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1.
Diagnostics (Basel) ; 14(11)2024 Jun 04.
Article in English | MEDLINE | ID: mdl-38893709

ABSTRACT

The purpose of the study was to assess the performance of readers in diagnosing thoracic anomalies on standard chest radiographs (CXRs) with and without a deep-learning-based AI tool (Rayvolve) and to evaluate the standalone performance of Rayvolve in detecting thoracic pathologies on CXRs. This retrospective multicentric study was conducted in two phases. In phase 1, nine readers independently reviewed 900 CXRs from imaging group A and identified thoracic abnormalities with and without AI assistance. A consensus from three radiologists served as the ground truth. In phase 2, the standalone performance of Rayvolve was evaluated on 1500 CXRs from imaging group B. The average values of AUC across the readers significantly increased by 15.94%, with AI-assisted reading compared to unaided reading (0.88 ± 0.01 vs. 0.759 ± 0.07, p < 0.001). The time taken to read the CXRs decreased significantly, by 35.81% with AI assistance. The average values of sensitivity and specificity across the readers increased significantly by 11.44% and 2.95% with AI-assisted reading compared to unaided reading (0.857 ± 0.02 vs. 0.769 ± 0.02 and 0.974 ± 0.01 vs. 0.946 ± 0.01, p < 0.001). From the standalone perspective, the AI model achieved an average sensitivity, specificity, PPV, and NPV of 0.964, 0.844, 0.757, and 0.9798. The speed and performance of the readers improved significantly with AI assistance.

2.
Acad Radiol ; 2023 Nov 21.
Article in English | MEDLINE | ID: mdl-37993303

ABSTRACT

RATIONALE AND OBJECTIVES: To evaluate the standalone performance of a deep learning (DL) based fracture detection tool on extremity radiographs and assess the performance of radiologists and emergency physicians in identifying fractures of the extremities with and without the DL aid. MATERIALS AND METHODS: The DL tool was previously developed using 132,000 appendicular skeletal radiographs divided into 87% training, 11% validation, and 2% test sets. Stand-alone performance was evaluated on 2626 de-identified radiographs from a single institution in Ohio, including at least 140 exams per body region. Consensus from three US board-certified musculoskeletal (MSK) radiologists served as ground truth. A multi-reader retrospective study was performed in which 24 readers (eight each of emergency physicians, non-MSK radiologists, and MSK radiologists) identified fractures in 186 cases during two independent sessions with and without DL aid, separated by a one-month washout period. The accuracy (area under the receiver operating curve), sensitivity, specificity, and reading time were compared with and without model aid. RESULTS: The model achieved a stand-alone accuracy of 0.986, sensitivity of 0.987, and specificity of 0.885, and high accuracy (> 0.95) across stratification for body part, age, gender, radiographic views, and scanner type. With DL aid, reader accuracy increased by 0.047 (95% CI: 0.034, 0.061; p = 0.004) and sensitivity significantly improved from 0.865 (95% CI: 0.848, 0.881) to 0.955 (95% CI: 0.944, 0.964). Average reading time was shortened by 7.1 s (27%) per exam. When stratified by physician type, this improvement was greater for emergency physicians and non-MSK radiologists. CONCLUSION: The DL tool demonstrated high stand-alone accuracy, aided physician diagnostic accuracy, and decreased interpretation time.

3.
Geriatr Psychol Neuropsychiatr Vieil ; 17(4): 415-422, 2019 12 01.
Article in French | MEDLINE | ID: mdl-31848128

ABSTRACT

Because virtual reality seems to be increasingly considered in different medical fields, the objective of this study is to define the optimal conditions for its use in a population of elderly women with breast cancer. By using a questionnaire, we evaluated the interest but also the immersive aspirations and preferences of elderly women with regard to this innovative device, taking into account the possible changes with age (60-65 years; 66-69, 70 and over). Surprisingly, older people - whatever the age group - are particularly favorable to virtual reality without actually having experienced it. The patients primarily chose immersion in a natural environment (with a marked preference for mountain landscapes) accompanied by musical background or even guided relaxation. However, because they judged important to remain focused on the treatments, the patients especially expect VR to regulate their negative emotions (lowering anxiety) and to allow them to escape from the painful contingencies of the real. Thus, virtual reality must take them into a magical world, which is more salient than to distract them or make them laugh. The distracting power, commonly associated with VR, does not seem to be the most popular reason to use with seniors facing medical care.


