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Peptides ; 55: 65-78, 2014 May.
Article in English | MEDLINE | ID: mdl-24548568

ABSTRACT

Plant immune responses involve a wide diversity of physiological reactions that are induced by the recognition of pathogens, such as hypersensitive responses, cell wall modifications, and the synthesis of antimicrobial molecules including antimicrobial peptides (AMPs). These proteinaceous molecules have been widely studied, presenting peculiar characteristics such as conserved domains and a conserved disulfide bond pattern. Currently, many AMP classes with diverse modes of action are known, having been isolated from a large number of organisms. Plant AMPs comprise an interesting source of studies nowadays, and among these there are reports of different classes, including defensins, albumins, cyclotides, snakins and several others. These peptides have been widely used in works that pursue human disease control, including nosocomial infections, as well as for agricultural purposes. In this context, this review will focus on the relevance of the structural-function relations of AMPs derived from plants and their proper use in applications for human health and agribusiness.


Subject(s)
Anti-Bacterial Agents/therapeutic use , Antimicrobial Cationic Peptides/therapeutic use , Plant Proteins/therapeutic use , Agriculture , Amino Acid Motifs , Animals , Anti-Bacterial Agents/chemistry , Antimicrobial Cationic Peptides/chemistry , Antimicrobial Cationic Peptides/genetics , Bacterial Infections/drug therapy , Crops, Agricultural/genetics , Crops, Agricultural/microbiology , Disease Resistance , Humans , Models, Molecular , Plant Diseases/microbiology , Plant Proteins/chemistry , Plant Proteins/genetics , Plants, Genetically Modified
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