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Rev Med Chir Soc Med Nat Iasi ; 86(2): 319-21, 1982.
Article in Romanian | MEDLINE | ID: mdl-25588262

ABSTRACT

The mechanism of reaction-between the zinc atom of alcohol dehydrogenase and 6 pyrazolone and azopyrazolone compounds, type 1-(4'-carboxyphenyl)-3-methyl-4(1"azo-4"-ethoxy-phenyl)-5-pyrazolone, synthetized by the authors, is studied. For elucidating the "in vivo" phenomenon, the complexes of these compounds were synthetized with zinc atoms, the IR specters and quantitative chemical analyses being followed. Based on these, the possibilities of complexing the zinc from the ADH molecule by these compounds are discussed.


Subject(s)
Acetic Acid/chemical synthesis , Alcohol Dehydrogenase/chemistry , Alcohol Deterrents/chemical synthesis , Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis , Pyrazolones/chemical synthesis , Zinc Acetate/chemical synthesis , Zinc/chemistry , Catalysis , Spectrophotometry, Infrared
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