ABSTRACT
Ionizing radiation plays a key role in the adaptation of an individual organism to environmental pollution, at the same time, it has biological effects that depend on radiation intensity or dose rate (DR). Although the effect of DR has been studied in vitro, the phenomenon known as the inverse effect of DR, which indicates as it decreases that the induction of damage is greater, has not been widely studied in vivo. The present study is aimed to test 0.5 and 1 Gy in somatic cells of the wing of D. melanogaster, administered at 5.4 or 34.3 Gy/h and from 0.037 to 0.3 mM of CrO3 as conditioning treatment. No changes were found in larva-to-adult viability. A protective as well as a cross effect of pre-exposure to different DR and CrO3 concentrations against genetic damage induced by 20 Gy or 1 mM CrO3 was evident.
Subject(s)
Chromium Compounds/pharmacology , Drosophila melanogaster/genetics , Wings, Animal/cytology , Animals , Culture Media, Conditioned , DNA Damage/drug effects , Dose-Response Relationship, Radiation , Drosophila melanogaster/drug effects , Drosophila melanogaster/radiation effects , Female , Radiation Tolerance , Radiation, Ionizing , Wings, Animal/drug effects , Wings, Animal/radiation effectsABSTRACT
A fatal case of aortic valve endocarditis due to Abiotrophia defectiva was reported in Brazil. An overview of cases of endocarditis and other human infections related to A. defectiva in developing countries was also accomplished.
