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1.
J Otolaryngol Head Neck Surg ; 51(1): 30, 2022 Jul 28.
Article in English | MEDLINE | ID: mdl-35902904

ABSTRACT

BACKGROUND: Intra-operative internal carotid artery (ICA) injury during transnasal endoscopic surgery is a potentially catastrophic event. Such an injury is life-threatening in the immediate setting, with a reported peri-operative mortality rate of 10%. Nasal packing, muscle patches, direct vessel closure, and endovascular techniques have been described as useful strategies for managing ICA bleeds. The objective of this study was to develop a formalized management protocol for intra-operative ICA injury through engagement with a multi-disciplinary panel. METHODS: A modified Delphi method including literature review, iterative rounds of stakeholder feedback, and expert panel discussions was used to develop a management protocol for ICA injury during transnasal endoscopic surgery. The 10-person multi-disciplinary panel included otolaryngologists, neurosurgeons, interventional neuroradiologists, anesthesiologists, and operating room nursing staff. RESULTS: After three rounds of stakeholder engagement with the expert panel, consensus was reached on important elements to include within the protocol. The protocol was divided in three categories: Alert, Control, and Transfer. 'Alert' focusses on early communication with anesthesia and nursing staff. 'Control' focusses on techniques to expose the injury and obtain hemostasis or adequate tamponade. Lastly, 'Transfer' describes the process of contacting neuro-interventional radiology and safely transferring the patient. A one-page handout of the protocol was developed for placement in operating theatres. CONCLUSION: Due to the life-threatening nature of ICA injury, it is imperative that endoscopic sinus and skull base surgeons are prepared to manage this complication. Using a modified Delphi method with a multidisciplinary expert panel, a protocol for management of intra-operative ICA injury was developed.


Subject(s)
Carotid Artery Injuries , Carotid Artery, Internal , Carotid Artery Injuries/etiology , Carotid Artery Injuries/surgery , Carotid Artery, Internal/surgery , Delphi Technique , Endoscopy/adverse effects , Endoscopy/methods , Humans , Skull Base/surgery
2.
Am J Rhinol Allergy ; 34(4): 519-531, 2020 Jul.
Article in English | MEDLINE | ID: mdl-32208748

ABSTRACT

BACKGROUND: Acute bacterial rhinosinusitis (ABRS) is a highly prevalent disease that is treated by a variety of specialties, including but not limited to, family physicians, emergency physicians, otolaryngology-head and neck surgeons, infectious disease specialists, and allergy and immunologists. Unfortunately, despite high-quality guidelines, variable and substandard care continues to be demonstrated in the treatment of ABRS. OBJECTIVE: This study aimed to develop ABRS-specific quality indicators (QIs) to evaluate the diagnosis and management that reduces symptoms, improves quality of life, and prevents complications. METHODS: A guideline-based approach, proposed by Kötter et al., was used to develop QIs for ABRS. Candidate indicators (CIs) were extracted from 4 guiding documents and evaluated using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) tool. Each CI and its supporting evidence was summarized and reviewed by an expert panel based on validity, reliability, and feasibility of measurement. Final QIs were selected from CIs utilizing the modified RAND/University of California at Los Angeles appropriateness methodology. RESULTS: Twenty-nine CIs were identified after literature review and evaluated by our panel. Of these, 5 CIs reached consensus as being appropriate QIs, with 1 requiring additional discussion. After a second round of evaluations, the panel selected 7 QIs as appropriate measures of high-quality care. CONCLUSION: This study proposes 7 QIs for the diagnosis and management of patients with ABRS. These QIs can serve multiple purposes, including documenting the quality of care; comparing institutions and providers; prioritizing quality improvement initiatives; supporting accountability, regulation, and accreditation; and determining pay for performance initiatives.


Subject(s)
Quality Indicators, Health Care/standards , Rhinitis/epidemiology , Sinusitis/epidemiology , Acute Disease , Canada/epidemiology , Consensus , Evidence-Based Practice , Humans , Practice Guidelines as Topic , Quality Improvement , Quality of Life , Reimbursement, Incentive , Reproducibility of Results , Rhinitis/diagnosis , Sinusitis/diagnosis
3.
Oper Neurosurg (Hagerstown) ; 17(2): 132-142, 2019 08 01.
Article in English | MEDLINE | ID: mdl-30768130

