ABSTRACT
The author presents his whole-life experience with biological treatment of mental disorders. He qualified 50 years ago in 1933 and has been psychiatrist for 50 years. During his practice extending over half a century he tested personally and clinical work all biological therapeutic procedures in psychiatry, starting with treatment by pharmacogenic sleep, all types of shock therapy, psychosurgery, modern psychiatric pharmacotherapy as well as possibilities of contemporary prevention of psychiatric diseases by thymoprophylaxis . In this chapter the author presents a chronological review of different types and forms of biological therapy in psychiatry and his own views on the therapeutic effectiveness on different methods of biologically oriented psychiatric therapy.
Subject(s)
Mental Disorders/therapy , Psychotherapy/history , Convulsive Therapy/history , Electronarcosis/history , Europe , History, 20th Century , Humans , Hyperthermia, Induced/history , Mental Disorders/history , Narcotherapy/history , Psychosurgery/history , Psychotherapy/methods , United StatesABSTRACT
Dipropylacetamide (DEPAMIDE) was administered to 60 patients with bipolar manic-depressive psychoses. The dosage was 900 mg per day, administered orally. In 5 (8%) of the patients gastrointestinal disorders were observed. Administration of lithium carbonate results in undesirable side-effects in 50% of the cases. Our clinical experience shows dipropylacetamide to have a considerably slighter toxic effect on the human organism than lithium carbonate. We regard Dipropylacetamide (DEPAMIDE) as a valuable and significant addition in the prophylaxis of affective disorders, notably bipolar manic-depressive psychoses.
