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1.
Rev. esp. anestesiol. reanim ; 61(7): 385-387, ago.-sept. 2014.
Article in English | IBECS | ID: ibc-124930

ABSTRACT

We report the anesthetic management with total intravenous anesthesia of a 61-year-old male diagnosed with limb-girdle muscular dystrophy admitted for replacement of ascending aorta due to an aortic aneurysm. Limb-girdle muscular dystrophy belongs to a genetically heterogeneous group of muscular dystrophies involving shoulder and hip girdles. Although the risk of malignant hyperthermia does not seem to be increased in these patients compared with the general population, the exposure to inhaled anesthetics and succinylcholine should probably be avoided because these patients have a predisposition to hyperkalemia and rhabdomyolysis. We chose to use total intravenous anesthesia with propofol, remifentanil and muscle relaxants to reduce oxygen consumption, and later to reduce the doses of propofol and remifentanil. The combination of a carefully planned anesthetic strategy, anesthetic depth, and neuromuscular blockade monitoring is explained (AU)


Presentamos el tratamiento anestésico con anestesia total intravenosa de un varón de 61 años diagnosticado de distrofia muscular de cinturas para sustitución de aorta ascendente por aneurisma aórtico. La distrofia muscular de cinturas es un grupo genéticamente heterogéneo de distrofias musculares que afecta predominantemente la cintura escapular y pélvica. Aunque el riesgo de hipertermia maligna no parece estar aumentado en estos pacientes en comparación con la población general, la exposición a anestésicos inhalatorios y succinilcolina probablemente deba evitarse ya que existe una predisposición a la hiperpotasemia y rabdomiólisis. Utilizamos anestesia intravenosa total con propofol y remifentanilo, además de bloqueanttes musculares durante el procedimiento quirúrgico, para reducir el consumo de oxígeno y minimizar las dosis de propofol y remifentanilo. La combinación de una estrategia anestésica cuidadosa, monitorización de bloqueo neuromuscular y profundidad anestésica se describen a continuación (AU)


Subject(s)
Humans , Male , Middle Aged , Aortic Aneurysm/drug therapy , Aortic Aneurysm/surgery , Muscular Dystrophies/complications , Muscular Dystrophies/drug therapy , Anesthesia, Intravenous/methods , Anesthesia, Intravenous , Anesthesia, Intravenous/instrumentation , Anesthesia, Intravenous/standards , Anesthesia, Intravenous/trends , Fentanyl/therapeutic use , Acetaminophen/therapeutic use
2.
Rev. esp. anestesiol. reanim ; 61(3): 154-156, mar. 2014.
Article in Spanish | IBECS | ID: ibc-119967

ABSTRACT

Presentamos el caso de un paciente de 77 años programado para cirugía de revascularización coronaria. Coincidiendo con la infusión de levosimendán como precondicionamiento previo a la cirugía, se produjo la rotura de un aneurisma ilíaco derecho, lo que obligó a suspender la intervención y realizar un bypass aortobifemoral urgente. Creemos que esta rotura pudo verse precipitada por el incremento de la presión transmural debida al efecto inotrópico del levosimendán sobre un vaso dilatado y aterosclerótico. Por lo que sabemos, no existe ningún caso de rotura de aneurisma como complicación durante la infusión de levosimendán, pero la coincidencia de acontecimientos en el tiempo nos hace pensar en cierta relación causa-efecto (AU)


We present the case of a 77-year-old patient scheduled for coronary artery bypass. During the infusion of levosimendan as preconditioning for surgery, the break of an aneurysm took place iliac rightly, which forced to suspend the intervention and to fulfil an urgent bypass aortobyfemoral. We believe that this break could turn precipitated by the increase of the pressure transmural owed to the effect inotropic of the levosimendan on an extensive glass and aterosclerotic. For what we know, there does not exist any case of break of aneurysm as complication during the infusion of levosimendan, but the coincidence of events in the time makes us think about certain cause and effect relationship (AU)


Subject(s)
Humans , Male , Aged , Iliac Aneurysm/complications , Aneurysm, Ruptured/complications , Anesthetics/adverse effects , Acute Coronary Syndrome/surgery , Preoperative Care/methods , Myocardial Revascularization
3.
Rev Esp Anestesiol Reanim ; 61(3): 154-6, 2014 Mar.
Article in Spanish | MEDLINE | ID: mdl-23664061

ABSTRACT

We present the case of a 77 year-old patient scheduled for coronary artery bypass. During the infusion of levosimendan as preconditioning for surgery, a rupture of right common iliac artery occurred. Surgery was delayed and an urgent aorto-bifemoral bypass was performed. We believe that the rupture of the artery was triggered by an increase in transmural pressure due to the inotropic effects of levosimendan in a dilated diseased vessel. To our knowledge, there are no cases of aneurysm rupture as a complication during levosimendan infusion, but the coincidence of events in time strongly suggests some kind of causal relationship.


