1.
Clin Biochem
; 42(13-14): 1490-2, 2009 Sep.
Article
in English
| MEDLINE
| ID: mdl-19524564
ABSTRACT
OBJECTIVES: To examine the effect of blood anticoagulation type on the myeloperoxidase (MPO) concentration. DESIGN AND METHODS: MPO was measured in EDTA-plasma and matched heparin-plasma and serum samples collected from healthy volunteers. RESULTS: MPO concentrations in heparin-plasma and serum were higher than in EDTA-plasma (both P<0.001). MPO in EDTA-plasma was not significantly correlated with MPO in either heparin-plasma or serum. CONCLUSIONS: For MPO measurements, EDTA-plasma is the preferred specimen as it appears unaffected by ex vivo release of MPO from leukocytes.
Subject(s)
Anticoagulants/pharmacology , Peroxidase/blood , Plasma/drug effects , Serum/drug effects , Adult , Blood Preservation/methods , Edetic Acid/pharmacology , Female , Heparin/pharmacology , Humans , Male , Plasma/enzymology , Serum/enzymology , Temperature
2.
Biochim Biophys Acta
; 1781(6-7): 336-43, 2008.
Article
in English
| MEDLINE
| ID: mdl-18534202