80, 1997 Sep.
Article in Spanish | MEDLINE | ID: mdl-9273173

ABSTRACT

Cutaneous biopsy is of great use in the diagnosis of neurodegenerative diseases, especially neurometabolic and inborn errors of metabolism. The sweat glands, especially the eccrine ones, and certain cellular elements in the adventitial dermis like the Schwann cells, axons, endothelium and fibroblasts, are altered in inborn errors of metabolism and in certain neurodegenerative diseases. The morphology and placement of these deposits, as for example axonal spheroids, Lafora bodies, homogeneous cytoplasmic bodies and prismatic bodies, permit to diagnosis the disease. Differential diagnosis must be made with simulating storage disorders. The study of skin biopsy must be complete and rigorous and follow a system of work, that includes electron microscopy, enzymatic determination and, occasionally, molecular biology. Valuable information about neurodegenerative diseases as muscular dystrophies, axonal neuropathy, Alzheimer disease and others can be carried out by skin biopsy. It can be foreseen that in the future indications of skin biopsy will be extended to other neurodegenerative diseases.


Subject(s)
Metabolism, Inborn Errors/pathology , Skin/pathology , Axons/pathology , Biopsy , Diagnosis, Differential , Epithelium/ultrastructure , Humans , Metabolism, Inborn Errors/diagnosis , Muscular Dystrophies/pathology , Schwann Cells/pathology , Sweat Glands/pathology
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