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1.
Phys Med Biol ; 60(14): 5497-511, 2015 Jul 21.
Article in English | MEDLINE | ID: mdl-26133567

ABSTRACT

We investigate the improvement from the use of high-Z CdTe sensors for pre-clinical K-edge imaging with the hybrid pixel detectors XPAD3. We compare XPAD3 chips bump bonded to Si or CdTe sensors in identical experimental conditions. Image performance for narrow energy bin acquisitions and contrast-to-noise ratios of K-edge images are presented and compared. CdTe sensors achieve signal-to-noise ratios at least three times higher than Si sensors within narrow energy bins, thanks to their much higher detection efficiency. Nevertheless Si sensors provide better contrast-to-noise ratios in K-edge imaging when working at equivalent counting statistics, due to their better estimation of the attenuation coefficient of the contrast agent. Results are compared to simulated data in the case of the XPAD3/Si detector. Good agreement is observed when including charge sharing between pixels, which have a strong impact on contrast-to-noise ratios in K-edge images.


Subject(s)
Biosensing Techniques/instrumentation , Cadmium Compounds/chemistry , Image Processing, Computer-Assisted/methods , Phantoms, Imaging , Photons , Silicon/chemistry , Tellurium/chemistry , Tomography, X-Ray Computed/methods , Algorithms , Biosensing Techniques/methods , Humans , Radiographic Image Interpretation, Computer-Assisted/methods , Signal-To-Noise Ratio
2.
J Synchrotron Radiat ; 14(Pt 1): 151-7, 2007 Jan.
Article in English | MEDLINE | ID: mdl-17211083

ABSTRACT

Results obtained using a hybrid pixel photon-counting detector in powder diffraction experiments are presented. The detector works at room temperature and its dynamic response ranges from 0.01 photons pixel(-1) s(-1) up to 10(6) photons pixel(-1) s(-1). The pixel sizes are 0.33 mm x 0.33 mm for a total area of 68 mm x 68 mm. On recording high-resolution diffraction patterns of powders, a reduction of the experimental time by more than a factor of 20 is obtained without loss of data quality. The example of an X-zeolite shows that such detectors can be used for very demanding anomalous experiments. In situ experiments of quenching liquid oxides show that frames of 0.01 s can be achieved for studying such processes.


Subject(s)
Photons , Powder Diffraction/instrumentation , Radiometry/instrumentation , Signal Processing, Computer-Assisted/instrumentation , Transducers , Equipment Design , Equipment Failure Analysis , Pilot Projects , Powder Diffraction/methods , Radiation Dosage , Radiometry/methods , Semiconductors
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