[Monitoring of life-threatening infection pathogens in relation to the problem of prediction of critical situations]. / Monitoring vozbuditelei opasnykh infektsii v sviazi s problemoi prognozirovaniia kriticheskikh situatsii.

The epidemic situation in the context of many infectious diseases caused by bacteria is presently assessed as being poor in Russia and other countries. The spectrum of the pathogens that can deteriorate epidemic well-being is highly wide. The epidemic situation in terms of many infectious diseases, including those caused by such causative agents as Bacillus anthracis, Vibrio cholerae, Yersinia pestis, Francisella tularensis and others may deteriorate due to the emergence of their modified forms owing to their specific variability. The above generates the necessity of improving controlling measures or developing the techniques for monitoring the pathogens of infectious diseases, including those in the framework of international cooperation.

[Hybrid recombinant proteins: structure, properties and use]. / Gibridnye rekombinantnye belki: struktura , svoistva i primenenie.

The paper deals with the problem pertaining to immunotoxins which consist of two components, namely: catalytic (effector) and receptor-binding (ligand) ones. The immunotoxins are promising pharmaceutical drugs of a new generation, which are successfully used in clinical practice to treat tumor diseases, allergy, AIDS, and to transplant organs and tissues. Immunotoxins for the therapy of diabetes, autoimmune diseases, and bacterial, viral, and parasitic infections are being developed.

[Immunofluorescence study of H-2 antigens in early mouse embryogenesis]. / Immunofluorestsentnoe issledovanie H-2 antigenov v rannem émbriogeneze myshei.

The time of appearance and degree of expression were studied for antigens of the main locus of histocompatibility of the mouse embryos by indirect immunofluorescence. H-2 antigens appeared on the 5.5 day of embryogenesis on the cells of still undifferentiated rudiments of embryonic endoderm and ectoderm. By the 8th day of embryogenesis, rather intensice fluorescence of the cells of amnion, yolk sac and embryonic ectoderm was observed suggesting a marked expression of H-2 antigens during this period. The cells of trophoblast gave practically no positive reaction with anti-H-2-serum.