Subject(s)
Aneurysm, Ruptured/etiology , Cardiotonic Agents/adverse effects , Coronary Artery Bypass , Hydrazones/adverse effects , Iliac Aneurysm/complications , Ischemic Preconditioning/adverse effects , Pyridazines/adverse effects , Vasodilator Agents/adverse effects , Aged , Atherosclerosis/complications , Atherosclerosis/physiopathology , Cardiotonic Agents/therapeutic use , Causality , Hemodynamics , Humans , Hydrazones/therapeutic use , Iliac Aneurysm/physiopathology , Infusions, Intravenous , Male , Pressure , Pyridazines/therapeutic use , Simendan , Vasodilation/drug effects , Vasodilator Agents/therapeutic use
4.
Rev Esp Anestesiol Reanim ; 61(7): 385-7, 2014.
Article in English | MEDLINE | ID: mdl-24035539

ABSTRACT

We report the anesthetic management with total intravenous anesthesia of a 61-year-old male diagnosed with limb-girdle muscular dystrophy admitted for replacement of ascending aorta due to an aortic aneurysm. Limb-girdle muscular dystrophy belongs to a genetically heterogeneous group of muscular dystrophies involving shoulder and hip girdles. Although the risk of malignant hyperthermia does not seem to be increased in these patients compared with the general population, the exposure to inhaled anesthetics and succinylcholine should probably be avoided because these patients have a predisposition to hyperkalemia and rhabdomyolysis. We chose to use total intravenous anesthesia with propofol, remifentanil and muscle relaxants to reduce oxygen consumption, and later to reduce the doses of propofol and remifentanil. The combination of a carefully planned anesthetic strategy, anesthetic depth, and neuromuscular blockade monitoring is explained.


Subject(s)
Anesthesia, Intravenous , Aortic Aneurysm/surgery , Blood Vessel Prosthesis Implantation , Muscular Dystrophies, Limb-Girdle/complications , Androstanols/administration & dosage , Anesthesia, Inhalation , Anesthetics, Intravenous/administration & dosage , Aortic Aneurysm/complications , Contraindications , Disease Susceptibility , Humans , Hyperkalemia/prevention & control , Intraoperative Complications/prevention & control , Male , Middle Aged , Neuromuscular Monitoring , Neuromuscular Nondepolarizing Agents/administration & dosage , Oxygen Consumption , Piperidines/administration & dosage , Propofol/administration & dosage , Remifentanil , Respiratory Muscles/physiopathology , Rhabdomyolysis/prevention & control , Rocuronium , Sugammadex , gamma-Cyclodextrins/administration & dosage
5.
Rev. esp. cir. ortop. traumatol. (Ed. impr.) ; 53(5): 300-304, sept.-oct. 2009. tab, graf
Article in Spanish | IBECS | ID: ibc-62155

ABSTRACT

Objetivos: Valorar la eficacia del bloqueo del femoral (punción única guiada por neuroestimulación) como técnica analgésica en el postoperatorio de artroplastia total de rodilla (ATR) y comparar si hay diferencias si se utilizan como anestésico local bupivacaína 0,25% sola (30ml) o mezcla de bupivacaína 0,25% (15ml) con mepivacaína 2% (15ml), en cuanto al inicio de acción o duración del efecto analgésico. Material y método: Estudio prospectivo, observacional, aleatorizado, de un grupo de 40 pacientes, intervenidos de ATR, mediante la utilización del bloqueo del femoral como técnica analgésica en postoperatorio. Resultados: Se han encontrado diferencias estadísticamente significativas en tiempo de inicio de analgesia usando mezcla de anestésicos (X¯: 2,90min; desviación típica [DT]: 1,36) frente al uso de bupivacaína sola (X¯: 3,85min; DT: 1,21) (p = 0,027). Se obtuvo una mayor duración analgésica con la bupivacaína (X¯: 22h; DT: 10,47) frente a la utilización de la mezcla (X¯: 15,2h; DT: 9,2) (p=0,036). Conclusiones: Para la realización del bloqueo, la adición de mepivacaína a la bupivacaína no aporta ningún beneficio clínico en cuanto a acortamiento en la latencia de inicio de acción, y puede ser contraproducente el uso de la mezcla por la pérdida en horas de analgesia. El bloqueo femoral es una técnica segura, con escasas complicaciones y muy bien aceptada por los pacientes (AU)


