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1.
J Shoulder Elbow Surg ; 32(7): 1370-1379, 2023 Jul.
Article in English | MEDLINE | ID: mdl-36907318

ABSTRACT

BACKGROUND: The Latarjet coracoid transfer procedure reliably stabilizes the glenohumeral joint for shoulder instability. However, complications such as graft osteolysis, nonunion and fracture continue to affect patient clinical outcomes. The double-screw (SS) construct is regarded as the gold standard method of fixation. SS constructs are associated with graft osteolysis. More recently, a double-button technique (BB) has been suggested to minimize graft-related complications. However, BB constructs are associated with fibrous nonunion. To mitigate this risk, a single screw combined with a single button (SB) construct has been proposed. It is thought that this technique incorporates the strength of the SS construct and allows micromotion superiorly to mitigate stress shielding-related graft osteolysis. AIMS: The primary aim of this study was to compare the failure load of SS, BB, and SB constructs under a standardized biomechanical loading protocol. The secondary aim was to characterize the displacement of each construct throughout testing. METHODS: Computed tomography scans of 20 matched-pair cadaveric scapulae were performed. Specimens were harvested and dissected free of soft tissue. SS and BB techniques were randomly assigned to specimens for matched-pair comparison with SB trials. A patient-specific instrument (PSI)-guided Latarjet procedure was performed on each scapula. Specimens were tested using a uniaxial mechanical testing device under cyclic loading (100 cycles, 1 Hz, 200 N/s) followed by a load-to-failure protocol (0.5 mm/s). Construct failure was defined by graft fracture, screw avulsion, and/or graft displacement of more than 5 mm. RESULTS: Forty scapulae from 20 fresh frozen cadavers with a mean age of 69.3 years underwent testing. On average, SS constructs failed at 537.8 N (SD 296.8), whereas BB constructs failed at 135.1 N (SD 71.4). SB constructs required a significantly greater load to fail compared with BB constructs (283.5 N, SD 162.8, P = .039). Additionally, SS (1.9 mm, IQR 0.87) had a significantly lower maximum total graft displacement during the cyclic loading protocol compared with SB (3.8 mm, IQR 2.4, P = .007) and BB (7.4 mm, IQR 3.1, P < .001) constructs. CONCLUSION: These findings support the potential of the SB fixation technique as a viable alternative to SS and BB constructs. Clinically, the SB technique could reduce the incidence of loading-related graft complications seen in the first 3 months of BB Latarjet cases. The study is limited to time-specific results and does not account for bone union or osteolysis.


Subject(s)
Joint Instability , Osteolysis , Shoulder Joint , Humans , Aged , Shoulder Joint/surgery , Joint Instability/surgery , Scapula/surgery , Bone Screws , Postoperative Complications
2.
J Arthroplasty ; 33(5): 1524-1529, 2018 05.
Article in English | MEDLINE | ID: mdl-29317156

ABSTRACT

BACKGROUND: The role of space suits in the prevention of orthopedic prosthetic joint infection remains unclear. Recent evidence suggests that space suits may in fact contribute to increased infection rates, with bioaerosol emissions from space suits identified as a potential cause. This study aimed to compare the particle and microbiological emission rates (PER and MER) of space suits and standard surgical clothing. METHODS: A comparison of emission rates between space suits and standard surgical clothing was performed in a simulated surgical environment during 5 separate experiments. Particle counts were analyzed with 2 separate particle counters capable of detecting particles between 0.1 and 20 µm. An Andersen impactor was used to sample bacteria, with culture counts performed at 24 and 48 hours. RESULTS: Four experiments consistently showed statistically significant increases in both PER and MER when space suits are used compared with standard surgical clothing. One experiment showed inconsistent results, with a trend toward increases in both PER and MER when space suits are used compared with standard surgical clothing. CONCLUSION: Space suits cause increased PER and MER compared with standard surgical clothing. This finding provides mechanistic evidence to support the increased prosthetic joint infection rates observed in clinical studies.


Subject(s)
Arthroplasty, Replacement/instrumentation , Cross Infection/microbiology , Intraoperative Complications/microbiology , Operating Rooms , Prosthesis-Related Infections/prevention & control , Protective Clothing , Surgical Wound Infection/microbiology , Air Movements , Air Pollutants/adverse effects , Arthroplasty, Replacement/adverse effects , Equipment Design , Humans , Infectious Disease Transmission, Professional-to-Patient/prevention & control , Orthopedics/methods , Particulate Matter/adverse effects , Space Suits
3.
Hip Int ; 24(2): 144-8, 2014.
Article in English | MEDLINE | ID: mdl-24186674

ABSTRACT

BACKGROUND: Metal ion release is common following total hip arthroplasty, yet postoperative levels have not been defined for most stems currently used in clinical practice. AIM: To assess metal ion release in the serum of patients with well functioning unilateral Exeter V40 primary total hip arthroplasties one year after surgery. METHODS: Whole blood chromium and serum cobalt levels were measured in 20 patients following primary total hip arthroplasty with the Exeter V40 stem and a variety of acetabular components one year after surgery. RESULTS: Whole blood chromium levels were within the normal range (10-100 nmol/L), with a single mild elevation of serum cobalt (normal <20 nmol/L). CONCLUSIONS: In well functioning primary unilateral total hip arthroplasty using the Exeter V40 stem with a variety of acetabular components one year post surgery, whole blood chromium levels are normal and serum cobalt elevations are rare and mild.


