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Zh Nevrol Psikhiatr Im S S Korsakova ; 124(4. Vyp. 2): 41-48, 2024.
Article in Russian | MEDLINE | ID: mdl-38696150

ABSTRACT

Arterial hypertension (AH) is a leading risk factor for cardiovascular diseases including cerebrovascular complications. Strokes and/or vascular cognitive impairment (VCI) are considered as a clinical sign of brain damage as a target organ in hypertension. To identify and assess the severity of VCI, patients with hypertension should undergo a neuropsychological assessment. Neuroimaging confirm the vascular origin of cognitive impairment. Patient management should include antihypertensive therapy along with neuroprotection. Among different neuroprotective therapy, ethylmethylhydroxypyridine succinate (mexidol) is one of medication with serious evidence of clinical efficacy.


Subject(s)
Cognitive Dysfunction , Hypertension , Picolines , Humans , Hypertension/complications , Hypertension/drug therapy , Cognitive Dysfunction/etiology , Cognitive Dysfunction/diagnosis , Picolines/therapeutic use , Antihypertensive Agents/therapeutic use , Neuroprotective Agents/therapeutic use , Neuropsychological Tests
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