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1.
Ann Vasc Surg ; 24(7): 946-9, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20831995

ABSTRACT

BACKGROUND: It has been well established that inferior vena cava (IVC) filter placement at the time of open gastric bypass (OGB) surgery in patients with a body mass index of more than 55 kg/m(2) reduces both the pulmonary embolism rate and the perioperative mortality. However, little is known about the long-term effects of IVC filter placement in this particular group of patients. METHODS: Over an 8-year period, a total of 571 morbid obese patients underwent OGB procedures, and 58 (10%) of them required placement of an IVC filter before their procedure. All IVC filters were placed percutaneously through a femoral vein approach using a portable OEC fluoroscope. Types of IVC filters used in our study included the TrapEase (n = 35), Simon-Nitinol (n = 9), Greenfield (n = 2), and Bard Recovery (n = 12). RESULTS: Of the 58 patients who required an IVC placement, 56 remained free of any thromboembolic phenomena over the 8-year period (range, 1-8 years). The remaining two patients developed deep venous thrombosis. One patient was successfully treated with intravenous heparin and a 6-month course of Coumadin. She had complete resolution of her deep venous thrombosis and was incidentally noted to have a prothrombin 20210 gene mutation. The other patient, who had multiple gastric bypass complications, could not be successfully treated with intravenous heparin and thus progressed on to complete IVC thrombosis. She developed phlegmasia cerulea dolens and required bilateral above-the-knee amputations. She subsequently died 3 months after her procedures. CONCLUSION: It appears that IVC filter placement at the time of OGB surgery is a relatively benign intervention with a maximal benefit. A note of caution should be exerted for those obese patients who have a hypercoagulable disorder and for those who have complications related to the gastric bypass. An aggressive posture, which may consist of immediate anticoagulation after their procedures (only when it is deemed safe), should be advocated in this small sub-group of morbid obese patients.


Subject(s)
Gastric Bypass , Obesity, Morbid/surgery , Pulmonary Embolism/prevention & control , Vena Cava Filters , Venous Thrombosis/prevention & control , Adult , Anticoagulants/therapeutic use , Body Mass Index , Female , Gastric Bypass/adverse effects , Humans , Male , Obesity, Morbid/blood , Patient Selection , Prosthesis Design , Pulmonary Embolism/diagnosis , Pulmonary Embolism/etiology , Radiography, Abdominal , Risk Assessment , Risk Factors , Severity of Illness Index , Thrombophilia/complications , Time Factors , Treatment Outcome , Ultrasonography, Doppler, Duplex , United States , Venous Thrombosis/diagnosis , Venous Thrombosis/etiology
2.
Ann Vasc Surg ; 21(5): 556-9, 2007 Sep.
Article in English | MEDLINE | ID: mdl-17823038

ABSTRACT

Obesity independently increases the risk of pulmonary embolism (PE). We compare a superobese population (body mass index [BMI] > 55 kg/m(2)) undergoing open gastric bypasses (OGBs) with a similarly matched group of laparoscopic gastric bypasses (LGB) to see if the incidence of PE differs. We included all patients undergoing OGB (n = 193, average BMI = 51 kg/m(2)) at our institution by a single surgeon between July 1999 and April 2001. Thirty-one patients were superobese (BMI > 55 kg/m(2)). LGB was started at our institution in April 2001. Since that time 213 patients (average BMI = 52 kg/m(2)) have undergone the procedure. One hundred and nine patients were superobese. Pre- and postoperative prophylaxis included sequential compression stockings and subcutaneous heparin. Postoperatively, patients who developed signs of hypoxia, tachypnea, or tachycardia underwent a chest X-ray and spiral computed tomography. In addition, all patients who expired in the 30-day postoperative period underwent postmortem examination. Data were analyzed using the chi-squared test. In the OGB group, four patients (2.1%) developed PE. All occurred in superobese patients with a BMI > 55 kg/m(2). Three were fatal PEs and one was nonfatal. None of these patients had a prior history of deep vein thrombosis, PE, venous stasis disease, or pulmonary hypertension. In the LGB group, one patient (0.9%) had a nonfatal PE. This patient had a history of deep vein thrombosis. The incidence of PE was statistically higher in the superobese OGB group (P < 0.01). Despite the theoretical hindrance to venous return and vena caval compression observed with pneumoperitoneum, fewer PEs occurred in the laparoscopic group. Our data, however, suggest that patients with a BMI > 55 kg/m(2) might be at an increased risk for PE independent of operative approach.


Subject(s)
Gastric Bypass/methods , Laparoscopy/methods , Pulmonary Embolism/epidemiology , Anastomosis, Roux-en-Y , Anticoagulants/administration & dosage , Anticoagulants/therapeutic use , Body Mass Index , Case-Control Studies , Femoral Vein/pathology , Heparin/administration & dosage , Heparin/therapeutic use , Humans , Incidence , Injections, Subcutaneous , New York City/epidemiology , Obesity, Morbid/surgery , Radiography, Thoracic , Retrospective Studies , Stockings, Compression , Survival Rate , Tomography, Spiral Computed , Vena Cava Filters , Venous Thrombosis/epidemiology
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