ABSTRACT
We report a rare case of phaeohyphomycotic cyst in an immunocompetent patient caused by Exophiala oligosperma. This fungus is earlier known to cause infections in the immunocompromised. Identification of black fungi at species level is more challenging by conventional methods, and hence final identification of the fungi was based on sequencing of rDNA. The patient was managed with surgical excision. To the best of our knowledge, this is the first case report of E. oligosperma human infection from India.
Subject(s)
Cysts/etiology , Cysts/pathology , Exophiala/isolation & purification , Phaeohyphomycosis/diagnosis , Phaeohyphomycosis/pathology , Adult , Cysts/microbiology , Cysts/surgery , DNA, Bacterial/chemistry , DNA, Bacterial/genetics , DNA, Ribosomal/chemistry , DNA, Ribosomal/genetics , Debridement , Exophiala/classification , Exophiala/genetics , Humans , India , Male , Microscopy , Molecular Sequence Data , Phaeohyphomycosis/microbiology , Phaeohyphomycosis/surgery , Sequence Analysis, DNAABSTRACT
We herewith present a rare and interesting case of gastric signet ring cell lymphoma (SRCL) in a 40-year-old retroviral positive lady. SRCL is a rare morphological variant of nodal lymphomas.Biopsy from the suspected lesion in the stomach showed diffuse sheets of cells with a large central vacuole displacing the nucleus to the periphery of the cell, imparting signet ring cell morphology. Negative reaction to PAS (Periodic acid Schiff) stain and subsequent strong positivity for the immunohistochemical markers such as CD45 (Leucocyte commonantigen) and CD20, a B-cell marker helped us to arrive at a diagnosis of signet ring B- cell lymphoma.
