ABSTRACT
Genetic study of rats showed the possibility of registration of the minor doses of the inside and outside irradiation. The postmiosis mutations, number of reciprocal translocations in spermatogonia may be used for indexation of the effects.
Subject(s)
Radiation Injuries, Experimental/genetics , Animals , Cesium Radioisotopes/adverse effects , Chromosome Aberrations , Dose-Response Relationship, Radiation , Female , Genes, Dominant/radiation effects , Genes, Lethal/radiation effects , Male , Mutation , Radiation Injuries, Experimental/epidemiology , Rats , Regression Analysis , Spermatogonia/radiation effects , Time FactorsABSTRACT
In experiments with rats it was shown that with equal absorbed doses after single injection of 137Cs and local X-irradiation of testes the mutation yield in gametes was different when tested by the frequency of dominant lethals and half-lethals, reciprocal translocations, univalents, and chromosome fragments. A higher efficiency of whole-body irradiation as compared to local exposure of testes, with respect to genetic damages induction, and the statistically significant increase in the number of the damages during a long period of time after cessation of the absorbed dose formation indicated that indirect effects of whole-body irradiation contributed to the injury to hereditary structures and permitted to estimate approximately their contribution (up to 50%).