ABSTRACT

BACKGROUND: The role of expanded endonasal endoscopic surgery for primary and recurrent craniopharyngioma is not yet fully established. OBJECTIVE: To report and evaluate our experience with the endoscopic endonasal approach (EEA) for the resection of primary and recurrent craniopharyngiomas. METHODS: This is a retrospective cohort analysis of 43 consecutive EEA procedures in 40 patients operated from September 2006 to February 2012 for suprasellar craniopharyngiomas. In 21 patients (48.8%) the disease was recurrent. We have assessed the surgical results, visual, endocrinological, and functional outcomes and resection rates in this patient cohort. RESULTS: At presentation, 31 (72.1%) patients had visual deficits, 15 patients (34.9%) complained of headaches, 25 patients (58.1%) had anterior pituitary insufficiency, and 14 (32.5%) had diabetes insipidus. Total resection was achieved in 44.2% surgeries, of which 77.3% were in primary lesions and 9.5% in recurrent lesions (P < .001). Vision improved in 92.6% patients and worsened in 2.3%. Complications other than vision were encountered in 25.6% including 9/43 cerebrospinal fluid leak, 2/43 meningitis. A total of 51.9% of patients with preoperative residual anterior pituitary function had new anterior pituitary deficiencies and 42.8% had new diabetes insipidus. There was no mortality. Six patients (14%) had recurrence of disease during the follow-up period (mean 56.8 mo), 5 of which required repeat surgery. CONCLUSION: The EEA can be integrated in the overall management of both primary and recurrent craniopharyngiomas with good results; however, in our series recurrent surgery was associated with significantly lower rates of gross total resection.


Subject(s)
Craniopharyngioma/surgery , Neuroendoscopy/methods , Pituitary Neoplasms/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Child , Female , Humans , Male , Middle Aged , Neoplasm Recurrence, Local/surgery , Postoperative Complications/etiology , Retrospective Studies , Treatment Outcome , Young Adult
4.
Int Forum Allergy Rhinol ; 8(12): 1369-1379, 2018 12.
Article in English | MEDLINE | ID: mdl-29999592

ABSTRACT

BACKGROUND: Chronic rhinosinusitis (CRS) has been identified as a high-priority disease category for quality improvement. To this end, this study aimed to develop CRS-specific quality indicators (QIs) to evaluate diagnosis and management that relieves patient discomfort, improves quality of life, and prevents complications. METHODS: A guideline-based approach, proposed in 2012 by Kötter et al. was used to develop QIs for CRS. Candidate indicators (CIs) were extracted from 3 practice guidelines and 1 international consensus statement on the diagnosis and management of CRS. Guidelines were evaluated using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) tool. Each CI and its supporting evidence was summarized and reviewed by an expert panel based on validity, reliability, and feasibility of measurement. Final QIs were selected from CIs utilizing the modified RAND Corporation-University of California, Los Angeles (RAND/UCLA) appropriateness methodology. RESULTS: Thirty-nine CIs were identified after literature review and evaluated by our panel. Of these, 9 CIs reached consensus as being appropriate QIs, with 4 requiring additional discussion. After a second round of evaluations, the panel selected 9 QIs as appropriate measures of high-quality care. CONCLUSION: This study proposes 9 QIs for the diagnosis and management of patients with CRS. These QIs can serve multiple purposes, including documenting the quality of care; comparing institutions and providers; prioritizing quality improvement initiatives; supporting accountability, regulation, and accreditation; and determining pay-for-performance initiatives.


Subject(s)
Endoscopy , Nasal Polyps/diagnosis , Quality Indicators, Health Care/statistics & numerical data , Rhinitis, Allergic/diagnosis , Sinusitis/diagnosis , Canada/epidemiology , Chronic Disease , Consensus , Expert Testimony , Humans , Nasal Polyps/epidemiology , Nasal Polyps/therapy , Outcome and Process Assessment, Health Care , Quality Improvement , Quality of Life , Reimbursement, Incentive , Reproducibility of Results , Rhinitis, Allergic/epidemiology , Rhinitis, Allergic/therapy , Sinusitis/epidemiology , Sinusitis/therapy
5.
Am J Rhinol Allergy ; 31(4): 216-221, 2017 Jul 01.
Article in English | MEDLINE | ID: mdl-28716171

