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1.
Cir. Esp. (Ed. impr.) ; 95(2): 97-101, feb. 2017. graf, tab
Article in Spanish | IBECS | ID: ibc-162229

ABSTRACT

INTRODUCCIÓN: El objetivo de este estudio es presentar nuestra serie de pacientes con carcinoma pulmonar y metástasis única suprarrenal sincrónica tratados de manera secuencial inversa: primero adrenalectomía y después resección pulmonar. MÉTODOS: Del total de 108 adrenalectomías laparoscópicas transperitoneales realizadas se analiza de manera retrospectiva una serie consecutiva de 10 pacientes diagnosticados de tumor primario de pulmón con metástasis suprarrenal sincrónica tratados de manera secuencial inversa. A todos se les realizó mediastinoscopia de estadificación; aquellos con metástasis ganglionares recibieron inducción. Las variables analizadas fueron: morbilidad tras adrenalectomía y tras resección pulmonar, estancia hospitalaria, tiempo entre ambas intervenciones, intervalo libre de enfermedad y supervivencia global. La supervivencia se analizó según el método de Kaplan-Meier. RESULTADOS: Edad media: 56,8 años (rango: 41-73). Del total, 8 casos se intervinieron por laparoscopia. Tamaño medio de la metástasis: 5,9cm (rango: 3-10). Tiempo medio entre ambas intervenciones: 28 días (rango: 12-35). No hubo complicaciones tras la adrenalectomía. Estancia media: 4,3 días (rango: 3-5). La supervivencia libre de enfermedad a los 2años fue del 50% y la supervivencia global a los 5 años fue del 30%, con una supervivencia global mediana de 41,5 meses (rango: 0-98). CONCLUSIONES: La adrenalectomía para metástasis de carcinoma pulmonar tiene baja morbilidad, no retrasa la resección del tumor primario y permite realizar la resección pulmonar una vez asegurada la resección completa de la metástasis. Por tanto, a falta de ensayos clínicos, un comité multidisciplinar debe considerar de forma individualizada esta opción terapéutica para todos aquellos pacientes en quienes la estadificación clínica de su carcinoma indique que tanto el tumor primario como la metástasis pueden extirparse de forma completa


INTRODUCTION: The aim of this study is to present our patients with lung cancer and synchronous adrenal metastases treated with a reversal approach: starting with adrenalectomy and doing the lung resection second. METHODS: A total of 108 laparoscopic adrenalectomies were performed, and we analyze a consecutive serie of 10 patients with isolated adrenal synchronous metastases from the lung, surgically treated in a sequential way. All patients underwent staging mediastinoscopy, and patients with positive lymph nodes were primary treated with chemotherapy. We analyze: postoperative morbidity, length of stay, time between the 2surgeries, suvival free progression and global survival. Survival analysis was performed by the Kaplan-Meier method. RESULTS: Mean age: 56.8 (41-73) years old. Of the total, 8 patients were surgically performed by laparoscopy. Metastases average size: 5.9 (3-10) cm. Days between the 2surgeries were 28 (12-35) days. No morbidity after adrenalectomy. Length of stay was 4.3 (3-5) days. Disease-free survival at 2 years was 60%, the 5-year overall survival was 30%, with a median survival of 41.5 (0-98) months. CONCLUSIONS: Adrenalectomy involves no significant morbidity and can be performed safely without delaying lung surgery, and allows us to operate the primary lung tumor successfully as long as we ensure complete resection of the adrenal gland. A multidisciplinary oncology committee must individualize all cases and consider this therapeutic approach in all patients with resectable primary tumor and resectable adrenal metastases


Subject(s)
Humans , Adrenal Gland Neoplasms/surgery , Lung Neoplasms/surgery , Adrenalectomy/methods , Neoplasm Metastasis/therapy , Adrenal Gland Neoplasms/secondary , Neoplasms, Multiple Primary/surgery , Carcinoma, Non-Small-Cell Lung/surgery , Epidemiology, Descriptive
4.
Rev Esp Enferm Dig ; 106(6): 418-24, 2014 Jun.
Article in English | MEDLINE | ID: mdl-25361454

