[Danazol in the treatment of menometrorrhagia in patients with mitral prosthesis treated with warfarin]. / II danazolo nel trattamento delle menometrorragie di pazienti con protesi mitralica in terapia con warfarin.

The difficulty in the treatment of patients undergoing Warfarin therapy for mitral stenosis, is underlined and cases treated with Danazol in sideropenic anaemia caused by menometrorrhagia are reported.

[Perinatal fetal distress: correlations between Apgar score at birth and assay of CK-BB in umbilical cord blood]. / In tema di sofferenza fetale perinatale: correlazioni tra punteggio di Apgar alla nascita e dosaggio del CK-BB nel sangue di cordone ombelicale.

32 newborn infant's umbilical cord blood CK-BB activity was tested at birth. 14 of them had a superior to 7 Apgar score at first and fifth minutes, whereas 18 newborn infant Apgar score was inferior to 7. The CK-BB activity was significantly higher in newborn infants having a low Apgar score at birth. A low Apgar score at first and fifth minutes together with a high CK-BB activity must be considered a nervous trouble signal and a warning in order to look after children's psychomotor skills more strictly and individual neurological damage.

[Monitoring of high-risk pregnancies (author's transl)]. / Monitoraggio delle gravidanze a rischio.

The AA. have monitored 202 patients affected by several pathological conditions and at different stages of their pregnancies. Among them, 173 were pregnancies without complications. Monitoring was performed on the basis of the following 3 indices: HCS radioimmunological assay, total plasmatic estriol, and vaginal cytology. Results show, as demonstrated in the graphs and the final discussion, that already within the first weeks of gestation the pathological cases under observation presented marked modifications of the indices studied when compared to controls.

[Rate meaning of estriol-dosage in the pregnant wife pointing out the phoetus development (author's transl)]. / Il valore del dosaggio dell'estriolo nella donna gravida quale indice dello sviluppo del feto

The AA. point out the meaning of the urinary estriol dosage in high risk pregnancy. The screening must be frequent and regular, with constant growing curve all time along. A sudden fall down of the rate shows a severe malaise of the phoetus and proper therapy is badly needed. Extemporary screenings dont supply any sufficient knowledge.