ABSTRACT

BACKGROUND: Previous studies describe the financial burden of chronic rhinosinusitis (CRS) from the perspective of third-party payers, but, to our knowledge, none analyze the costs borne by patients (i.e., out-of-pocket expenses [OOPE]). Furthermore, this burden has not been previously investigated in the context of a publicly funded health care system. OBJECTIVE: The purpose of this study was to characterize the financial impact of CRS on patients, specifically by evaluating its associated OOPEs and the perceived financial burden. The secondary aim was to determine the factors predictive of OOPEs and perceived burden. METHODS: Patients with CRS at a tertiary care sinus center completed a self-administered questionnaire that assessed their socioeconomic characteristics, disease-specific quality of life (22-item Sino-Nasal Outcome Test [SNOT-22]), workdays missed due to CRS, perceived financial burden, and direct medical and nonmedical OOPEs over a 12-month period. Total OOPEs were calculated from the sum of direct medical and nonmedical OOPEs. Regression analyses determined factors predictive of OOPEs and the perceived burden. RESULTS: A total of 84 patients completed the questionnaires. After accounting for health insurance coverage and the median direct medical, direct nonmedical, and total OOPEs per patient over a 12-month period were Canadian dollars (CAD) $336.00 (2011) [U.S. $339.85], CAD $129.87 [U.S. $131.86], and CAD $607.10 [U.S. $614.06], respectively. CRS resulted in an average of 20.6 workdays missed over a 12-month period. Factors predictive of a higher financial burden included younger age, a greater number of previous sinus surgeries, <80% health insurance coverage, residing out of town, and higher SNOT-22 scores. CONCLUSION: Total OOPEs incurred from the treatment of CRS may amount to CAD $607.10 [U.S. $614.06] per patient per year, within the context of a single-payer health care system. Managing clinicians should be aware of patient groups with a greater perceived financial burden and consider counseling them on strategies to offset expenses, including obtaining travel grants, using telemedicine for follow-up assessments, providing drug samples, and streamlining diagnostic testing with medical visits.


Subject(s)
Cost of Illness , Health Expenditures/statistics & numerical data , Rhinitis/epidemiology , Sinusitis/epidemiology , Canada , Chronic Disease , Female , Humans , Male , Quality of Life , Surveys and Questionnaires , Young Adult
6.
J Craniofac Surg ; 27(6): 1532-4, 2016 Sep.
Article in English | MEDLINE | ID: mdl-27428902

ABSTRACT

With the use and efficacy of the vascularized nasoseptal flap, its indications are also expanding. Due to its relative ease of harvesting and no significant impairment in the long-term sinonasal quality of life, the flap has been used for a number of other purposes apart from its originally proposed use in reconstruction of the anterior cranial fossa, sella, and the clivus. Its use may negate the need of another incision to obtain fat or fascia. The authors describe the case of a 47-year-old lady who underwent endoscopic excision of a medially placed orbital intraconal hemangioma who presented to us with very poor vision in the left eye. The large medial orbital defect was reconstructed with a vascularized pedicled nasoseptal flap from the ipsilateral side. The patient made an excellent visual and sino-nasal recovery. This patient highlights a unique use for the proliferating indications for the use of the nasoseptal flap.


Subject(s)
Nasal Septum/surgery , Orbit/surgery , Plastic Surgery Procedures/methods , Surgical Flaps/surgery , Eye Diseases/surgery , Female , Hemangioma/surgery , Humans , Middle Aged
7.
J Craniofac Surg ; 27(4): e348-50, 2016 Jun.
Article in English | MEDLINE | ID: mdl-27171958

ABSTRACT

Chronic rhinosinusitis (CRS) is a common health problem in the Western world. CRS is classified as CRS with (CRSwNP) and without (CRSsNP) nasal polyps. A less common third type is allergic fungal sinusitis, which often presents with polyps and, not infrequently, skull base erosion. Most patients are successfully managed with maximal medical therapy or endoscopic approaches. There are currently no reports of CRSwNPs resulting in fibro-osseous thickening and proptosis in the English literature. As such, the authors report a case of a 33-year-old man who underwent a craniofacial resection with drilling of the hyperostosed bone, which led to resolution of the proptosis and nasal symptoms. In an era where endoscopic surgery is the standard surgical approach for CRSwNP, this case highlights the need for open skullbase approaches for this condition due to the extensive and recalcitrant nature of the disease. While the majority of patients can be dealt with endoscopically, the authors highlight the importance of having the open approach in the otolaryngologists' armamentarium for patients of recalcitrant and extensive CRSwNP.


