[Prevalence and etiology of secondary amenorrhea in a selected Mexican population]. / Prevalencia y etiología de la amenorrea secundaria en una población mexicana escogida.

Studies performed upon american and european population indicate that secondary amenorrhea is associated to 3 months without menses, despite biases observed in age variation and intervals of apparition; nonetheless a 3 month lapse is the standard of reference to quality patients within mexican females. Hence, we investigated the prevalence of secondary amenorrhea among all females (n = 1099) that consulted in our clinic, grouped by age (15-50 yrs), time (months) of amenorrea and identifying the etiology when possible. The prevalence observed was 4.9% with major incidence of 4-12 months of amenorrhea duration (x 5.7 months) between 26-35 years of age. The three most common causes in order of frequency were: Hypothyroidism (14.8%); hiperandrogenism (12.9%) and pituitary adenoma (11.1%). It is concluded that the prevalence of secondary amenorrhea in our study resembled that found in the literature, although in this instance primary hyperthyroidism was the leading cause.

[Familial pituitary tumor with somatotropic compromise]. / Tumor hipofisario familiar de compromiso somatomamotrópico.

Pituitary adenoma, familiar type, with apparent affection over the involved somatomammotropin of secretion of growth hormone and prolactin, with dominant autosomic transmission, is described for the first time. It was seen that a couple of members without demonstrable tumour, showed clinical data (phenotype) of acromegaly. On investigation of histocompatibility antigens it was observed that the patients with tumour and other symptomatic ones, but without tumour, shared the same haplotypes, and so is very possible that investigation of HLA antigens in patients with pituitary tumour, contributes to better identify its nature and frequency.

[Costovertebral dysplasia]. / Displasia costovertebral.

Costovertebral dysplasia is characterized by dysmorphic dwarfism at the expense of the trunk, with typical costal and vertebral anomalies that cause displacement of the intrathoracic and intra-abdominal organs and reduced pulmonary function. There is a recessive severe variety manifested in the newborn and a rare dominant form which is more benign.

Displasia costovertebral. / Costovertebral dysplasia

La displasia costovertebral es una entidad caracterizada por enanismo dismorfico a expensas del torax, con alteraciones costales y vertebrales tipicas que ocasionan desplazamiento de los organos intraabdominales y funcion pulmonar disminuida. Existe una variedad severa que se manifiesta en el neonato, y una forma dominante mas leve

[Progressive fibrodysplasia assificans]. / Fibrodisplasia osificante progresiva.

A five years old patient with myositis ossificans progressiva is presented. This very rare disease is inherited as an autosomal dominant and it is characterized by an abnormality of the connective tissue, specifically, aponeurosis, fascias, tendons and ligaments; the muscle are secondarly affected.