[Lymphocyte subpopulations and the soluble interleukin-2 receptor in Hashimoto's thyroiditis and subacute thyroiditis]. / Studio delle sottopopolazioni linfocitarie e del recettore solubile dell'interleuchina-2 nella tiroidite di Hashimoto e nella tiroidite subacuta.

There are no univocal experimental data in literature about T cell clone alterations in the peripheral blood during Hashimoto's thyroiditis (TH), autoimmune disease, and during subacute thyroiditis (TSA), an inflammatory thyroid lesion with possibility of "self-perpetuation". The object of our research was to examine the T cell clones, soluble fraction of interleukin 2 receptor and HLA-DR modifications in patients with TH and TSA compared with healthy population. Our results show significant increase of sIL-2r in the TSA compared with normal subjects and with patients TH, where on the contrary, a constant increase of HLA-DR was observed.

Diffuse idiopathic skeletal hyperostosis and situs viscerum inversus.

We describe a 74-year-old woman with diffuse idiopathic skeletal hyperostosis (DISH) and situs viscerum inversus. The radiographic alterations typical of DISH were present only on the left side of her thoracic spine. The role of the thoracic aorta in preventing DISH adjacent to its side and some pathogenetic aspects of this skeletal disorder are discussed.