Subject(s)
Craniotomy/methods , Exophthalmos/etiology , Exophthalmos/surgery , Nasal Polyps/surgery , Rhinitis/surgery , Sinusitis/surgery , Adult , Chronic Disease , Endoscopy/methods , Humans , Magnetic Resonance Imaging , Male , Skull Base/surgery
8.
J Clin Neurosci ; 22(11): 1733-41, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26275331

ABSTRACT

We compare the outcomes and postoperative MRI changes of endoscopic endonasal (EEA) and bifrontal craniotomy (BFC) approaches for olfactory groove meningiomas (OGM). All patients who underwent either BFC or EEA for OGM were eligible. Matched pairs were created by matching tumor volumes of an EEA patient with a BFC patient, and matching the timing of the postoperative scans. The tumor dimensions, peritumoral edema, resectability issues, and frontal lobe changes were recorded based on preoperative and postoperative MRI. Postoperative fluid-attenuated inversion recovery (FLAIR) hyperintensity and residual cystic cavity (porencephalic cave) volume were compared using univariable and multivariable analyses. From a total of 70 patients (46 EEA, 24 BFC), 10 matched pairs (20 patients) were created. Three patients (30%) in the EEA group and two (20%) in the BFC had postoperative cerebrospinal fluid leaks (p=0.61). Gross total resections were achieved in seven (70%) of the EEA group and nine (90%) of the BFC group (p=0.26), and one patient from each group developed a recurrence. On postoperative MRI, there was no significant difference in FLAIR signal volumes between EEA and BFC approaches (6.9 versus 13.3 cm(3); p=0.17) or in porencephalic cave volumes (1.7 versus 5.0 cm(3); p=0.11) in univariable analysis. However, in a multivariable analysis, EEA was associated with less postoperative FLAIR change (p=0.02) after adjusting for the volume of preoperative edema. This study provides preliminary evidence that EEA is associated with quantifiable improvements in postoperative frontal lobe imaging.


Subject(s)
Craniotomy/methods , Meningeal Neoplasms/surgery , Meningioma/surgery , Neuroendoscopy/methods , Adult , Female , Frontal Lobe/pathology , Humans , Magnetic Resonance Imaging/methods , Male , Matched-Pair Analysis , Meningeal Neoplasms/pathology , Meningioma/pathology , Middle Aged , Neoplasm Recurrence, Local/surgery , Treatment Outcome
9.
Thyroid ; 25(11): 1224-34, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26131603

ABSTRACT

BACKGROUND: It is of critical clinical importance to select accurately for surgery thyroid nodules at risk for malignancy and avoid surgery on those that are benign. Using alterations in subcellular localization for seven putative biomarker proteins (identified by proteomics), this study aimed to define a specific combination of proteins in surgical tissues that could distinguish benign from malignant nodules to assist in future surgical selection by fine-needle aspiration biopsy (FNAB). METHODS: Immunohistochemical subcellular localization (IHC) analyses of seven proteins were retrospectively performed on surgical tissues (115 benign nodules and 114 papillary-based thyroid carcinomas [TC]), and a risk model biomarker panel was developed and validated. The biomarker panel efficacy was verified in 50 FNAB formalin-fixed and paraffin-embedded cell blocks, and 26 cytosmears were prepared from fresh surgically resected thyroid nodules. RESULTS: Selection modeling using these proteins resulted in nuclear phosphoglycerate kinase 1 (PGK1) loss and nuclear Galectin-3 overexpression as the best combination for distinguishing TC from benign nodules (area under the curve [AUC] 0.96 and 0.95 in test and validation sets, respectively). A computed malignancy score also accurately identified TC in benign and indeterminate nodules (test and validation sets: AUC 0.94, 0.90; specificity 98%, 99%). Its efficacy was confirmed in surgical FNAB cell blocks and cytosmears. CONCLUSION: Using surgical tissues, it was observed that a combination of PGK1 and Galectin-3 had high efficiency for distinguishing benign from malignant thyroid nodules and could improve surgical selection for TC among indeterminate nodules. Further validation in prospective preoperative FNAB will be required to confirm such a clinical application.


Subject(s)
Carcinoma, Papillary/diagnosis , Thyroid Gland/metabolism , Thyroid Neoplasms/diagnosis , Thyroid Nodule/diagnosis , Adult , Aged , Aged, 80 and over , Biomarkers/metabolism , Biopsy, Fine-Needle , Carcinoma, Papillary/metabolism , Carcinoma, Papillary/pathology , Diagnosis, Differential , Female , Humans , Immunohistochemistry , Male , Middle Aged , Retrospective Studies , Sensitivity and Specificity , Subcellular Fractions/metabolism , Thyroid Gland/pathology , Thyroid Neoplasms/metabolism , Thyroid Neoplasms/pathology , Thyroid Nodule/metabolism , Thyroid Nodule/pathology , Young Adult
10.
J Neurol Surg B Skull Base ; 76(2): 129-144, 2015 Mar.
Article in English | MEDLINE | ID: mdl-28856080

