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Mini Rev Med Chem
; 7(2): 159-70, 2007 Feb.
Article
in English
| MEDLINE
| ID: mdl-17305590
ABSTRACT
Cholera Toxin (CT) recognizes the cell membrane through specific interactions with ganglioside GM1. Recent structural elucidation of the CT/GM1 complex has allowed the rational design of artificial receptors for the toxin, which could function as anti-cholera drugs. The efforts towards the rational design of Cholera Toxin inhibitors will be presented.