ABSTRACT
There has been a significant increase in diabetes morbidity in the past years. Prolonged asymptomatic progression of disease presents a problem and leads to late diagnosis and development of complications. Present study shows efficiency of screening measures to determine actual spread of carbohydrate metabolism disorders among residents of Odessa, frequency of type 2 diabetes mellitus risk factors determination and prevention of complications.
Subject(s)
Diabetes Mellitus, Type 2/epidemiology , Hypertension/epidemiology , Mass Screening/methods , Obesity/epidemiology , Adult , Aged , Aged, 80 and over , Blood Glucose/metabolism , Carbohydrate Metabolism , Diabetes Mellitus, Type 2/blood , Diabetes Mellitus, Type 2/complications , Diabetes Mellitus, Type 2/diagnosis , Disease Progression , Female , Humans , Hypertension/blood , Hypertension/complications , Hypertension/diagnosis , Incidence , Male , Middle Aged , Obesity/blood , Obesity/complications , Obesity/diagnosis , Physical Examination , Risk Factors , Ukraine/epidemiologyABSTRACT
Endotoxinemia was caused in rats by the lipopolysaccharide (LPS) oral application at the doses 40 mkg/kg and 200 mkg/kg. The increase of the content of triglycerides in the blood serum and in the liver was established. Besides, the LPS oral application at the dose 200 ΜΚΓ/ΚΓ the increase of the content of cholesterol in the liver was established.
Subject(s)
Cholesterol/blood , Lipid Metabolism/drug effects , Lipopolysaccharides/pharmacology , Liver/drug effects , Triglycerides/blood , Administration, Oral , Animals , Dose-Response Relationship, Drug , Liver/metabolism , Mouth Mucosa/drug effects , Mouth Mucosa/metabolism , RatsSubject(s)
Opisthorchis/physiology , Preservation, Biological/methods , Animals , Petrolatum , Plant OilsSubject(s)
Opisthorchiasis/etiology , Zoonoses/etiology , Animals , Disease Reservoirs , Fishes/parasitology , Humans , Kazakhstan , Water SupplyABSTRACT
The experiments were carried out to study hemopoietic and stromal cells of bone marrow subendosteal regions during T-cell lymphomagenesis in AKR mice, using transmission electron microscopy and electron microscopic immunocytochemistry methods. It is shown that the subendosteal region of mice with lympholeukosis is replaced by lymphocytes at different stages of differentiation with certain ultrastructural peculiarities. The association of alkaline-phosphatase positive reticulum cells with granulocytes is destroyed. The alkaline phosphatase activity in reticulum cells of the subendosteal region of mice with spontaneous lympholeukosis is very low or absent. The results obtained may be useful for understanding the AKR lymphomagenesis.