ABSTRACT

Objective Skull base tumors are associated with quality of life (QOL) changes. A qualitative case-study approach may help better understand patients' experiences. Methods A total of 34 skull base surgery patients were selected into focus groups using a criterion-based maximum variation sampling strategy from a sampling frame of 138 patients. Eight groups were organized based on a factorial design of surgical approach (endoscopic/pen) and tumor location (anterior/central). Data were analyzed using a conceptual framework. Qualitative analysis was performed on focus group transcripts to identify major themes and determine if surgical approach or tumor location had differential effects on QOL. Concepts were quantitatively tallied from written workbooks. Results The 34 participants (19 men, 15 women; mean age: 48 years, standard deviation: 14 years) had mixed reactions to their diagnosis ranging from relief to fear. Participants reported physical and nonphysical changes in QOL with some variation in physical complaints by tumor location. Several major themes emerged from the analysis. Skull base tumors are associated with fear and frustration, loss of physical senses and self-identity, social isolation, and coping mechanisms. Conclusions Skull base surgery may impact patients' lives. Qualitative study of patient experiences can provide rich information to better understand this disease.

11.
J Otolaryngol Head Neck Surg ; 42: 6, 2013 Jan 31.
Article in English | MEDLINE | ID: mdl-23663897

ABSTRACT

BACKGROUND: As the indications for expanded endonasal approaches continue to evolve, alternative reconstructive techniques are needed to address increasingly complex surgical skull base defects. In the absence of the nasoseptal flap, we describe our experience with the posterior pedicle inferior turbinate flap (PPITF) in skull base reconstruction. DESIGN: Case series. SETTING: Academic tertiary care centre. METHODS: Patients who underwent reconstruction of the skull base with the PPITF were identified. Medical records were reviewed for demographic, presentation, treatment, follow-up, surgical and outcomes data. MAIN OUTCOME MEASURES: Flap survival, adequacy of seal, and complications. RESULTS: Two patients with residual/recurrent pituitary adenomas met the inclusion criteria. The nasoseptal flap was unavailable in each case due to a prior septectomy. Salvage of the original nasoseptal flap was not possible, as it did not provide adequate coverage of the resultant defect due to contraction from healing. All PPITFs healed uneventfully and covered the entire defect. No complications were observed in the early post-operative period. Endoscopic techniques and limitations of the PPITF are also discussed. CONCLUSIONS: Our clinical experience supports the PPITF to be a viable alternative for reconstruction of the skull base in the absence of the nasoseptal flap.


Subject(s)
Adenoma/surgery , Pituitary Neoplasms/surgery , Plastic Surgery Procedures/methods , Skull Base/surgery , Surgical Flaps , Adult , Endoscopy , Female , Humans , Middle Aged , Retrospective Studies
12.
Head Neck ; 35(9): 1221-31, 2013 Sep.
Article in English | MEDLINE | ID: mdl-22987281

ABSTRACT

BACKGROUND: Several quality of life (QOL) instruments exist for skull base pathology, however, there have been no attempts to appraise and systematically review these instruments. METHODS: We systematically reviewed MEDLINE, EMBASE, Central, AMED, Health and Psychosocial Instruments, and PsychoInfo for anterior or central skull base QOL instruments to January 2010. We queried experts, bibliographies, and meeting proceedings from the North American Skull Base Society from 2005 to 2009. Included instruments were evaluated for instrument characteristics, item generation and reduction, field testing, and measurement properties using predefined criteria. RESULTS: We identified 9 QOL instruments: 7 measuring QOL for pituitary pathology, 1 for midface pathology, and 1 for anterior skull base pathology. Eight of the 9 instruments have had some psychometric testing. None demonstrated all of the predefined psychometric properties. CONCLUSIONS: There are several QOL instruments for patients with skull base pathology. None of these instruments met all predefined requirements, and further instrument development is needed.


Subject(s)
Quality of Life , Sickness Impact Profile , Skull Base Neoplasms/psychology , Skull Base Neoplasms/surgery , Skull Base/pathology , Humans , Psychometrics , Quality of Life/psychology , Surveys and Questionnaires
13.
Head Neck ; 35(4): 493-9, 2013 Apr.
Article in English | MEDLINE | ID: mdl-22581692

ABSTRACT

BACKGROUND: Skull base tumors are associated with physical symptoms that vary depending on location and surgical approach. METHODS: Skull base surgery patients (n = 138) were retrospectively reviewed and physical symptoms were quantified. Patients were divided into 4 groups by surgical approach (open, endoscopic) and tumor location (anterior, central). Multivariate analyses determined odds for symptom development. RESULTS: Patients with anterior lesions presented with more nasal symptoms compared to those with central lesions (63% vs 6.8%; p < .001). Those with central lesions presented with more neurologic (41.1% vs 12.3%; p < .001) and endocrine symptoms (19.2% vs 0%; p < .001). Three of 4 groups experienced a reduction in neurologic and visual symptoms after surgery. One group (endoscopic/central) experienced a reduction in endocrine and an increase in nasal symptoms. Anterior tumors (p = .02) and endoscopic approaches (p = .002) predicted increased nasal morbidity. CONCLUSION: Physical morbidity from skull base tumors may vary based on tumor location and surgical approach.


