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3.
Med Microbiol Immunol ; 169(2): 75-81, 1981.
Article in English | MEDLINE | ID: mdl-6163956

ABSTRACT

Staining of lymphocytes from scrapie-infected STU mice with FITC-labelled anti-mouse Ig revealed disturbances in the capping process when compared with lymphocytes from mock-infected animals. Quantitative evaluation indicates that 10-15% of cells from scrapie-infected animals show an altered capping behaviour. These phenomena are discussed with special reference to the role of the lymphoreticular system in early scrapie agent replication.


Subject(s)
Antibodies, Anti-Idiotypic/immunology , Immunologic Capping , Lymphocytes/immunology , Scrapie/immunology , Animals , Female , Mice , Sheep , Spleen/cytology , Staining and Labeling
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