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1.
J Pharm Bioallied Sci ; 13(Suppl 2): S1624-S1627, 2021 Nov.
Article in English | MEDLINE | ID: mdl-35018042

ABSTRACT

INTRODUCTION: The aim of this in vitro study was to compare the frictional forces produced by three types of ligatures (conventional elastic ligatures, unconventional elastic ligatures, and tooth-colored ligature wire) on ceramic bracket and stainless steel brackets with 0.016 nickeltitanium (NiTi) archwire in the dry state. MATERIALS AND METHODS: Twenty each stainless steel brackets and ceramic brackets (0.022 slot central incisor brackets) were mounted on the acrylic block. This assembly was mounted on the Instron machine with the crossheads moving upward at a speed of 10 mm/min in the upper jaw of the Instron machine, one acrylic block with hook and a straight length of 0.016 NiTi wire was attached to it. This wire was ligated to brackets with three different ligation methods. In each test, the brackets were moved a distance of 4 mm, 8 mm, and 12 mm across the central space, and the load cell readings were recorded on the digital display. The difference between the readings is noted. RESULTS: Stainless steel brackets with 0.016 NiTi archwire ligated with conventional, unconventional, and tooth-colored ligation with the movement of 4 mm, 8 mm, and 12 mm shows that the tooth-colored ligation indicating least frictional force decay. Comparison of frictional forces (in newtons) between ceramic brackets and stainless steel brackets using 0.016 NiTi wire for a movement of 12 mm shows that stainless steel bracket with tooth-colored ligation produced least frictional force compared with ceramic bracket. CONCLUSION: Based on this study results, we can conclude that stainless steel brackets produce less frictional force compared to ceramic brackets. Similarly, tooth-colored ligatures can be preferred to reduce friction during leveling stage.

2.
J Pharm Bioallied Sci ; 8(Suppl 1): S122-S125, 2016 Oct.
Article in English | MEDLINE | ID: mdl-27829762

ABSTRACT

OBJECTIVE: The purpose of this study is to elicit the amount of safety margin necessary around the ameloblastic lesion in view of preventing further recurrence. MATERIALS AND METHODS: The study consisted of 25 cases of mandibular ameloblastoma. Diagnosis was based on clinical and radiological analysis and confirmed by histopathological report. An incisional biopsy was done preoperatively to confirm the diagnosis. Segmental resection was planned for all the cases. After the resection, postoperative panoramic radiograph of the specimen was taken followed by histopathological examination of its margin to detect tumor cell infiltration. RESULTS AND CONCLUSION: In all our cases, the ameloblastoma was infiltrating in nature. A follow-up period of 10 years showed neither recurrence nor implant failure. In our study, we conclude our safe margin for infiltrating variant of ameloblastoma based on histopathological report of the resected specimen.

3.
J Assoc Physicians India ; 63(10): 32-4, 2015 10.
Article in English | MEDLINE | ID: mdl-27608689

ABSTRACT

OBJECTIVE: The objective of the study was to assess the prevalence of risk factors of diabetes among urban poor population in Chennai, Tamil Nadu, South India. STUDY AND METHODS: A cross-sectional study was conducted from Dec-2010 to Feb-2011 in Chennai city. Five hundred twenty-nine subjects aged above 18 years (409 women and 120 men) habitants of three slums were randomly selected. A structured questionnaire was used to collect the socio-demographic and clinical information. Anthropometric measures, blood pressure and random blood glucose (RCBG) estimation were done. Dietary intake was assessed using 24-hour diet recall and duration of physical activity/day in all components was recorded. RESULTS: The mean age and BMI of the study population was 45.4±12.8 years and 25.8±4.9 kg/m2 respectively. About 20.4% were illiterate and 34.8% were either unemployed, retired or housewives. Median family income per month was 3000 INR. Prevalence of obesity (≥25 kg/m2) was 57.3% and central obesity (≥90 cms in male and ≥80 cms in female) was 75.7%. The median duration spent in walking, standing and sitting were 30, 120, and 240 minutes/day respectively. There was a gross inadequacy in vegetable intake. The prevalence of self-reported diabetes and hypertension was 20.8% and 24.2%, respectively. Among the subjects without a previous diagnosis of diabetes, 12.5% had RCBG ≥140 mgs. 10.6% were diagnosed with hypertension. CONCLUSIONS: Sedentarism coupled with unhealthy diet pattern are the major contributing factors for the higher prevalence of diabetes and hypertension in urban poor population.