Purpose: To assess the efficacy of femoral nerve block (single neurostimulation-guided puncture) as an analgesic technique in postoperative total knee replacement (TKR) in an attempt to identify any potential differences between the use of bupivacaine 0.25% (30ml) or a bupivacaine 0.25% (15ml) + mepivacaine 2% (15ml) mixture as local anesthetics, as regards the inception of their activity and/or the duration of their analgesic effect. Material and methods: Prospective randomized observational study of a group of 40 patients subjected to TKR, with femoral nerve block being used as postoperative analgesic technique. Results: Statistically significant differences were found in terms of the onset of analgesic effect using an anesthetics-mixture (X¯: 2.90min; SD: 1`36) as compared with bupivacaine on its own (X¯: 3.85min; SD: 1.21); (p=0.027). The analgesic effect lasted longer with bupivacaine (X¯: 22h; SD: 10.47) as compared with the mixture (X¯: 15.2h; SD: 9.2) (p=0,036). Conclusions: Addition of mepivacaine to bupivacaine does not contribute any clinical benefit to the nerve block as far as reducing the latency of onset. The use of the mixture could even be counterproductive given the shortening in the effect of analgesia. Femoral block is a safe technique with few complications, which is well accepted by patients (AU)


Subject(s)
Humans , Male , Female , Arthroplasty, Replacement, Knee/methods , Femoral Nerve/surgery , Bupivacaine/therapeutic use , Mepivacaine/therapeutic use , Analgesia/trends , Analgesia , Prospective Studies , Signs and Symptoms
10.
Pharm. care Esp ; 10(1): 14-21, ene.-mar. 2008. tab
Article in Spanish | IBECS | ID: ibc-147755

ABSTRACT

La cardiopatía isquémica es una enfermedad crónica en la que se debe mantener la prevención secundaria de forma indefinida. Para un subgrupo de pacientes con cardiopatía isquémica, la revascularización coronaria constituye una opción terapéutica en la que se ha demostrado que una prevención secundaria farmacológica adecuada disminuye la morbilidad y la mortalidad a largo plazo. El objetivo de este estudio es analizar el cumplimiento de las guías clínicas de prevención secundaria farmacológica en una muestra de pacientes operados de revascularización coronaria. Se realizó un estudio prospectivo observacional sobre un grupo de 35 pacientes varones intervenidos de revascularización coronaria en el Hospital Meixoeiro (Vigo), analizando las prescripciones farmacológicas al ingreso para cirugía, al alta y tras un seguimiento medio de 2 años. Se comprobó un adecuado cumplimiento de la prevención secundaria farmacológica con antiagregantes y betabloqueadores, acompañado, sin embargo, de un descenso en la prescripción de inhibidores de la enzima conversora de la angiotensina (IECA) tras la cirugía. El dato más relevante fue una disminución no justificada en la prescripción de hipolipemiantes al alta del paciente, que se corrigió durante el seguimiento. Nuestros resultados apoyan la implantación de un programa específico de atención farmacéutica para estos pacientes (AU)


Secondary prevention recommendations must be maintained indefinitely in patients with coronary artery disease. Pharmacological secondary prevention demonstrated a long-term benefit in morbidity and mortality after coronary artery bypass grafting surgery. In this paper we analyze the observance of clinical guidelines of pharmacological secondary prevention in patients submitted to coronary surgery. We performed a prospective observational study on 35 male patients submitted to elective coronary artery bypass grafting in Hospital Meixoeiro (Vigo). We recorded prescriptions on admission before surgery, on hospital discharge, and after a two years follow-up. There was a correct observance of pharmacological secondary prevention guidelines regarding antiplatelet drugs and beta-blockers, but with a decrease in prescription of angiotensinconverting enzyme inhibitors after surgery. The most important finding was an unjustified decrease in prescription of lipid-lowering agents on discharge, which was corrected on follow-up. Our results support the implementation of a pharmaceutical care program for these patients (AU)


Subject(s)
Humans , Myocardial Revascularization/rehabilitation , Myocardial Ischemia/drug therapy , Adrenergic beta-Antagonists/therapeutic use , Platelet Aggregation Inhibitors/therapeutic use , Secondary Prevention/methods , Prospective Studies , Angiotensin Receptor Antagonists/therapeutic use , Hypolipidemic Agents/therapeutic use , Treatment Outcome
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