Subject(s)
Endoscopy/methods , Neurosurgical Procedures/methods , Postoperative Complications/epidemiology , Skull Base Neoplasms/pathology , Skull Base/pathology , Adult , Aged , Endoscopy/adverse effects , Female , Humans , Male , Middle Aged , Morbidity , Neurosurgical Procedures/adverse effects , Retrospective Studies , Skull Base/surgery , Skull Base Neoplasms/diagnosis , Skull Base Neoplasms/surgery
14.
Surg Endosc ; 27(2): 454-61, 2013 Feb.
Article in English | MEDLINE | ID: mdl-22833264

ABSTRACT

BACKGROUND: Advanced image-guidance systems allowing presentation of three-dimensional navigational data in real time are being developed enthusiastically for many medical procedures. Other industries, including aviation and the military, have noted that shifting attention toward such compelling assistance has detrimental effects. Using the detection rate of unexpected findings, we assess whether inattentional blindness is significant in a surgical context and evaluate the impact of on-screen navigational cuing with augmented reality. METHODS: Surgeons and trainees performed an endoscopic navigation exercise on a cadaveric specimen. The subjects were randomized to either a standard endoscopic view (control) or an AR view consisting of an endoscopic video fused with anatomic contours. Two unexpected findings were presented in close proximity to the target point: one critical complication and one foreign body (screw). Task completion time, accuracy, and recognition of findings were recorded. RESULTS: Detection of the complication was 0/15 in the AR group versus 7/17 in the control group (p = 0.008). Detection of the screw was 1/15 (AR) and 7/17 (control) (p = 0.041). Recognition of either finding was 12/17 for the control group and 1/15 for the AR group (p < 0.001). Accuracy was greater for the AR group than for the control group, with the median distance from the target point measuring respectively 2.10 mm (interquartile range [IQR], 1.29-2.37) and 4.13 (IQR, 3.11-7.39) (p < 0.001). CONCLUSION: Inattentional blindness was evident in both groups. Although more accurate, the AR group was less likely to identify significant unexpected findings clearly within view. Advanced navigational displays may increase precision, but strategies to mitigate attentional costs need further investigation to allow safe implementation.


Subject(s)
Attention , Endoscopy/standards , Surgery, Computer-Assisted/methods , Cadaver , Humans , User-Computer Interface
15.
Laryngoscope ; 122(9): 1933-42, 2012 Sep.
Article in English | MEDLINE | ID: mdl-22777574

ABSTRACT

OBJECTIVES/HYPOTHESIS: Anterior and central skull base lesions and their surgical treatment (endoscopic or open approaches) can affect quality of life. A disease-specific instrument is needed to compare quality of life for different surgical approaches. STUDY DESIGN: Items were generated using a composite strategy consisting of chart review, systematic review of skull base instruments, expert interviews, and qualitative analysis of patient focus groups. A cross-sectional survey study was performed to reduce items based on an item impact score. METHODS: Charts of 138 patients who underwent skull base surgery were reviewed to identify physical items and domains. Five experts were interviewed for item and domain identification. Thirty-four patients were recruited into eight focus groups based on their surgical approach (open or endoscopic) and tumor location (anterior or central). Items were generated using a composite approach and then reduced into a final questionnaire using item impact scores. RESULTS: Chart review identified 47 physical items. Systematic review revealed nine relevant instruments with 217 relevant items. Experts identified 11 domains with 69 additional items. Qualitative analysis of focus groups generated 49 items. A total of 382 items were identified and reduced to 77 items after eliminating overlapping and irrelevant items. Further item reduction using item impact scores yielded 41 items. CONCLUSIONS: The Skull Base Inventory is a disease-specific quality-of-life instrument. Psychometric properties have yet to be tested. It may serve to compare quality of life for endoscopic or open procedures.