Subject(s)
Diabetes Mellitus/epidemiology , Poverty , Urban Population , Cross-Sectional Studies , Diet , Female , Humans , India/epidemiology , Male , Middle Aged , Prevalence , Risk Factors , Sedentary Behavior
4.
Indian Heart J ; 66(1): 5-10, 2014.
Article in English | MEDLINE | ID: mdl-24581089

ABSTRACT

AIMS: This study was planned to assess the development of cardiovascular disease (CVD) events over an 11-year period and to identify the associated risk factors that could predict the onset of CVD among subjects with type 2 diabetes. METHODS: Retrospective data of 249 patients (M:F 149:100) with type 2 diabetes, from a cohort of 7800 patients, attending a tertiary care center for diabetes from January 2000 to December 2011 were retrieved and analyzed for this study. Sociodemographic and habitual risk factors, baseline diabetes duration, HbA1c and time of onset of CVD and its risk factors were collected from case records. Person-years method was used to calculate incident rate of CVD. Binary logistic regression analyses were done to identify predictors associated with CVD and its risk factors. RESULTS: Incidence of CVD among subjects with diabetes was 5.6 cases/1000 person-years. Nearly 60% developed hypertension and dyslipidemia or both during the 11-year period. The most common complication was neuropathy (14.4%). Smoking [OR (95%CI)] [9.26 (1.6-54.9)] (p = 0.014) and heavy alcohol consumption [8.7 (1.1-69.8)] (p = 0.04) were significantly associated with CVD. Higher BMI was significantly associated with hypertension and dyslipidemia [2.4 (1.3-4.3)] (p = 0.003). CONCLUSIONS: Smoking and heavy alcohol consumption were significantly associated with CVD, and increased BMI was significantly associated with hypertension and dyslipidemia among subjects with type 2 diabetes in this study population. These findings emphasize the need for early identification and modification of risk factors associated with CVD events in patients with diabetes.


Subject(s)
Cardiovascular Diseases/diagnosis , Cardiovascular Diseases/epidemiology , Diabetes Mellitus, Type 2/diagnosis , Diabetes Mellitus, Type 2/epidemiology , Age Distribution , Aged , Alcoholism/epidemiology , Cardiovascular Diseases/therapy , Cohort Studies , Comorbidity , Diabetes Mellitus, Type 2/drug therapy , Female , Humans , Hypertension/epidemiology , Incidence , India/epidemiology , Logistic Models , Male , Middle Aged , Multivariate Analysis , Obesity/epidemiology , Retrospective Studies , Risk Assessment , Severity of Illness Index , Sex Distribution , Smoking/epidemiology
5.
J Diabetes Complications ; 28(2): 162-5, 2014.
Article in English | MEDLINE | ID: mdl-24461545

ABSTRACT

AIM: To assess the effect of diabetes on tuberculosis (TB) treatment outcome and sputum conversion among new smear-positive (NSP) cases registered under Directly Observed Treatment Short Course in South India. METHODS: Details on sputum conversion and TB treatment outcome were collected from case records of NSP cases (N = 332; M/F 247:85) registered at TB units of three districts in Tamil Nadu. Subjects were screened for diabetes and categorized as diabetic (TBDM) (n = 96; 73:23) and non-diabetic (TBnonDM) (n = 149; 109:40). RESULTS: Among 245 selected TB patients, 93.5% were cured, 1.6% completed TB treatment, 2% had TB treatment failure (TF), and 0.4% had treatment default (TD), 0.4% with MDR-TB and 2% death rate. At the end of intensive phase of TB treatment, 14.7% remained sputum positive in the TBDM group, whereas it was 3.5% in the TBnonDM group. Mean duration (days) for sputum conversion was higher in the TBDM group (64.2 ± 10.5) compared to the TBnonDM group (61.5 ± 7.5) (p<0.001). TF rate was higher (4.2% vs 0.7%) and MDR-TB (1%) was also seen in the TBDM group. No death and TD were seen among DM whereas it was 3.4 and 0.7% in TBnonDM. CONCLUSIONS: Delayed sputum conversion and high TB treatment failure rates were common in NSP cases with diabetes.


Subject(s)
Diabetes Complications/diagnosis , Diabetes Complications/therapy , Tuberculosis, Pulmonary/diagnosis , Tuberculosis, Pulmonary/therapy , Adult , Cytodiagnosis , Diabetes Complications/epidemiology , Female , Humans , India/epidemiology , Male , Middle Aged , Prognosis , Retrospective Studies , Sputum/microbiology , Treatment Outcome , Tuberculosis, Pulmonary/epidemiology , Tuberculosis, Pulmonary/pathology , Young Adult
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