Subject(s)
Breast Neoplasms , Virtual Reality , Aged , Breast Neoplasms/psychology , Breast Neoplasms/therapy , Female , Humans , Middle Aged
4.
Phys Rev Lett ; 119(7): 070401, 2017 Aug 18.
Article in English | MEDLINE | ID: mdl-28949669

ABSTRACT

We demonstrate that perturbative expansions for quantum many-body systems can be rephrased in terms of tensor networks, thereby providing a natural framework for interpolating perturbative expansions across a quantum phase transition. This approach leads to classes of tensor-network states parametrized by few parameters with a clear physical meaning, while still providing excellent variational energies. We also demonstrate how to construct perturbative expansions of the entanglement Hamiltonian, whose eigenvalues form the entanglement spectrum, and how the tensor-network approach gives rise to order parameters for topological phase transitions.

5.
J Phys Chem Lett ; 8(11): 2469-2474, 2017 Jun 01.
Article in English | MEDLINE | ID: mdl-28513178

ABSTRACT

The search for functional materials is currently hindered by the difficulty to find significant correlation between constitutive properties of a material and its functional properties. In the case of amorphous materials, the diversity of local structures, chemical composition, impurities and mass densities makes such a connection difficult to be addressed. In this Letter, the relation between refractive index and composition has been investigated for amorphous AlOx materials, including nonstoichiometric AlOx, emphasizing the role of structural defects and the absence of effect of the band gap variation. It is found that the Newton-Drude (ND) relation predicts the refractive index from mass density with a rather high level of precision apart from some structures displaying structural defects. Our results show especially that O- and Al-based defects act as additive local disturbance in the vicinity of band gap, allowing us to decouple the mass density effects from defect effects (n = n[ND] + Δndefect).

6.
Phys Rev Lett ; 115(21): 217202, 2015 Nov 20.
Article in English | MEDLINE | ID: mdl-26636869

ABSTRACT

We introduce a quantum dimer model on the hexagonal lattice that, in addition to the standard three-dimer kinetic and potential terms, includes a competing potential part counting dimer-free hexagons. The zero-temperature phase diagram is studied by means of quantum Monte Carlo simulations, supplemented by variational arguments. It reveals some new crystalline phases and a cascade of transitions with rapidly changing flux (tilt in the height language). We analyze perturbatively the vicinity of the Rokhsar-Kivelson point, showing that this model has the microscopic ingredients needed for the "devil's staircase" scenario [Eduardo Fradkin et al. Phys. Rev. B 69, 224415 (2004)], and is therefore expected to produce fractal variations of the ground-state flux.

7.
Sci Rep ; 5: 8961, 2015 Mar 10.
Article in English | MEDLINE | ID: mdl-25753657

ABSTRACT

This paper presents the low cost electrodeposition of a transparent and conductive chlorine doped ZnO layer with performances comparable to that produced by standard vacuum processes. First, an in-depth study of the defect physics by ab-initio calculation shows that chlorine is one of the best candidates to dope the ZnO. This result is experimentally confirmed by a complete optical analysis of the ZnO layer deposited in a chloride rich solution. We demonstrate that high doping levels (>10(20) cm(-3)) and mobilities (up to 20 cm(2) V(-1) s(-1)) can be reached by insertion of chlorine in the lattice. The process developed in this study has been applied on a CdS/Cu(In,Ga)(Se,S)2 p-n junction produced in a pilot line by a non vacuum process, to be tested as solar cell front contact deposition method. As a result efficiency of 14.3% has been reached opening the way of atmospheric production of Cu(In,Ga)(Se,S)2 solar cell.

8.
J Phys Chem Lett ; 5(7): 1117-25, 2014 Apr 03.
Article in English | MEDLINE | ID: mdl-26274458

ABSTRACT

Defect tolerance is the tendency of a semiconductor to keep its properties despite the presence of crystallographic defects. Scientific understanding of the origin of defect tolerance is currently missing. Here we show that semiconductors with antibonding states at the top of the valence band are likely to be tolerant to defects. Theoretical calculations demonstrate that Cu3N with antibonding valence band maximum has shallow intrinsic defects and no surface states, in contrast to GaN with bonding valence band maximum. Experimental measurements indicate shallow native donors and acceptors in Cu3N thin films, leading to 10(16)-10(17) cm(-3) doping with either electrons or holes depending on the growth conditions. The experimentally measured bipolar doping and the solar-matched optical absorption onset (1.4 eV) make Cu3N a promising candidate absorber for photovoltaic and photoelectrochemical solar cells, despite the calculated indirect fundamental band gap (1.0 eV). These conclusions can be extended to other materials with antibonding character of the valence band, defining a class of defect-tolerant semiconductors for solar energy conversion applications.

