1.
Antimicrob Agents Chemother
; 54(4): 1623-6, 2010 Apr.
Article
in English
| MEDLINE
| ID: mdl-20100875
ABSTRACT
We characterized 67 Escherichia coli isolates with reduced susceptibility to cefotaxime or ceftiofur obtained from healthy broilers housed in five Italian farms. The bla(CTX-M-1), bla(CTX-M-32) and bla(SHV-12) beta-lactamase genes were identified on IncI1, IncN, or IncFIB plasmids. Considerable genetic diversity was detected among the extended-spectrum beta-lactamase (ESBL)-producing isolates, and we identified indistinguishable strains in unrelated farms and indistinguishable plasmids in genetically unrelated strains. The detection of highly mobile plasmids suggests a potential animal reservoir for beta-lactamase genes.
Subject(s)
Chickens/microbiology , Escherichia coli Proteins/genetics , Escherichia coli/enzymology , Escherichia coli/genetics , beta-Lactamases/genetics , Amplified Fragment Length Polymorphism Analysis , Animals , Cephalosporin Resistance/genetics , Disease Reservoirs/microbiology , Escherichia coli/drug effects , Escherichia coli/isolation & purification , Escherichia coli Infections/drug therapy , Escherichia coli Infections/microbiology , Escherichia coli Infections/transmission , Genes, Bacterial , Genetic Variation , Humans , Italy , Microbial Sensitivity Tests , Plasmids/genetics
2.
Emerg Infect Dis
; 14(5): 852-4, 2008 May.
Article
in English
| MEDLINE
| ID: mdl-18439383