ABSTRACT

Phlegmonous gastritis is a rare bacterial infection of the gastric wall, which progress rapidly. It is characterized by a purulent inflammation that can affect the entire gastrointestinal tract and presents a high mortality rate. We are reporting a case of phlegmonous gastritis in an HIV-seropositive man successfully treated with antibiotics. Moreover, a review of the English andSpanish literature is carried out, from 1980 to the present time.The most frequently involved microorganism is Streptococcus spp. (57 %), but the polimicrobial infection is also frequent (17 %). The most important symptom is the intensive epigastric pain associated with vomits and most cases were diagnosed by CT and/or fibrogastroscopy. There are many existing risk factors described.The main one is the immunesuppression, although in 40 % of the cases no risk factors were identified. The global mortality is 27 % without identifying significant differences between antibiotics and surgical treatment, for that reason it is recommended to initiate antibiotic treatment right from the beginning and postponing surgery for the refractory cases and complications.


Subject(s)
Abdomen, Acute/etiology , Gastritis/diagnosis , Adult , Anti-Bacterial Agents/therapeutic use , Gastritis/complications , Gastritis/drug therapy , Humans , Male
6.
Rev. esp. enferm. dig ; 106(6): 418-424, jun. 2014. tab, ilus
Article in Spanish | IBECS | ID: ibc-127435

ABSTRACT

La gastritis flemonosa es una infección bacteriana poco frecuente y rápidamente progresiva de la pared gástrica. Se caracteriza por una inflamación purulenta que puede afectar a todo el tracto gastrointestinal y que presenta un índice elevado de mortalidad. En este trabajo se comunica un caso de gastritis flemonosa en un paciente seropositivo para la infección por VIH tratado exitosamente con antibioticoterapia. Además, se realiza una revisión de los casos publicados en la bibliografía médica, en inglés y español desde 1980 hasta la actualidad. El microorganismo más frecuentemente implicado es Streptococcus spp. (57 %), pero también destaca la infección polimicrobiana (17 %). El síntoma más común es el dolor epigástrico intenso asociado a vómitos y la mayoría de casos fueron diagnosticados mediante TC y/o endoscopia. Existen numerosos factores de riesgo descritos, el principal es la inmunosupresión, aunque en el 40 % de los casos no se identificó ningún factor de riesgo. La mortalidad global es del 27 %, sin identificar diferencias significativas entre el tratamiento antibiótico y quirúrgico, por lo que se recomienda instaurar el tratamiento antibiótico de manera precoz y reservar la cirugía para los casos refractarios y las complicaciones (AU)


Phlegmonous gastritis is a rare bacterial infection of the gastric wall, which progress rapidly. It is characterized by a purulent inflammation that can affect the entire gastrointestinal tract and presents a high mortality rate. We are reporting a case of phlegmonous gastritis in an HIV-seropositive man successfully treated with antibiotics. Moreover, a review of the English and Spanish literature is carried out, from 1980 to the present time. The most frequently involved microorganism is Streptococcus spp. (57 %), but the polimicrobial infection is also frequent (17 %). The most important symptom is the intensive epigastric pain associated with vomits and most cases were diagnosed by CT and/ or fibrogastroscopy. There are many existing risk factors described. The main one is the immunesuppression, although in 40 % of the cases no risk factors were identified. The global mortality is 27 % without identifying significant differences between antibiotics and surgical treatment, for that reason it is recommended to initiate antibiotic treatment right from the beginning and postponing surgery for the refractory cases and complications (AU)


Subject(s)
Humans , Male , Middle Aged , Gastritis/complications , Gastritis/diagnosis , Abdomen, Acute/complications , Abdomen, Acute/diagnosis , Pneumococcal Infections/complications , Streptococcus agalactiae/isolation & purification , Gastric Mucosa/microbiology , Gastric Mucosa/pathology , Gastric Mucosa , Gastritis/therapy
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