1.
Clin Transl Oncol
; 26(7): 1806, 2024 Jul.
Article
in English
| MEDLINE
| ID: mdl-38758387
2.
Clin Transl Oncol
; 21(12): 1583-1623, 2019 Dec.
Article
in English
| MEDLINE
| ID: mdl-30949930
ABSTRACT
Progresses in multimodal treatments have significantly improved the outcomes for childhood cancer. Nonetheless, for about one-third of patients with Ewing sarcoma, rhabdomyosarcoma, or osteosarcoma steady remission has remained intangible. Thus, new biomarkers to improve early diagnosis and the development of precision-targeted medicine remain imperative. Over the last decade, remarkable progress has been made in the basic understanding of miRNAs function and in interpreting the contribution of their dysregulation to cancer development and progression. On this basis, this review focuses on what has been learned about the pivotal roles of miRNAs in the regulation of key genes implicated in childhood sarcomas.