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Article in English | MEDLINE | ID: mdl-6425236

ABSTRACT

The effects of tritiated amino-acids, arginine, lysine, histidine and aspartic acid on the growth and development of two-cell mouse embryos, cultured in vitro, were investigated. The LD50 for the dibasic amino acids, measured on the third day of growth, ranged from 30 to 130 nCi/ml. This was compared with the DNA precursor, thymidine, for which the LD50 was 80 nCi/ml.


Subject(s)
Amino Acids , Blastocyst/radiation effects , Tritium , Animals , Arginine , Aspartic Acid , Female , Histidine , Lysine , Mice , Thymidine , Time Factors
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