Subject(s)
Endoscopy/methods , Neurosurgical Procedures/methods , Quality of Life , Skull Base Neoplasms/psychology , Skull Base Neoplasms/surgery , Activities of Daily Living , Adaptation, Psychological , Adult , Aged , Cranial Fossa, Anterior/surgery , Cranial Fossa, Middle/surgery , Cross-Sectional Studies , Female , Focus Groups , Humans , Male , Middle Aged , Monitoring, Physiologic/methods , Postoperative Complications/epidemiology , Postoperative Complications/physiopathology , Psychometrics , Skull Base/pathology , Skull Base/surgery , Skull Base Neoplasms/pathology , Surveys and Questionnaires
16.
Int Forum Allergy Rhinol ; 2(5): 405-10, 2012.
Article in English | MEDLINE | ID: mdl-22644966

ABSTRACT

BACKGROUND: Due to proximity to critical structures, the need for spatial awareness during endoscopic sinus surgery (ESS) is essential. We have developed an augmented, real-time image-guided surgery (ART-IGS) system that provides live navigational data and proximity alerts to the operating surgeon during ablation. We wished to test the hypothesis that task workload would be reduced when using this technology. METHODS: A trial involved 8 otolaryngology residents and fellows performing ESS on cadaveric specimens; 1 side in a conventional method (control) and 1 side with ART-IGS. After computed tomography scanning, anatomical contouring, and registration of the head, a three-dimensional (3D) virtual endoscopic view, ablative tool tracking, and proximity alerts were enabled. Each subject completed ESS tasks and rated their workload during and after the exercise using the National Aeronautics and Space Administration (NASA) Task Load Index (TLX). A questionnaire and open feedback interview were completed after the procedure. RESULTS: There was a significant reduction in mental demand, temporal demand, effort, and frustration when using the ART-IGS system in comparison to the control (p < 0.02). Perceived performance was increased (p = 0.02). Most subjects agreed that the system was sufficiently accurate, caused minimal interruption, and increased confidence. Optical tracking line-of-sight issues were frequently cited as the main limitation early in the study; however, this was largely resolved. CONCLUSION: ART-IGS reduces task workload for trainees performing ESS. Live navigation and alert zones may be a valuable intraoperative teaching aid.


Subject(s)
Endoscopy/methods , Paranasal Sinuses/surgery , Surgery, Computer-Assisted/methods , Workload , Cadaver , Computer Systems/statistics & numerical data , Endoscopy/instrumentation , Humans , Paranasal Sinuses/diagnostic imaging , Radiography , Surgery, Computer-Assisted/instrumentation , Task Performance and Analysis
17.
Int Forum Allergy Rhinol ; 2(1): 20-6, 2012.
Article in English | MEDLINE | ID: mdl-22311837

ABSTRACT

BACKGROUND: Surgical training models are being increasingly used to provide an environment for surgical trainees to improve their skills without risk to patients. This study uses previously validated, inexpensive, low-fidelity training models to determine how pretraining affects endoscopic sinus surgery (ESS) skills. METHODS: Fourteen Otolaryngology residents were randomized to 1 of 2 groups that were stratified for training level. The first group took part in a pretraining session where they practiced on all 5 different modules whereas the second group did not receive any pretraining. The following day, all participants took part in a cadaveric ESS course. Participants were instructed to complete a set of tasks and their performances were videotaped. The videos were then evaluated using a Global Rating Scale (GRS) and a Task-Specific Checklist (TSC). The performances of those who trained using the models were compared to the performances of those who did not. RESULTS: The intervention (pretraining) group performed better than the nonintervention (no pretraining) group on the cadaveric ESS tasks (p < 0.05). As well, there was a statistical difference between the senior residents who had the pretraining with the simulator models performing better than those who did not. CONCLUSION: The modules appear to have made a positive impact on ESS skills. These low-cost, easily-constructed training modules have the potential to be integrated into Otolaryngology-Head and Neck Surgery resident training. Assessment of long-term training effects with a larger number of participants is planned for future studies.


Subject(s)
Clinical Competence/standards , Endoscopy/education , Internship and Residency , Models, Anatomic , Otolaryngology/education , Paranasal Sinuses/surgery , Cadaver , Endoscopy/standards , Female , Humans , Male , Observer Variation , Videotape Recording
18.
Otolaryngol Clin North Am ; 44(5): 1185-200, 2011 Oct.
Article in English | MEDLINE | ID: mdl-21978901

ABSTRACT

The goals of treatment of skull base neoplasms are to maximize oncologic outcomes and optimize functional outcomes. Several studies have investigated the former, but fewer examine the latter. This article reviews the available evidence for several functional outcomes, including endocrine, nasal, neurologic, visual, and quality of life outcomes for both endoscopic and open approaches. The quality of evidence for each outcome is compared for endoscopic and open approaches using the Oxford Centre for Evidence-based Medicine guidelines, and recommendations are made. Future longitudinal comparative outcome studies are needed to better delineate the functional status of patients undergoing skull base surgery.


