1.
Vopr Onkol
; 21(10): 77-88, 1975.
Article
in Russian
| MEDLINE
| ID: mdl-1189355
ABSTRACT
The function of: (see article), fits the tumors weight growth for all studied generations in both control and treated animals. Morphological studies show the transplantable tumors in A mice to lose their similarity to a spontaneous tumor--low differentiated adenocarcinoma. Meanwhile, the tumors in C3H mice have a high differentiation level which is typical for the original tumor. 1-nitroso-1-methylurea is very effective against the first generation of tumors in both strains of mice. The tumors response to the drug becomes weaker with further passages. 1-nitroso-1-methyl urea is superior to other nitrous derivatives when used in such tumor models as breast adenocarcinoma in C3H mice.
Subject(s)
Mammary Neoplasms, Experimental/physiopathology , Adenocarcinoma/drug therapy , Adenocarcinoma/physiopathology , Animals , Cell Transformation, Neoplastic/drug effects , Ethylnitrosourea/therapeutic use , Kinetics , Male , Mammary Neoplasms, Experimental/drug therapy , Mathematics , Methylnitrosourea/therapeutic use , Mice , Mice, Inbred A , Mice, Inbred C3H , Neoplasm Transplantation , Nitrosourea Compounds/therapeutic use , Time Factors
2.
Sov J Dev Biol
; 4(3): 224-30, 1974 May.
Article
in English
| MEDLINE
| ID: mdl-4842076
Subject(s)
Breeding , Parthenogenesis , Plants , Dimethyl Sulfoxide/pharmacology , Diploidy , Homozygote
3.
Cancer Chemother Rep
; 58(2): 135-48, 1974.
Article
in English
| MEDLINE
| ID: mdl-4830495
Subject(s)
Antineoplastic Agents/therapeutic use , Hodgkin Disease/drug therapy , Lung Neoplasms/drug therapy , Neoplasms, Experimental/drug therapy , Nitrosourea Compounds/therapeutic use , Animals , Antineoplastic Agents/administration & dosage , Antineoplastic Agents/adverse effects , Antineoplastic Agents/toxicity , Carcinoma 256, Walker/drug therapy , Carcinoma, Ehrlich Tumor/drug therapy , Dose-Response Relationship, Drug , Humans , Kinetics , Lymphoma/drug therapy , Mammary Neoplasms, Experimental/drug therapy , Mathematics , Mice , Nitrosourea Compounds/administration & dosage , Nitrosourea Compounds/adverse effects , Nitrosourea Compounds/toxicity , Rats , Rats, Inbred Strains , Regression Analysis , Sarcoma 180/drug therapy , Sarcoma, Experimental/drug therapy
4.
Vopr Onkol
; 18(9): 85-93, 1972.
Article
in Russian
| MEDLINE
| ID: mdl-4126161
Subject(s)
Antibiotics, Antineoplastic/pharmacology , Anal Gland Neoplasms/drug therapy , Animals , Bleomycin/administration & dosage , Bleomycin/adverse effects , Bleomycin/isolation & purification , Bleomycin/pharmacology , Bleomycin/therapeutic use , Body Temperature/drug effects , Dose-Response Relationship, Drug , Epithelium/drug effects , Female , Hematopoietic System/drug effects , Humans , Lung Neoplasms/drug therapy , Lymphoma/drug therapy , Male , Melanoma/drug therapy , Neoplasms/drug therapy , Penile Neoplasms/drug therapy , Skin/drug effects , Skin Neoplasms/drug therapy , Streptomyces , Structure-Activity Relationship , Uterine Cervical Neoplasms/drug therapy
5.
Vopr Onkol
; 17(11): 35-40, 1971.
Article
in Russian
| MEDLINE
| ID: mdl-5157638
6.
Vopr Onkol
; 16(5): 31-7, 1970 May.
Article
in Russian
| MEDLINE
| ID: mdl-4915916
Subject(s)
Antineoplastic Agents/therapeutic use , Neoplasms/drug therapy , Nitroso Compounds/therapeutic use , Adult , Antineoplastic Agents/administration & dosage , Antineoplastic Agents/adverse effects , Carcinoma/drug therapy , Colonic Neoplasms/drug therapy , Diarrhea/chemically induced , Eosinophilia/chemically induced , Hodgkin Disease/drug therapy , Humans , Leukopenia/chemically induced , Lung Neoplasms/drug therapy , Lymphatic Metastasis , Lymphoma, Large B-Cell, Diffuse/drug therapy , Male , Middle Aged , Nausea/chemically induced , Nitroso Compounds/administration & dosage , Nitroso Compounds/adverse effects , Pruritus/chemically induced , Stomach Neoplasms/drug therapy , Thrombocytopenia/chemically induced , Vomiting/chemically induced
7.
Vopr Onkol
; 16(2): 96-102, 1970.
