Subject(s)
Heart Failure , Myocardial Infarction , Aged , Heart , Heart Failure/diagnosis , Heart Failure/surgery , Humans , ThrombectomyABSTRACT
A right atrial mass was discovered with transthoracic cardiac ultrasound in a complaint-free, 81-year-old man at his yearly cardiological checkup. Further investigation of the mass with transesophageal cardiac ultrasound showed a well-defined nodular mass of approximately 3 × 3 cm, in close proximity to the posterior wall of the right atrium. The patient underwent an F-FDG PET/CT, which showed a right atrial mass with very high FDG uptake, suggesting a malignant process. The mass was surgically removed, and anatomopathological assessment revealed an intimal sarcoma, which is a very malignant tumor and an extremely rare occurrence at this location.
Subject(s)
Fluorodeoxyglucose F18 , Heart Atria/diagnostic imaging , Positron Emission Tomography Computed Tomography , Sarcoma/diagnostic imaging , Aged, 80 and over , Biological Transport , Echocardiography , Fluorodeoxyglucose F18/metabolism , Humans , Male , Sarcoma/metabolismABSTRACT
Whereas effective strategies are available to treat acute cellular cardiac rejection, humoral rejection, also called vascular or antibody-mediated rejection, is more difficult to manage. Antibody-mediated (non-cellular) rejections (AMR) are rare and few successfully treated cases have been described in the literature. We report on a female patient, diagnosed with humoral rejection, leading to severe ventricular dysfunction and haemodynamic compromise, two months after transplantation. The patient received a combination therapy, consisting of plasmapheresis and immunoglobulins, which resulted in complete resolution of immunohistochemical signs of AMR. In this report, we will overview AMR and discuss several treatment modalities.