Subject(s)
Arthroplasty, Replacement, Hip , Metals/blood , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip/methods , Female , Hip Prosthesis , Humans , Ions/blood , Male , Middle Aged , Postoperative Period , Prosthesis Design
4.
J Orthop Surg (Hong Kong) ; 20(3): 336-40, 2012 Dec.
Article in English | MEDLINE | ID: mdl-23255641

ABSTRACT

PURPOSE: To evaluate the utility of blood cultures in the assessment of early postoperative fever in hip fracture patients with no other indicators of sepsis. METHODS: 101 blood cultures were drawn on postoperative days 0 to 5 to investigate 84 febrile episodes in 31 women and 30 men (mean age, 80 years) whose body temperature measured via the tympanic route was ≥ 38 ºC. Culture results of these 61 patients were divided into culture-positive and culture-negative groups for comparison. RESULTS: Of the 101 blood cultures, only 2 were positive: one was obtained 5 days after dynamic hip screw fixation, and the other 4 days after hemiarthroplasty. Both blood cultures grew coagulase-negative staphylococcal species, which were deemed to be skin contaminants not requiring change of patient management. 44 of these patients were treated with oral or intravenous antibiotics for a period of time. CONCLUSION: The risk of bacteraemia in patients with postoperative fever but no other symptoms of infection is low. Routine procurement of blood cultures in such patients is ineffective and of limited utility.


Subject(s)
Femoral Neck Fractures/surgery , Fever/etiology , Orthopedic Procedures/adverse effects , Aged , Aged, 80 and over , Bacteremia/etiology , Bacteremia/microbiology , Female , Fever/microbiology , Humans , Male , Microbiological Techniques , Retrospective Studies
5.
Orthopedics ; 35(4): e603-6, 2012 Apr.
Article in English | MEDLINE | ID: mdl-22495870

ABSTRACT

Antimicrobial resistance has been problematic since the advent of antibiotics. Patients with prosthetic joint infections often require prolonged courses of antibiotic therapy, with resistance commonly being the consequence. The rapid evolution of resistance poses a serious challenge in the treatment of infections and creates a need for new agents with novel mechanisms of bactericidal activity. Daptomycin, a cyclic lipopeptide naturally produced by Streptomyces roseosporus, is a newer agent approved for use in complicated skin, soft tissue, and prosthetic joint infections. To our knowledge, this article describes the first case of daptomycin-resistant heterogenous vancomycin intermediate-resistant Staphylococcus aureus (hVISA) in an 82-year-old man undergoing elective total knee arthroplasty in Queensland, Australia, with a subsequent deep prosthetic joint infection.A literature review is presented, and the increasing number of multi-resistant organisms and their implications for orthopedics are discussed. Worldwide reports of hVISA are reviewed. To our knowledge, this is the first article to describe daptomycin resistance in prosthetic joint infections. The role of newer antimicrobial agents, such as daptomycin, and strategies to minimize antibiotic resistance are examined.


Subject(s)
Daptomycin/therapeutic use , Gram-Positive Bacterial Infections/etiology , Gram-Positive Bacterial Infections/therapy , Knee Prosthesis/adverse effects , Prosthesis-Related Infections/therapy , Anti-Bacterial Agents/therapeutic use , Drug Resistance, Bacterial , Humans , Male , Treatment Outcome
6.
J Arthroplasty ; 27(3): 375-7, 2012 Mar.
Article in English | MEDLINE | ID: mdl-21802251

ABSTRACT

Postoperative fever in arthroplasty patients is common. The value of diagnostic workup of fever in this instance is of questionable utility. Studies have shown that blood cultures in this scenario add little to clinical management, but sample sizes have been small and the use of blood cultures in this setting continues. This study aimed to examine the value of blood cultures in the assessment of postoperative fever in a large arthroplasty population. The medical records of 101 patients who had 141 blood culture sets taken during a 2-year period were retrospectively analyzed. Of the 141 blood culture sets, only 2 returned positive results. These were both thought to be as a result of skin contamination at the time of venipuncture. No infectious sequelae occurred in either patient. We conclude that blood cultures have no role to play in the assessment of the febrile, otherwise asymptomatic arthroplasty patient in the early postoperative period.


Subject(s)
Arthroplasty, Replacement , Fever/blood , Fever/microbiology , Infections/blood , Infections/microbiology , Postoperative Complications/blood , Postoperative Complications/microbiology , Humans , Retrospective Studies
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