9.
Phys Rev Lett ; 110(14): 147203, 2013 Apr 05.
Article in English | MEDLINE | ID: mdl-25167030

ABSTRACT

We examine the zero-temperature phase diagram of the two-dimensional Levin-Wen string-net model with Fibonacci anyons in the presence of competing interactions. Combining high-order series expansions around three exactly solvable points and exact diagonalizations, we find that the non-Abelian doubled Fibonacci topological phase is separated from two nontopological phases by different second-order quantum critical points, the positions of which are computed accurately. These trivial phases are separated by a first-order transition occurring at a fourth exactly solvable point where the ground-state manifold is infinitely many degenerate. The evaluation of critical exponents suggests unusual universality classes.

10.
Phys Rev Lett ; 106(10): 107203, 2011 Mar 11.
Article in English | MEDLINE | ID: mdl-21469828

ABSTRACT

We investigate the stability of the topological phase of the toric code model in the presence of a uniform magnetic field by means of variational and high-order series expansion approaches. We find that when this perturbation is strong enough, the system undergoes a topological phase transition whose first- or second-order nature depends on the field orientation. When this transition is of second order, it is in the Ising universality class except for a special line on which the critical exponent driving the closure of the gap varies continuously, unveiling a new topological universality class.

11.
Phys Rev Lett ; 104(13): 136401, 2010 Apr 02.
Article in English | MEDLINE | ID: mdl-20481897

ABSTRACT

We use hybrid functionals and restricted self-consistent GW, state-of-the-art theoretical approaches for quasiparticle band structures, to study the electronic states of delafossite Cu(Al,In)O2, the first p-type and bipolar transparent conductive oxides. We show that a self-consistent GW approximation gives remarkably wider band gaps than all the other approaches used so far. Accounting for polaronic effects in the GW scheme we recover a very nice agreement with experiments. Furthermore, the modifications with respect to the Kohn-Sham bands are strongly k dependent, which makes questionable the common practice of using a scissor operator. Finally, our results support the view that the low energy structures found in optical experiments, and initially attributed to an indirect transition, are due to intrinsic defects in the samples.

12.
Phys Rev Lett ; 104(5): 056401, 2010 Feb 05.
Article in English | MEDLINE | ID: mdl-20366776

ABSTRACT

We present a first-principles study of the electronic properties of CuIn(S,Se){2} (CIS) using state-of-the-art self-consistent GW and hybrid functionals. The calculated band gap depends strongly on the anion displacement u, an internal structural parameter that measures lattice distortion. This contrasts with the observed stability of the band gap of CIS solar panels under operating conditions, where a relatively large dispersion of values for u occurs. We solve this apparent paradox considering the coupled effect on the band gap of copper vacancies and lattice distortions. The correct treatment of d electrons in these materials requires going beyond density functional theory, and GW self-consistency is critical to evaluate the quasiparticle gap and the valence band maximum.

13.
Psychol Neuropsychiatr Vieil ; 6(4): 245-57, 2008 Dec.
Article in French | MEDLINE | ID: mdl-19087906

ABSTRACT

According to social psychology, the relationship between the subject and his environment is constantly mediatized by the interaction with others. This article presents a set of researches on ageing which adopt this epistemological approach. A first part is dedicated to studies which focus on the identity of the old subjects. The second part presents works that are devoted to social categorization of the aged. Finally, the third part is dedicated to researches on social representations of the aged. With no claim to exhaustiveness, this paper underlines the interest of a psychosocial approach of aging.


Subject(s)
Adaptation, Psychological/physiology , Aging/psychology , Environment , Humans , Social Environment , Stereotyping
14.
Phys Rev E Stat Nonlin Soft Matter Phys ; 78(2 Pt 1): 021106, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18850785

ABSTRACT

The spectrum of the Lipkin-Meshkov-Glick model is exactly derived in the thermodynamic limit by means of a spin-coherent-state formalism. In the first step, a classical analysis allows one to distinguish between four distinct regions in the parameter space according to the nature of the singularities arising in the classical energy surface; these correspond to spectral critical points. The eigenfunctions are then analyzed more precisely in terms of the associated roots of the Majorana polynomial, leading to exact expressions for the density of states in the thermodynamic limit. Finite-size effects are also analyzed, leading in particular to logarithmic corrections near the singularities occurring in the spectrum. Finally, we also compute expectation values of the spin operators in a semiclassical analysis in order to illustrate some subtle effects occurring in one region of the parameter space.