Article
in Russian
| MEDLINE
| ID: mdl-4909274
Subject(s)
Hyperthermia, Induced , Neoplasms/therapy , Animals , Antineoplastic Agents/therapeutic use , Carcinoma, Brown-Pearce/therapy , Cell Line , Chemotherapy, Cancer, Regional Perfusion , Diathermy , Dogs , Endotoxins/therapeutic use , Female , HeLa Cells , Humans , In Vitro Techniques , Methods , Mice , Neoplasms, Experimental/therapy , Rabbits , Rats , Sarcoma 180/therapy , Sarcoma, Experimental/therapy , Uterine Cervical Neoplasms/therapy
8.
Vopr Onkol
; 16(11): 108-16, 1970.
Article
in Russian
| MEDLINE
| ID: mdl-4929044
Subject(s)
Neoplasms/drug therapy , Animals , Antineoplastic Agents/therapeutic use , Carcinoma, Brown-Pearce/drug therapy , Carcinoma, Ehrlich Tumor/drug therapy , Chlorambucil/therapeutic use , Cyclophosphamide/therapeutic use , Dactinomycin/therapeutic use , Humans , Hyperbaric Oxygenation , Leukemia L1210/drug therapy , Lymphoma/drug therapy , Methotrexate/therapeutic use , Mitomycins/therapeutic use , Vincristine/therapeutic use
9.
Vopr Onkol
; 16(3): 46-54, 1970.
Article
in Russian
| MEDLINE
| ID: mdl-5419650
10.
Izv Akad Nauk SSSR Biol
; 5: 752-8, 1969.
Article
in Russian
| MEDLINE
| ID: mdl-5372909
11.
Vopr Onkol
; 15(1): 92-104, 1969.
Article
in Russian
| MEDLINE
| ID: mdl-4185056
Subject(s)
Antineoplastic Agents/therapeutic use , Neoplasms/drug therapy , Antimetabolites/therapeutic use , Antineoplastic Agents/administration & dosage , Antineoplastic Agents/adverse effects , Body Temperature , Chemotherapy, Cancer, Regional Perfusion , Female , Hematologic Diseases/chemically induced , Hematologic Diseases/prevention & control , Hormones/therapeutic use , Humans , Lymphatic System/immunology , Neoplasms/immunology , Ovarian Neoplasms/drug therapy , Palliative Care , Uterine Neoplasms/drug therapy
12.
Vopr Onkol
; 15(5): 91, 1969.
Article
in Russian
| MEDLINE
| ID: mdl-5360151
13.
Izv Akad Nauk SSSR Biol
; 4: 475-84, 1968.
Article
in Russian
| MEDLINE
| ID: mdl-5707055
Subject(s)
Sarcoma 180/drug therapy , Sarcoma 37/drug therapy , Animals , Antineoplastic Agents/therapeutic use , Kinetics , Mice
14.
Vopr Onkol
; 14(1): 102-9, 1968.
Article
in Russian
| MEDLINE
| ID: mdl-4873226
15.
Izv Akad Nauk SSSR Biol
; 4: 517-26, 1967.
Article
in Russian
| MEDLINE
| ID: mdl-6076375
16.
Vopr Onkol
; 13(2): 93-9, 1967.
Article
in Russian
| MEDLINE
| ID: mdl-5245210
Subject(s)
Antineoplastic Agents/therapeutic use , Amino Acids/antagonists & inhibitors , Animals , Antineoplastic Agents/adverse effects , Carcinosarcoma/drug therapy , Diarrhea/chemically induced , Dogs , Feeding and Eating Disorders/chemically induced , Fibrosarcoma/drug therapy , Guinea Pigs , Humans , Lymphoma, Non-Hodgkin/drug therapy , Mammary Neoplasms, Experimental/drug therapy , Mice , Neoplasms, Experimental/drug therapy , Plasmacytoma/drug therapy , Rats , Sarcoma, Experimental/drug therapy
17.
Vrach Delo
; 9: 133-5, 1966 Sep.
Article
in Russian
| MEDLINE
| ID: mdl-6001245
18.
Vopr Onkol
; 12(4): 50-5, 1966 Apr.
Article
in Russian
| MEDLINE
| ID: mdl-4300193
Subject(s)
Dichlorodiphenyldichloroethane/therapeutic use , Neoplasms, Experimental/drug therapy , Animals , Carcinoma 256, Walker/drug therapy , Carcinoma, Ehrlich Tumor/drug therapy , Carcinoma, Hepatocellular/drug therapy , Injections, Subcutaneous , Liver Neoplasms , Mammary Neoplasms, Experimental/drug therapy , Melanoma/drug therapy , Mice , Neoplasm Transplantation , Rats , Sarcoma 180/drug therapy , Sarcoma 37/drug therapy
19.
Vopr Onkol
; 12(11): 58-61, 1966.
Article
in Russian
| MEDLINE
| ID: mdl-4975408
20.
Biofizika
; 11(4): 616-20, 1966.
Article
in Russian
| MEDLINE
| ID: mdl-4300335