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1.
Patol Fiziol Eksp Ter ; (2): 20-2, 1996.
Article in Russian | MEDLINE | ID: mdl-8754139

ABSTRACT

Neutrophilokine, a latex-activated neutrophilic secretory product, was tested for effects on the body's response to immobilization stress. Preadministration of neutrophilokine decreased the magnitude of post-stress changes: neutrophilic leukocytosis, lymphopenia, and stress-induced ulcerogenesis in the gastric mucosa. It is concluded that triple administration of neutrophilokine induces adaptation to immobilization stress.


Subject(s)
Adaptation, Physiological/drug effects , Neutrophils/drug effects , Stress, Physiological/drug therapy , Animals , Bone Marrow/drug effects , Rats
2.
Fiziol Zh Im I M Sechenova ; 81(12): 88-94, 1995 Dec.
Article in Russian | MEDLINE | ID: mdl-8754033

ABSTRACT

Repeated immobilisation induced a biphasic dynamic of the blood system stress sensitivity: first, an increased neutrophilia, lymphocytopenia, bone marrow granulocyte depletion and activation of the erythropoiesis; second, a restitution of mature granulocyte-monocyte cells number in the bone marrow and accumulation of neutrophils in the spleen.


Subject(s)
Adaptation, Physiological , Stress, Physiological/blood , Animals , Blood Cell Count , Bone Marrow/pathology , Chronic Disease , Female , Male , Rats , Restraint, Physical , Spleen/pathology , Stress, Physiological/pathology , Stress, Physiological/physiopathology , Time Factors
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