15.
Phys Rev Lett ; 101(2): 025701, 2008 Jul 11.
Article in English | MEDLINE | ID: mdl-18764198

ABSTRACT

We establish a relation between several entanglement properties in the Lipkin-Meshkov-Glick model, which is a system of mutually interacting spins embedded in a magnetic field. We provide analytical proofs that the single-copy entanglement and the global geometric entanglement of the ground state close to and at criticality behave as the entanglement entropy. These results are in deep contrast to what is found in one- dimensional spin systems where these three entanglement measures behave differently.

16.
Phys Rev Lett ; 100(17): 177204, 2008 May 02.
Article in English | MEDLINE | ID: mdl-18518331

ABSTRACT

We analyze the effect of local spin operators in the Kitaev model on the honeycomb lattice. We show, in perturbation around the isolated-dimer limit, that they create Abelian anyons together with fermionic excitations which are likely to play a role in experiments. We derive the explicit form of the operators creating and moving Abelian anyons without creating fermions and show that it involves multispin operations. Finally, the important experimental constraints stemming from our results are discussed.

17.
Phys Rev Lett ; 100(5): 057208, 2008 Feb 08.
Article in English | MEDLINE | ID: mdl-18352424

ABSTRACT

We study the gapped phase of the Kitaev model on the honeycomb lattice using perturbative continuous unitary transformations. The effective low-energy Hamiltonian is found to be an extended toric code with interacting anyons. High-energy excitations are emerging free fermions which are composed of hard-core bosons with an attached string of spin operators. The excitation spectrum is mapped onto that of a single particle hopping on a square lattice in a magnetic field. We also illustrate how to compute correlation functions in this framework. The present approach yields analytical perturbative results in the thermodynamical limit without using the Majorana or the Jordan-Wigner fermionization initially proposed to solve this problem.

18.
Phys Rev Lett ; 99(5): 050402, 2007 Aug 03.
Article in English | MEDLINE | ID: mdl-17930734

ABSTRACT

A method based on the analysis of the Majorana polynomial roots is introduced to compute the spectrum of the Lipkin-Meshkov-Glick model in the thermodynamical limit. A rich structure made of four qualitatively different regions is revealed in the parameter space, whereas the ground state study distinguishes between only two phases.

19.
Nano Lett ; 7(6): 1717-22, 2007 Jun.
Article in English | MEDLINE | ID: mdl-17516680

ABSTRACT

We show that a semiconductor membrane made of two thin layers of opposite (n- and p-) doping can perform electrically tunable ion current rectification and filtering in a nanopore. Our model is based on the solution of the 3D Poisson equation for the electrostatic potential in a double-cone nanopore combined with a transport model. It predicts that, for appropriate biasing of the membrane-electrolyte system, transitions from ohmic behavior to sharp rectification with vanishing leakage current are achievable. Furthermore, ion current rectifying and filtering regimes of the nanopore correspond to different charge states in the p-n membrane, which can be tuned with appropriate biasing of the n- and p- layers.


Subject(s)
Membranes, Artificial , Models, Chemical , Models, Molecular , Nanostructures/chemistry , Semiconductors , Computer Simulation , Computer-Aided Design , Electric Conductivity , Electrochemistry/instrumentation , Electrochemistry/methods , Nanostructures/ultrastructure , Nanotechnology/instrumentation , Nanotechnology/methods , Particle Size
20.
Phys Rev Lett ; 97(22): 220402, 2006 Dec 01.
Article in English | MEDLINE | ID: mdl-17155781

ABSTRACT

We present a perturbative method to compute the ground state entanglement entropy for interacting systems. We apply it to a collective model of mutually interacting spins in a magnetic field. At the quantum critical point, the entanglement entropy scales logarithmically with the subsystem size, the system size, and the anisotropy parameter. We determine the corresponding scaling prefactors and evaluate the leading finite-size correction to the entropy. Our analytical predictions are in perfect agreement with numerical results.

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