ABSTRACT
We describe the case of a 79-year-old woman with mitral insufficiency and a double-orifice mitral valve (DOMV), discovered by echocardiography. Transthoracic echocardiography showed two insufficiency jets. Transesophageal echocardiography revealed a DOMV. Each orifice was provided with a subvalvular apparatus. No associated congenital abnormalities were present. Our case demonstrates that even in elderly patients with a double regurgitant jet, DOMV should be suspected and assessed by transesophageal echocardiography.
Subject(s)
Echocardiography, Transesophageal , Mitral Valve Insufficiency/complications , Mitral Valve/abnormalities , Aged , Echocardiography , Female , Humans , Mitral Valve/diagnostic imaging , Mitral Valve Insufficiency/diagnostic imagingABSTRACT
1-(4-Isopropylthiophenyl)-2-n-octylaminopropanol (suloctidil, Sulocton), a drug introduced into clinical practice for the treatment of cerebral and peripheral vascular insufficiency and its complications, has been shown to decrease blood hyperviscosity after long-term treatment in diabetic patients. Suloctidil was particularly effective in lowering measured blood viscosity at high shear rate (230 s-1). At low shear rate (0.77 s-1) a decreasing effect was also observed but reached a statistically significant level only after one month. Since neither total plasma fibrinogen levels nor red blood cell deformability were modified by suloctidil treatment, its lowering effect on blood hyperviscosity could be due to a hitherto unrecognized mechansim of action.
Subject(s)
Blood Viscosity/drug effects , Diabetes Mellitus/blood , Erythrocytes/drug effects , Fibrinogen/metabolism , Propanolamines/therapeutic use , Suloctidil/therapeutic use , Adult , Aged , Diabetes Complications , Double-Blind Method , Erythrocytes/pathology , Female , Hematocrit , Humans , Male , Middle Aged , Time FactorsSubject(s)
Heart Neoplasms/diagnosis , Hemangioma/diagnosis , Adolescent , Age Factors , Female , Heart Auscultation , Heart Neoplasms/diagnostic imaging , Heart Neoplasms/pathology , Heart Neoplasms/surgery , Hemangioma/diagnostic imaging , Hemangioma/pathology , Hemangioma/surgery , Humans , Postoperative Complications , Tomography, X-RayABSTRACT
The resting electrocardiograms of 30 cyclists currently involved in competitive sport were compared with those of an equal number of healthy controls matched for age, height, and weight. The cyclists had significantly lower heart rates, longer PQ,QRS, and QTc intervals, higher T waves in lead II, left axis deviation of the T wave, higher R waves in the right and deeper S waves in the left praecordial leads, and deeper S waves in the right and higher R waves in the left praecordial leads.The possible significance of these findings should be assessed by prolonged prospective studies in athletes and untrained control subjects.
