1.
Bull Exp Biol Med
; 152(4): 475-9, 2012 Feb.
Article
in English, Russian
| MEDLINE
| ID: mdl-22803114
ABSTRACT
Oxidized titanium is a biologically inert material, but bioinertness reduces biomechanical characteristics of titanium implants. Modification of the structure of oxide surface layer of BT 5-1 titanium by increasing its thickness (by 1.7 times) and pore diameter (by 1.4 times) and by adding phosphorus, aluminum, and zinc oxides to its composition leads to radical modification of its biological characteristics. These implants acquire osteoinductive properties in in vivo systems not found in pure or oxidized BT 1-00 titanium and fairly well maintain in vitro growth of mesenchymal cells.
Subject(s)
Bone Marrow Cells/drug effects , Coated Materials, Biocompatible/pharmacology , Osseointegration/physiology , Titanium/pharmacology , Aluminum Oxide/chemistry , Animals , Bone Marrow Cells/cytology , Cell Count , Cell Survival/drug effects , Cells, Cultured , Coated Materials, Biocompatible/chemical synthesis , Dental Implants , Dermatologic Surgical Procedures , Materials Testing , Mice , Microscopy, Electron, Scanning , Phosphorus Compounds/chemistry , Porosity , Skin/drug effects , Skin/ultrastructure , Subcutaneous Tissue/drug effects , Subcutaneous Tissue/surgery , Subcutaneous Tissue/ultrastructure , Surface Properties , Titanium/chemistry , Zinc Oxide/chemistry
2.
Biomed Tech (Berl)
; 43 Suppl: 380-1, 1998.
Article
in German
| MEDLINE
| ID: mdl-9859408
Subject(s)
Durapatite , Osseointegration/physiology , Prosthesis Implantation , Animals , Male , Mice , Surface Properties
3.
Biomed Tech (Berl)
; 42 Suppl: 409-10, 1997.
Article
in German
| MEDLINE
| ID: mdl-9517213