Subject(s)
Endoscopy , Skull Base Neoplasms/surgery , Skull Base/surgery , Endoscopy/adverse effects , Evidence-Based Medicine , Humans , Postoperative Complications , Quality of Life , Treatment Outcome
19.
Head Neck ; 33(4): 547-51, 2011 Apr.
Article in English | MEDLINE | ID: mdl-20824807

ABSTRACT

BACKGROUND: Nasal morbidity following skull base surgery necessitates follow-up for postoperative care. We describe nasal morbidity following endoscopic skull base surgery. METHODS: Patient and operative data and postoperative subjective and objective measures of morbidity were prospectively collected for 1 year. Time to absence of crusting and remucosalization were determined. Risk factor analyses for crusting and nasal discharge were performed. RESULTS: Nasal crusting (98%) and discharge (46%) were the most common postoperative symptoms. Median time to absence of crusting was 101.0 days, with longer times for complex cases (p = .033) but not for patients with septal flaps or fat grafts. Median time to remucosalization after nasoseptal flap was 89.0 days. There were no risk factors for crusting, although surgical complexity was a risk factor for postoperative discharge (odds ratio [OR] = 5.17). CONCLUSIONS: Nasal morbidity following endoscopic skull base surgery is common and may be affected by surgical complexity and use of the nasoseptal flap.


Subject(s)
Endoscopy/adverse effects , Nose Diseases/etiology , Skull Base/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Cohort Studies , Female , Humans , Male , Middle Aged , Risk Factors , Surgical Flaps , Young Adult
20.
Int Forum Allergy Rhinol ; 1(1): 55-63, 2011.
Article in English | MEDLINE | ID: mdl-22287309

ABSTRACT

BACKGROUND: Fibro-osseous lesions of the paranasal sinuses are an uncommon heterogeneous group of lesions with variable clinical presentation. It is unclear whether these lesions directly cause symptoms or secondarily obstruct the sinuses with resultant rhinosinusitis. We have used an expectant management approach in selected patients that includes observation with serial scans or endoscopic sinus surgery (ESS) to improve the outflow tract of the affected sinus without resection of the lesion. The purpose of this work is to review our experience with management of paranasal sinus fibro-osseous lesions. METHODS: Retrospective chart review from 1997 to 2009. RESULTS: A total of 44 patients were identified in this study. There were 19 (43%) osteoma and 25 (57%) fibrous dysplasia cases. The presenting symptoms were mainly sinonasal with headaches (36%), pain/pressure (19%), and nasal obstruction (17%). Two patients (4.5%) presented with proptosis and diplopia. Five (11%) patients had associated nasal polyps. The diagnosis was an incidental finding in seventeen (38%) cases. Twenty-two (50%) patients were managed conservatively with serial computed tomography (CT) scans to monitor for interval growth over a mean interval of 41.8 months (range, 13-130 months). There were 2 patients in the observation group with CT scan evidence of interval growth with an increase in size of 1 mm and 9 mm over 130 and 36 months, respectively. Twelve symptomatic patients (27%) underwent ESS without resection of the lesion, with symptomatic improvement in 11 patients (92%). Four patients (9%) underwent endoscopic biopsy to attain histological diagnosis. Six (13%) patients in this study had resection of their lesion with 5 of the patients having symptomatic improvement following resection. CONCLUSION: In patients with fibro-osseous lesions, we support an expectant management approach of asymptomatic patients with observation and serial imaging, treating selected symptomatic patients with ESS and resection of the lesion in patients with orbital complications, progressive growth of the lesion, or persistent symptoms.


Subject(s)
Bone Neoplasms/surgery , Endoscopy/methods , Fibroma, Ossifying/surgery , Fibrous Dysplasia of Bone/surgery , Osteoma/surgery , Paranasal Sinus Neoplasms/surgery , Adolescent , Adult , Aged , Bone Neoplasms/diagnostic imaging , Chronic Disease , Female , Fibroma, Ossifying/diagnostic imaging , Fibrous Dysplasia of Bone/diagnostic imaging , Humans , Incidental Findings , Male , Middle Aged , Osteoma/diagnostic imaging , Paranasal Sinus Neoplasms/diagnostic imaging , Retrospective Studies , Rhinitis/etiology , Sinusitis/etiology , Tomography, X-Ray Computed , Treatment Outcome , Watchful Waiting , Young Adult
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